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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 26 (1993), S. 1869-1875 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 3 (1991), S. 328-340 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A mathematical model based on the Orr–Sommerfeld equation is developed to describe the growth and suppression of multifrequency, two-dimensional instability waves in the Blasius boundary layer over a flat place through localized perturbations at the surface caused by time-varying suction/blowing. It is shown for harmonic (single-frequency) perturbations that the instability wave can be decomposed into two components: an idealized Tollmien–Schlichting wave and a second perturbation that approximately cancels the first component upstream of the surface disturbance and becomes small downstream. Because the first component alone fully expresses the instability of the flow, the need to perform numerical Fourier transformation over the wave number is eliminated, permitting easy extension of the analysis to the more general case of arbitrary waveform of the perturbation. Numerical results are presented for examples of instability-wave generation and suppression in the boundary layer.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 720 (1994), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2307
    Keywords: Cholesterol ; Foam cells ; Atherosclerosis Smooth muscle cells ; Endothelium von Willebrand factor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated whether pre-existing subendothelial smooth muscle cell (SMC) accumulations in cholesterol-fed rabbits are transformed into foam cell plaques. Twenty-four rabbits received a standard diet supplemented with 2% cholesterol for 4 or 8 weeks. Six rabbits received a supplement of 0.3% cholesterol for 35 weeks. The aorta and other systemic and pulmonary vessels were studied by immunohistochemistry for smooth muscle cells SMC (α-SMC actin), macrophages (RAM11), cell replication (proliferating cell nuclear antigen) and endothelial cells (von Willebrand factor; vWF). Initially the foam cell plaques were composed exclusively of foam cells of macrophage origin (MFC). In more advanced lesions SMC and collagen fibres were also present, leading to a fibrous transformation of the plaque. Cell replication was mainly located in the MFC. The endothelial cells covering the plaques showed an increased immunoreactivity for vWF which was also deposited in the interstitium between the FC. Pre-existing subendothelial SMC did not transform into FC. The newly formed FC plaques remained clearly separated from the pre-existing subendothelial SMC. The development of the plaques can be attributed not only to monocyte recruitment but also to macrophage multiplication.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 712-716 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Blood coagulatio and fibrinolysis were studied on 25 untrained male volunteers and on 10 highly trained athletes immediately after graduated exercise on a bicycle ergometer. We found, in particular, a shortening of the reaction time in the thrombelastogram, an accelerated thrombin formation and increased thrombin activity in the thrombin generation test, an increase of factor VIII activity, a shortening of thromboplastin times and a shortening of euglobulin lysis times in relationship to the degree of physical stress. Measurement of the three latter changes was conducted on a comparative basis between untrained subjects and highly trained athletes. Here the athletes showed lesser increases in activity as regards coagulation and fibrinolysis, in comparison to untrained persons of the same age during a standard exercise of 150 Watts. During maximal ergometer exercise the values of both test groups corresponded with one another to a large extent.
    Notes: Zusammenfassung Bei 25 untrainierten jugendlichen Versuchspersonen und 10 Hochleistungssportlern wurde das Verhalten der Blutgerinnung und Fibrinolyse während einer abgestuften Ergometerbelastung mit Hilfe verschiedener Methoden untersucht. Im einzelnen konnten eine Verkürzung der Reaktionszeit im Thrombelastogramm, eine beschleunigte Thrombinbildung und gesteigerte Thrombinaktivität im Thrombinbildungstest, eine Zunahme der Faktor VIII-Aktivität, ein Anstieg der Quick-Werte und eine Verkürzung der Euglobulin-Lysezeiten in Abhängigkeit vom Grad der körperlichen Belastung nachgewiesen werden. Die Messung der drei letztgenannten Veränderungen erfolgte vergleichend bei untrainierten Versuchspersonen und Hochleistungssportlern. Dabei zeigten die Sportler während einer Standardbelastung von 150 Watt hinsichtlich der Gerinnung und Fibrinolyse geringere Aktivitätssteigerungen als die Untrainierten gleichen Alters. Während maximaler Belastung glichen sich die Werte beider Versuchsgruppen weitgehend an.
    Type of Medium: Electronic Resource
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  • 8
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    Dordrecht : Periodicals Archive Online (PAO)
    Journal of Business Ethics. 11:2 (1992:Feb.) 89 
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 25 (1968), S. 184-197 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The submicroscopic organization of terminal chromosome regions of Drosophila hydei polytene chromosomes is described. A compact region composed of tightly packed fibrils of 100 to 125 Å diameter embedded in an amorphous material is located at each of the chromosome ends of the 5 long chromosome arms. From this compact region, sometimes containing cavities, fibrils extend onto the nearest normal band region. The diameter of the extending fibrils is 100–125 Å, 200–250 Å or 400 Å. Pronase digestion of fixed and squashed chromosomes reduced the electron density of the amorphous matrix in the compact regions but failed to affect the diameter of the fibrils. The extending fibrils, however, showed a decrease in diameter after pronase digestion. The most frequently observed diameter values were 100–125 Å. — The volume of the terminal structures, including the compact region as well as the extending fibrils, is characteristically different for the various elements of the karyotype. Chromosome 2 displays the largest terminal structure, whereas chromosome 4 only occasionally shows the presence of compact regions. — End to end association of the long chromosome arms involves the fusion of the compact terminal structures. The non-random distribution of end to end association seems to be correlated with the volume of the terminal structures. Chromosome 2 which contains the largest compact terminal region is more frequently involved in end to end associations than any other chromosome arm. — The terminal regions show replication of DNA. They belong to the group of regions which display a discontinuous labeling pattern along the chromosomes, representing a late phase of the replication cycle. — The unique structural organization of the terminal chromosome regions, which is never observed at any other location of the genome supports the idea that they are morphological manifestations of the postulated telomeres.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 88 (1992), S. 204-212 
    ISSN: 1432-1106
    Keywords: Cerebral cortex of man ; Morphology of white matter neurons ; Subplate cells ; Golgi method ; Immunohistochemistry ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurons in the human cerebral cortical white matter below motor, visual, auditory and prefrontal orbital areas have been studied with the Golgi method, immunohistochemistry and diaphorase histochemistry. The majority of white matter neurons are pyramidal cells displaying the typical polarized, spiny dendritic system. The morphological variety includes stellate forms as well as bipolar pyramidal cells, and the expression of a certain morphological phenotype seems to depend on the position of the neuron. Spineless nonpyramidal neurons with multipolar to bitufted dendritic fields constitute less than 10% of the nuerons stained for microtubule associated protein (MAP-2). Only 3% of the MAP-2 immunoreactive neurons display nicotine adenine dinucleotide-diaphorase activity. The white matter pyramidal neurons are arranged in radial rows continuous with the columns of layer VI neurons. Neuron density is highest below layer VI, and decreases with increasing distance from the gray matter. White matter neurons are especially abundant below the primary motor cortex, and are least frequent below the visual cortex area 17. In contrast to other mammalian species, the white matter neurons in man are not only present during development, but persist throughout life.
    Type of Medium: Electronic Resource
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