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  • 1995-1999  (4)
  • Therapie  (2)
  • Axilladissektion  (1)
  • Brainstem  (1)
  • 1
    ISSN: 1432-0568
    Keywords: Brainstem ; Mechanosensory system ; Otavolateral efferents ; Teleost ; Tract-tracing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The efferent neurons of the lateral line system of the euteleost Aplocheilus lineatus and the osteoglossomorph Pantodon buchholzi, both surface feeding fish, were examined by neuronal tract tracing. Besides horseradish peroxidase, fluorescent dextrans were used as tracers to allow simultaneus visualization of projections from different lateral line branches. Labeled efferent neurons were found in nuclei situated in the medulla ventral of ventricle IV. This position resembles the octavolateralis efferent nucleus of previous studies. The number of labeled cells in the efferent nucleus is low in both species. Most neurons were found ipsilaterally to the application site, some along the midline and only very few contralaterally. The size of efferent cells differs distinctly between Aplocheilus, possessing small cellbodies (length 16.5 μm), and Pantodon, which has very large efferent cells (length 47.0 μm). Efferent axon bundles course rostrally in both species, leaving the brain at the level of the anterior lateral line nerve. Only Aplocheilus has in addition lateral axon bundles leaving the brain at the level of the posterior lateral line nerve. After application of one fluorescent tracer to the lateral ramus and a different fluorescent tracer to the superficial ophtalmic ramus in a given animal, double-labeling of efferent cells hardly ever occurs. If the neuromasts I and IV of the dorsal skull of Pantodon are applied with one fluorescent tracer each, ∼10% of centrally labeled cells are double-labeled. Considering the results of double-labeling, the concept of a differential innervation of lateral line branches is supported and discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Chirurg 68 (1997), S. 1258-1261 
    ISSN: 1433-0385
    Keywords: Key words: Staging breast cancer ; Sentinel lymph node ; Axillary lymph-node dissection ; Gamma probe. ; Schlüsselwörter: Brustkrebsstaging ; Sentinel-Lymphknoten ; Axilladissektion ; Szintillationsmeßsonde.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Ziel unserer Untersuchungen ist es, die Wertigkeit und Anwendbarkeit der Sentinel-Lymphadenektomie (SLNE) im Hinblick auf das Staging der regionären Lymphknoten beim Mammacarcinom zu evaluieren. Wie für das maligne Melanom dokumentiert, stellt der 1. Lymphknoten [Sentinel-Lymphknoten (SLN)] im Lymphabflußgebiet des Primärtumors auch gleichzeitig die zu erwartende 1. Lokalisation einer möglichen Lymphknotenmetastasierung dar. Die dargestellten Ergebnisse beziehen sich auf 12 Patientinnen, wovon die beschriebene Methodik in 11 Fällen anwendbar war. Nur einmal korrelierte das histologische Ergebnis des SLN und des Axilladissektats nicht miteinander; 3 mal war der SLN carcinompositiv. Nach Vorliegen ausreichend großer Patientenzahlen und einer entsprechend langen Nachbeobachtungszeit bietet sich in Zukunft durch die SLNE evtl. die Möglichkeit, die Anzahl der zu Stagingzwecken durchgeführten axillären Lymphknotendissektionen beim Mammacarcinom deutlich zu reduzieren.
    Notes: Summary. The objective of our trial was to evaluate the significance and usefulness of sentinel lymphadenectomy (SLNE) for the staging of regional lymph nodes in breast cancer patients. The study presented illustrates the method and our results. As has been documentated for melanoma, the first lymph node [sentinel node (SLN)] to receive lymphatic drainage from a primary tumor is the expected first site of lymph-node metastasis. The database presented includes 12 patients with operable breast cancer and clinically negative lymph nodes. In 11 cases the described method was applicable. In only one case was there no correlation between the histology of the SLN and the axillary specimen. Three SLN were tumor-positive. Successful completion of examination of a large number of patients with a long follow-up has the potential of reducing the number of axillary dissections and of significantly reducing morbidity in the majority of breast cancer patients.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 382 (1997), S. 226-230 
    ISSN: 1435-2451
    Keywords: Angiosarcoma ; Spleen ; Diagnosis ; Pathology ; Immunohistochemistry ; Surgery ; Angiosarkom ; Milz ; Diagnostik ; Pathologie ; Immunhistochemie ; Therapie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit ca. 140 publizierten Fällen stellt das Angiosarkom der Milz eine sehr seltene Erkrankung dar, die durch ihre hochmaligne Verlaufsform charakterisiert ist. Wir berichten über den Fall eines 42jährigen Patienten, dessen Befunde zunächst an eine disseminierte Echinokokkose denken ließen. Die richtige Diagnose konnte letztlich erst histologisch und immunhistochemisch nach Splenektomie gestellt werden. Der Patient verstarb 3 Monate nach Diagnosestellung bei ausgedehnter Lebermetastasierung. Anhand einer Literaturübersicht werden diagnostische und therapeutische Möglichkeiten diskutiert.
    Notes: Abstract Angiosarcoma of the spleen is a very rare but highly malignant vascular neoplasm. So far only 140 cases have been reported. A 42-year-old patient is presented in which the radiologic imaging misled to the diagnosis of infiltrating echinococcosis. After splenectomy histological and immunohistochemical staining gave proof of metastatic angiosarcoma. The patient died three months later as a consequence of multiple organ dysfunction syndrome. The literature is reviewed in regard to clinical features, diagnosis and therapy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 382 (1997), S. 226-230 
    ISSN: 1435-2451
    Keywords: Key words Angiosarcoma ; Spleen ; Diagnosis ; Pathology ; Immunohistochemistry ; Surgery ; Schlüsselwörter Angiosarkom ; Milz ; Diagnostik ; Pathologie ; Immunhistochemie ; Therapie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit ca. 140 publizierten Fällen stellt das Angiosarkom der Milz eine sehr seltene Erkrankung dar, die durch ihre hochmaligne Verlaufsform charakterisiert ist. Wir berichten über den Fall eines 42jährigen Patienten, dessen Befunde zunächst an eine disseminierte Echinokokkose denken ließen. Die richtige Diagnose konnte letztlich erst histologisch und immunhistochemisch nach Splenektomie gestellt werden. Der Patient verstarb 3 Monate nach Diagnosestellung bei ausgedehnter Lebermetastasierung. Anhand einer Literaturübersicht werden diagnostische und therapeutische Möglichkeiten diskutiert.
    Notes: Abstract Angiosarcoma of the spleen is a very rare but highly malignant vascular neoplasm. So far only 140 cases have been reported. A 42-year-old patient is presented in which the radiologic imaging misled to the diagnosis of infiltrating echinococcosis. After splenectomy histological and immunohistochemical staining gave proof of metastatic angiosarcoma. The patient died three months later as a consequence of multiple organ dysfunction syndrome. The literature is reviewed in regard to clinical features, diagnosis and therapy.
    Type of Medium: Electronic Resource
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