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  • 1995-1999  (3)
  • Brain banking  (1)
  • Column liquid chromatography  (1)
  • D17S5  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 109 (1996), S. 98-99 
    ISSN: 1437-1596
    Keywords: Population genetics ; PCR-FLP ; D17S5 ; Spanish population ; YNZ22
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract The fragment length polymorphism YNZ22 (D17S5) was analysed for a sample of 207 unrelated individuals living in Madrid (Spanish Caucasians) using PCR-methodology and high resolution separation. Hardy-Weinberg expectations (HWE) were calculated after pooling alleles into four groups. No deviations from HWE were detectable using the conventional χ2-test. The power of discrimination was estimated as 0.96 and the mean paternity exclusion chance as 0.7587. A comparison of the allele frequency distribution with those of other Caucasian groups revealed no major differences.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1435-1463
    Keywords: Brain banking ; post mortem research ; schizophrenia ; affective disorders ; European consensus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way. In this publication we present the consensus of the European work group 〉European Dementia and Schizophrenia Network〈, granted by the BIOMED I project of the EU, on minimal neuropathological and clinical requirements to include brains of patients with schizophrenia and affective disorders in post mortem studies. The description of clinical prerequisites in different EU countries and institutions is followed by a consensus on tissue handling, a consensus on minimal neuropathological criteria and a consensus on minimal clinical diagnostic criteria including clinical vignette, family, social, educational/professional and general medical histories, general physical history including neurostatus, neurological, psychiatric, medication and general pathological histories, psychostatus, laboratory tests and a history provided by family/health care giver questionaire. This publication should give help to interconnect different European brain bank centers on a basis of standarized protocols.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Tryptophan ; Chiral separations ; Diode-laser polarimetric detection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The combined utilization of photometric, fluorimetric and polarimetric detection liquid chromatography detectors in series for the identification and quantification of D-tryptophan and L-tryptophan was evaluated. Detection limits of about 1 μg were established with the range of linearity extending to about 100 μg. The relative standard deviation of the D-form and L-form tryptophan were 7.32 and 4.22%, respectively. The amount unknown of tryptophan enantiomers in the different mixtures was determined with an accuracy of 1.58% at the 40 μg injection level.
    Type of Medium: Electronic Resource
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