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  • 1980-1984  (5)
  • 1920-1924  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 16 (1923), S. 77-83 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Durch Anwendung der Kristallgittertheorie von Born und Landé auf Mischkristalle kann man ihre Bildungswärme berechnen, wenn man ihren Gitterabstand kennt. Diese Bildungswärmen sind klein und ihr negatives Vorzeichen läßt den Zerfall der Mischkristalle mit sinkender Temperatur verstehen. Die berechneten Werte stimmen mit den experimentellen Daten dann am besten überein, wenn man die empirische Regel von der Additivität der Molekularvolumina bei der Mischkristallbildung zur Berechnung der Gitterabstände zugrunde legt.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 2 (1920), S. 299-308 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 276 (1984), S. 297-302 
    ISSN: 1432-069X
    Keywords: Psoriasis ; Selective ultraviolet phototherapy ; DNA antibodies ; Antinuclear antibodies ; ELISA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The sera of 21 psoriatics treated by selective ultraviolet phototherapy (SUP) for 1–7 months were screened for IgG- and IgM-anti-DNA antibodies and antinuclear antibodies (ANAs) by standardized ELISA and the indirect immunofluorescence technique. No patients developed IgG-antibodies against native DNA under SUP, but two patients increased their IgM-antibody titers five- and tenfold, respectively. The IgG- and IgM-anti-single-stranded-(ss)DNA antibody titers remained unaltered in 38% and 57% of the patients. In 43% and 24%, respectively, they rose to a maximum of three times their original; and in 20% they decreased to a minimum of 40% of their pretherapeutic titers. After 1 month therapy no patient had produced ANAs, but all three patients showing ANAs before therapy had increased titers (one titer step). These remained on the elevated level or were even further increased by one-titer step during progressive therapy. Two patients out of 14 developed low titers of IgM-(1:20) or IgA-(1:40)ANAs against deoxyribonucleoprotein (DNP), initially after 3 months of irradiation; in one of them IgG-ANAs (titer 1:10) against DNP were additionally formed after 6 months of therapy. Our results suggest that lesions in DNA and DNP generated by SUP trigger an immune response to nuclear antigens.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Infection 11 (1983), S. S35 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Anhand von Regressionsanalysen werden Bewertungskriterien des Ceftazidim-Agardiffusionstests mit 10 µg Disks gegeben. Mit der ICS-Methode sprechen Hemmhofdurchmesser ≥ 15 mm auf Mueller-Hinton-Agar, ≥ 17 mm auf Iso-Sensitest-Agar und ≥ 18 mm auf DST-Agar für Sensibilität (MHK ≤ 16 mg/l). Bei der Kirby-Bauer-Methode auf Mueller-Hinton-Agar sind mit diesen Disks bereits Hemmhöfe ab 12 mm als Sensibilität zu interpretieren. Die bestehenden geringen Diskrepanzen gegenüber entsprechenden Daten aus der Literatur werden auf methodische Details, insbesondere die Zusammensetzung des untersuchten Bakterien-Kollektivs zurückgeführt. Die mittleren Ceftazidim-MHK-Werte auf DST-Agar für die internationalen ReferenzstämmeEscherichia coli ATCC 25922,Staphylococcus aureus ATCC 25923 undPseudomonas aeruginosa ATCC 27853 betragen 0,25 bzw. 2,83 bzw. 1,0 mg/l.
    Notes: Summary Using regression analyses, we have determined criteria for the assessment of ceftazidime using the agar diffusion test with a 10 µg disc. With the ICS procedure, inhibition zones of ≥15 mm on Mueller-Hinton agar, ≥17 mm on Iso-sensitest agar and ≥18 mm on DST agar indicate susceptibility (MIC ≤16 mg/l). Using the Kirby-Bauer procedure, Mueller-Hinton agar and the same discs, inhibition zones of ≥12 mm indicate susceptibility. Minor discrepancies between these results and those found in the literature are due in part to differences in methodology, in particular, however, to differences in the bacteria tested. Mean MIC values for ceftazidime on DST agar were 0.25, 2.83 and 1.0 mg/l, respectively, for the international reference strainsEscherichia coli ATCC 25922,Staphylococcus aureus ATCC 25923 andPseudomonas aeruginosa ATCC 27853.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Infection 8 (1980), S. S385 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The antibacterial activity of the new antibiotic cefotaxime was compared with that of cefazolin and cefuroxime. Against 300 pathogens isolated from clinical material, cefotaxime demonstrated considerably more activity than cefuroxime, which in turn was more active than cefazolin. Cefotaxime was 37 times more active againstEnterobacter and as much as 3000 times more active againstProteus vulgaris. The growth of pseudomonads, which are resistant to cephalosporins, was inhibited by an average minimal inhibitory concentration of 10.55 mcg/ml. The regression lines of cefotaxime were derived from the results of the investigation. The equation is x=−0.40y+20.00. We obtained from this an inhibitory zone diameter for cefotaxime of ⩾23 mm at a sensitivity limit of 4 mcg/ml, and an inhibitory zone diameter of ⩽18 mm at a resistance limit of 16 mcg/ml.
    Notes: Zusammenfassung Die antibakterielle Wirksamkeit des neuen Antibiotikums Cefotaxim wurde verglichen mit der von Cefazolin und Cefuroxim. Von den 300 aus klinischem Material isolierten Erregern zeigte Cefotaxim eine wesentlich stärkere Aktivität als Cefuroxim, welches eine höhere Wirksamkeit als Cefazolin aufwies. BeiEnterobacter war Cefotaxim 37mal und beiProteus vulgaris sogar über 3000mal wirksamer. Pseudomonaden, die sich gegenüber Cephalosporinen als resistent erwiesen, wurden von Cefotaxim bei einer mittleren minimalen Hemmkonzentration (MHK) von 10,55 mcg/ml an ihrem Wachstum gehindert. Aus den Ergebnissen der Untersuchungen wurden die Regressionsgeraden für Cefotaxim ermittelt. Die Gleichung der Geraden lautet x=−0,40 y+20,00. Daraus folgt für die Empfindlichkeitsgrenze von 4 mcg/ml Cefotaxim ein Hemmhofdurchmesser von ⩾23 mm und für die Resistenzgrenze von 16 mcg/ml ein Hemmhofdurchmesser von ⩽18 mm.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary There are only slight differences between the geometrical means of minimum inhibitory concentrations of (6R,7R)-7-[(R)-2-amino-2-(p-hydroxyphenyl)-acetamido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (cefadroxil, Bidocef®) and cefalexin against gram-positive and gramnegative bacteria freshly isolated from clinical material. Enterococci are more susceptible to cefadroxil. Considering the different break points, cefadroxil is on the whole more effective than cefalexin, in particular so againstProteus mirabilis, Enterobacter, Citrobacter andEscherichia coli. With the aid of the described regression analysis a meaningful interpretation of the results of the cefadroxil agar diffusion test is possible.
    Notes: Zusammenfassung Die geometrischen Mittelwerte der minimalen Hemmkonzentrationen (MHK) von Cefadroxil ((6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)-acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo-[4.2.0] oct-2-en-2-carbonsäure, Bidocef®) und Cefalexin gegen aus klinischem Material frisch isolierte grampositive und gramnegative Bakterien differieren nur geringfügig; Enterokokken verhalten sich gegen Cefadroxil empfindlicher. Unter Berücksichtigung der unterschiedlichen „Breakpoints“ ist Cefadroxil jedoch meist wirksamer als Cefalexin, besonders beiProteus mirabilis, Enterobacter, Citrobacter undEscherichia coli. Mit der dargestellten Regressionsanalyse ist der Cefadroxil-Agar-Diffusionstest gut interpretierbar.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 2 (1983), S. 245-248 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using regression analysis to correlate MIC values and inhibition zone diameters, an attempt was made to establish criteria for interpreting the results of the agar diffusion test with norfloxacin discs (10 mcg). The test was performed on DST agar in accordance with ICS recommendations. The correlation was moderate (r=−0.8547); the regression equation was x=−0.30y + 15.80, where x was log2 MIC + 9 and y the inhibition zone diameter. The position of the MIC breakpoints of norfloxacin and the distribution of the MIC values of the bacterial population did not permit precise inhibition zone breakpoints to be established. To allow a safety margin it is recommended that for the meantime norfloxacin inhibition zones be interpreted as sensitive from 15 mm onwards.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 22 (1924), S. 126-126 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 37 (1924), S. 249-252 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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