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  • 11
    Electronic Resource
    Electronic Resource
    Abnormality in the Urostyle of the Common Frog (1887)
    [s.l.] : Nature Publishing Group
    Nature 35 (1887), S. 344-344 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ATTENTION has recently been drawn to abnormalities in the vertebral column of Rana. (See Baurne, Quarterly Journal of Microscopical Science, January 1884; Howes, Anatomischer Anzeiger, 1 Jahrgang, 1886, Nr. 11; Lloyd Morgan, NATURE, November 1886.) One form of such abnormality is the addition ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/035344a0
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  • 12
    Electronic Resource
    Electronic Resource
    Abnormalities in the Vertebral Column of the Common Frog (1886)
    [s.l.] : Nature Publishing Group
    Nature 35 (1886), S. 53-53 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN preparing skeletons of the frog, my students came aeross the following abnormalities in the vertebral column, a record of which may be not without interest:— (1) In a large Rana temporaria, the centrum of the eighth vertebra, instead of being biconcave (amphiccelous), is concavo-convex ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/035053c0
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  • 13
    Electronic Resource
    Electronic Resource
    Some Experiments on the Viscosity of Ice (1885)
    [s.l.] : Nature Publishing Group
    Nature 32 (1885), S. 16-17 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THAT ice will change its form under the influence of pressure o*o is exemplified at large in glaciers, and may be illustrated by experiments in the laboratory. How far this is due to a true viscosity, and how far to a rearrangement of the particles by melting and regelation, is a question the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/032016a0
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  • 14
    Electronic Resource
    Electronic Resource
    Suicide of Scorpions (1883)
    [s.l.] : Nature Publishing Group
    Nature 27 (1883), S. 313-314 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SPEAEKING of scorpion suicide, Mr. G. J. Romanes in his “Animal Intelligence writes: “Still I think that so remarkable a fact unquestionably demands further corroboration before we shall be justified in accepting it unreservedly” (p. 225). Some years ago I made some experiments and observations ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/027313b0
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  • 15
    Electronic Resource
    Electronic Resource
    Scorpion Suicide (1883)
    [s.l.] : Nature Publishing Group
    Nature 27 (1883), S. 530-530 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] I AM sorry that my experiments on scorpion suicide has given pain to some of your correspondents. Allow me to explain in a few words the object of my investigation. It is commonly believed in this colony and elsewhere that scorpions commit suicide; Dr. Allen Thomson, in a letter to NATURE, lent ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/027530a0
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  • 16
    Electronic Resource
    Electronic Resource
    Instinct (1884)
    [s.l.] : Nature Publishing Group
    Nature 29 (1884), S. 405-405 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WERE it merely for the sake of reiterating my views, I should not feel justified in commenting upon Mr. Romanes' letter on instinct in last week's NATURE (p. 379). He seems, however, to have understood my “subjective verification” in a sense somewhat different to that which I intended to convey ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/029405a0
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  • 17
    Electronic Resource
    Electronic Resource
    The use of radionuclide techniques in the assessment of alveolar-capillary membrane permeability on the intensive care unit (1990)
    Springer
    Intensive care medicine 16 (1990), S. 363-371 
    Details
    ISSN: 1432-1238
    Keywords: Intensive care ; Radionuclides ; Lung injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion Three isotopic methods of estimating alveolar-capillary membrane permeability have been described. The first, radiolabelled HSA, is crude, and appears to have no clinical applications. Pulmonary99mTc-DTPA clearance studies are relatively easy to perform, but suffer from their high sensitivity and variations in technique from centre to centre. The double isotopic measurement of PAI has only been adopted by a few centres, but may offer reliable assessment of the pulmonary endothelial permeability which is probably an early marker of acute lung injury. None of these techniques has proved predictive of outcome in ARDS. However, trials where alveolar-capillary membrane permeability is assessed before clinical evidence of lung injury is apparent have yet to be conducted. Thus at present, methods of assessing alveolar-capillary membrane permeability, particularly capillary endothelial integrity, may prove to be more useful in monitoring new therapeutic interventions in lung injury, rather predicting outcome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01735173
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  • 18
    Electronic Resource
    Electronic Resource
    Blood lactate and mixed venous-arterial PCO2 gradient as indices of poor peripheral perfusion following cardiopulmonary bypass surgry (1991)
    Springer
    Intensive care medicine 17 (1991), S. 320-324 
    Details
    ISSN: 1432-1238
    Keywords: Blood lactate ; Acid base balance ; Cardiopulmonary bypass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Conventional indices of tissue perfusion after surgery involving cardiopulmonary bypass (CPB) may not accurately reflect disordered cell metabolism. Venous hypercarbia leading to an increased veno-arterial difference in CO2 tensions (V-aCO2 gradient) has been shown to reflect critical reductions in systemic and pulmonary blood flow that occur during cardiorespiratory arrest and septic shock. We therefore measured plasma lactate levels and V-aCO2 gradients in 10 patients (mean age 57.2 years) following CPB and compared them with conventional indices of tissue perfusion. Plasma lactate levels, cardiac index (CI) and oxygen uptake $$(\dot VO_2 )$$ all increased significantly (p〈0.05 vs baseline levels) up to 3h following surgery. Oxygen delivery $$(\dot DO_2 )$$ did not change. Plasma lactate levels correlated significantly with CI (r=0.47,p〈0.01). V-aCO2 fell significantly with time (p〈0.01 vs baseline). There was an inverse relationship between V-aCO2 and cardiac index and V-aCO2 and lactate (r=−0.37,p〈0.05;r=−0.3,p〈0.05 respectively). We conclude that blood lactate, CI and $$\dot VO_2 $$ increase progressively following CPB. An increase in lactate was associated with a decrease in V-aCO2. An increase in V-aCO2 was not therefore associated with evidence of inadequate tissue perfusion as indicated by an increased blood lactate concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01716189
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  • 19
    Electronic Resource
    Electronic Resource
    Organization of corneal afferent axons in the trigeminal nerve root entry zone in the cat (1987)
    Springer
    Experimental brain research 68 (1987), S. 411-416 
    Details
    ISSN: 1432-1106
    Keywords: Trigeminal organization ; Cornea ; HRP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out in cats to learn the location of sensory axons from the cornea in the trigeminal nerve root just prior to its entry into the brainstem. HRP injected into the cornea labelled these axons and indicated they were not restricted to the ophthalmic division of the nerve root as had been indicated from previous studies. These findings, if representative of other branches of this nerve, offer a partial explanation for the variable preservation of function following transection of an entire division of the trigeminal nerve root in cases of trigeminal neuralgia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00248806
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  • 20
    Electronic Resource
    Electronic Resource
    Continuous veno-venous haemofiltration following cardio-pulmonary bypass (1993)
    Springer
    Intensive care medicine 19 (1993), S. 290-293 
    Details
    ISSN: 1432-1238
    Keywords: Acute renal failure ; Cardio-pulmonary bypass ; Haemofiltration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To study the impact of continuous veno-venous haemofiltration on survival in patients with acute renal failure (ARF) following cardio-pulmonary bypass (CPB) surgery. Design A retrospective study of all patients requiring haemofiltration after CPB over a 2 year period. Setting A 20 bedded, adult cardothoracic intensive care unit in a postgraduate teaching hospital. Patients 35 patients (26 male, age range 24–74 years) required haemofiltration (2.7% of the total number of patients undergoing CPB). Main results Cardiovascular failure post CPB was the commonest causes of ARF (n=16). Indications for haemofiltration were ureamia (21), oligo-anuria (11), volume overload (2) and hyperkalaemia (1). Mean time from CPB to the initiation of haemofiltration was 8 days (range 0–15 days). Mean urea was 30 mmol/l and creatinine 362 μmol/l immediately prior to treatment. Urea was well-controlled in all patients, although 2 needed haemodiafiltration. Twenty-six patients died during their admission to the ICU (74% mortality). A further 3 patients died during their hospital admission, following discharge from ICU. Outcome was particularly poor in patients with cardiovascular failure following CPB (16 cases, 0 survivors). Survivors tended to commence filtration earlier (mean of 4 vs 7 days for non-survivors) and required treatment for a mean period of 8 days (range 1–26 days). Survival was determined by the number of failed organ systems at the start of haemofiltration. Thus, 100% of patients with single system failure survived, compared to only 10% with 3 or more system failure. Conclusions Despite the theoretical advantages of haemofiltration and the effective control of uraemia the mortality associated with ARF following CPB remains high and is probably determined by the number of failed organs systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01690550
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