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  • 1990-1994  (1)
  • 1985-1989  (3)
  • Liver injury  (2)
  • ABRM  (1)
  • Aromatic retinoid  (1)
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Material
Years
  • 1990-1994  (1)
  • 1985-1989  (3)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Impaired acetaldehyde metabolism in partially hepatectomized rats (1985)
    Springer
    Research in experimental medicine 185 (1985), S. 13-20 
    Details
    ISSN: 1433-8580
    Keywords: Acetaldehyde ; Ethanol ; Partial hepatectomy ; Liver injury ; Carbon tetrachloride
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two-thirds hepatectomy in rats resulted in elevated blood ethanol and acetaldehyde levels as compared to those of sham operated and CCl4-induced toxic injured rats. The acetaldehyde/ethanol ratio increased also. Although the liver mass regenerated within 3 days, ethanol metabolism remained disturbed. Mitochondrial aldehyde dehydrogenase activity was significantly diminished only following partial hepatectomy. The results suggest that abnormal ethanol and especially acetaldehyde metabolism in partially hepatectomized rats is not due simply to reduced liver tissue but to a diminished aldehyde dehydrogenase activity in the remaining tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851523
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of high hepatic acetaldehyde level following simultaneous administration of ethanol and cyanamide on liver function in rats (1985)
    Springer
    Research in experimental medicine 185 (1985), S. 221-225 
    Details
    ISSN: 1433-8580
    Keywords: Ethanol ; Acetaldehyde ; Liver injury ; Cyanamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Extremely high concentrations of hepatic acetaldehyde were induced in rats by the intragastric administration of ethanol and cyanamide, an aldehyde dehydrogenase inhibitor; and these high levels were maintained for 4 weeks. Liver function tests, including mitochondrial ornithine carbamoyltransferase (OCT) and GOT activities, were within normal limits, and no increase in either hepatic triglyceride or collagen contents was observed. These results suggest that hepatotoxic effects of ethanol are not derived from the high acetaldehyde levels in the liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01852036
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effect of orally administered aromatic retinoid on murine Langerhans cells (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 198-203 
    Details
    ISSN: 1432-069X
    Keywords: Aromatic retinoid ; Langerhans cells ; Ia antigens ; Ia-reactive cloned T cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of orally administered aromatic retinoid (Ro 10-9359) on murine epidermal Langerhans cells (LC) was studied in vivo and in vitro. Daily administration of retinoid caused a transient increase in LC density, as determined by staining for Ia antigens, during the first few days of treatment and thereafter a continuing decrease that reached a maximum at 2 weeks. In addition, the morphology and location in the epidermis had been altered. When the treatment was continued to 4 weeks, the density of LC returned to normal. The Ia-antigen-presenting function of epidermal cells to an allo-Ia-reactive cloned T cell line was elevated at all stages of retinoid treatment examined. This elevation did not correlate with the density of histochemically stainable Ia+ LC. These findings suggest that orally administered retinoid profoundly alters the functional capacity of Ia+ LC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00413258
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Comparative aspects of structure and action of molluscan neuropeptides (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 448-456 
    Details
    ISSN: 1420-9071
    Keywords: Neuropeptide ; Mollusca ; ABRM ; Mytilus ; Achatina ; Helix ; d-amino acid residue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A number of neuropeptides were isolated from the ganglia and muscles of molluscs, and their actions were examined. Diverse neuropeptides, in addition to several classical neurotransmitters, were suggested to be involved in the regulation of the anterior byssus retractor muscle ofMytilus. A wide structural variety of members of theMytilus inhibitory peptide family was observed in each of the generaMytilus, Achatina andHelix. Gly-Trp-NH2, the C-terminal dipeptide fragment of the neuropeptide AGPWamide, showed a more potent action than the parent peptide in all of the muscles examined. Peptides related to some molluscan neuropeptides were found to be distributed interphyletically. Some neuropeptides containing ad-amino acid residue were found inAchatina andMytilus. These aspects of molluscan neuropeptides are thought not to be exceptional.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01928163
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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