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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 11 (1955), S. 179-180 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Untersuchung der Carotinoide aus den Äzidien des RostpilzesGymnosporangium juniperi-virginianae Schw. ergab das Vorliegen von 66,5%γ-Carotin und 33,5%β-Carotin (Durchschnittswerte). Diese Werte stimmen mit denjenigen anderer Autoren für Teleuto-Stadium und Pyknidenform überein. Art und Mengenverhältnis der Carotinoide in drei Stadien vonGymnosporangium juniperi-virginianae Schw. (auf verschiedenen Wirtspflanzen) sind daher ungefähr identisch.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 77 (1955), S. 489-490 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 69 (1991), S. 220-223 
    ISSN: 1432-1440
    Keywords: Human Anti-Mouse-Antibodies ; TSH-IRMA ; Monoclonal antibody therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Monoclonal murine antibodies are increasingly used for immunotherapy and in vivo diagnostic procedures such as immunoscintigraphy. The therapeutic or diagnostic reagent however, is a foreign antigen, which may induce host reactivity. This may interfere with the therapeutic or diagnostic reagent in vivo, resulting in a loss of efficacy or the necessity to increase dosages. In addition, there is an important interference to in vitro immunoassays detecting specific antigens utilizing murine monoclonal antibodies. In the present study, sera of patients who had undergone a therapeutic trial using 140 mg of an anti-CD4 antibody, were investigated. Human anti-murine-immunoglobulin-antibodies (HAMA) were detected 2–3 weeks after treatment was started and reached maximal amounts of 0.8 μg/ml after a single and 2 μg/ml after a repeated treatment course. Parallely raised values of TSH were found in sera containing HAMAs of more than 0.3 μg/ml. Elevations of TSH levels up to 13 μU/ml were most pronounced after a repeated trial of the murine antibody and were detectable up to 20 weeks.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-0879
    Keywords: High-energy shock waves ; Human kidney ; Side effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Between September 1990 and July 1991, we treated 17 patients with renal-cell carcinoma by radical nephrectomy and two patients with urothelial carcinoma of the kidney pelvis by ureteronephrectomy. Immediately after nephrectomy, perfusion of the kidneys with cold HTK solution was performed and the organs were kept in hypothermia of 8°C. The tumor-free parenchyma of the kidneys was treated 4 h later with shock waves of different energy levels in an experimental shock-wave system (Siemens Company, Erlangen). Light microscopy and examinations by scanning laser microscopy were performed after treatment. High-energy shock waves (HESW) produce significant changes in the tubulary and blood-vessel system of the viable human kidney, depending on the energy applied. Although our model is limited by hypothermia of the explanted kidneys, the effects of shock waves on the organs can be studied. Our model is suitable for testing the effects of different lithotriptors on the human kidney.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 70 (1994), S. 525-531 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract. The representations of visual hemifields in the extrastriate areas of various species exhibit field discontinuities and islands. We propose that these violations of retinotopy are a developmental consequence of the elongated shape of the respective cortical areas. To substantiate this claim, we investigated a model of activity-driven map formation. In agreement with observations, this model yields maps with field discontinuities if the cortical areas exceed a threshold elongation. Moreove r, within the same model island representations in the periphery and the area centralis can also be understood. A multistability of the solutions in the model gives a very simple explanation for the observed interindividual variability of maps in cats. The model leads to a prediction of the radial dependence of the areal magnification factor near field discontinuities, which could be accessible for a high precision mapping experiment.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 70 (1994), S. 525-531 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract The representations of visual hemifields in the extrastriate areas of various species exhibit field discontinuities and islands. We propose that these violations of retinotopy are a developmental consequence of the elongated shape of the respective cortical areas. To substantiate this claim, we investigated a model of activity-driven map formation. In agreement with observations, this model yields maps with field discontinuities if the cortical areas exceed a threshold elongation. Moreover, within the same model island representations in the periphery and the area centralis can also be understood. A multistability of the solutions in the model gives a very simple explanation for the observed interindividual variability of maps in cats. The model leads to a prediction of the radial dependence of the areal magnification factor near field discontinuities, which could be accessible for a high precision mapping experiment.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 120 (1994), S. 439-441 
    ISSN: 1432-1335
    Keywords: Adhesion ; DNA ; Flow cytometry ; Ki67 ; Lithotripsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Multicellular tumor spheroids (MCTS) grown from the bladder cancer cell line RT112 and from the prostate cancer cell line PCA were exposed to 200 or 800 electromagnetically generated focused ultrasound shock waves. RT112 cells showed a distinct but transient decrease in proliferation whereas the effect of PCA cells was less pronounced. Flow-cytometric measurements of DNA content and Ki67 expression revealed no significant changes in the cell cycle distribution. The capacity of RT112 cells exposed to 800 shock waves to re-grow as MCTS was markedly decreased, indicating an alteration of intercellular adhesion.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Lung 120 (1959), S. 170-185 
    ISSN: 1432-1750
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: The effect of the bead diameter on the accuracy of two techniques used in bone ingrowth quantification, microradiography and backscattered electron imaging-scanning electron microscopy (BEI-SEM), was assessed using porous-coated implants. Two groups of seven titanium porous implants (group A: bead size 250–350 μm and group B: 500–700 μm) were implanted for 12 weeks in a canine model. After euthanasia, the same histological slides were prepared for microradiography and BEI-SEM. The percentage of bone, bone ingrowth, bone ongrowth, porosity and bone index were determined by a point counting method using images from both techniques. ANOVA and Tukey's test were used to compare the results from the different bead sizes and techniques. The results showed significant higher bone ingrowth in microradiography groups, and significant lower porosity in only the fine-bead microradiography group (group A size). Microradiography also obtained significantly higher bone ongrowth, but only for the coarse bead size group (group B). From these results it was concluded that microradiography decreases the porosity of the porous coating compared with BEI-SEM. This effect seems to be dependent on the bead diameter. The smaller the diameter, the greater the effect. Furthermore, microradiography increases bone ingrowth which seems to be affected independently of the bead diameter, becoming the most sensitive parameter to increase.
    Type of Medium: Electronic Resource
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