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  • 1990-1994  (5)
  • Engineering General  (2)
  • Serratia marcescens  (2)
  • 3,4-dihydroxyphenylacetic acid  (1)
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  • 1990-1994  (5)
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    L-threo-3,4-dihydroxyphenylserine, a noradrenaline precursor, inhibits dopamine release and metabolism in the rat striatum in vivo (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 1133-1134 
    Details
    ISSN: 1420-9071
    Schlagwort(e): In vivo microdialysis ; striatum ; noradrenaline ; L-threo-3,4-dihydroxyphenylserine ; dopamine release ; 3,4-dihydroxyphenylacetic acid ; homovanillic acid ; high performance liquid chromatography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract The effect of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) on dopamine (DA) release and metabolism in the striatum was studied in freely moving rats by intracerebral microdialysis techniques. The DA level as well as the levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid were significantly decreased 140 min after the administration of L-threo-DOPS (50 mg/kg intraperitoneally). The results suggest that L-threo-DOPS inhibits the release and metabolism of DA in the striatum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01948006
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  • 2
    Digitale Medien
    Digitale Medien
    Increased renal scarring by bacteria with mannose-sensitive pili (1990)
    Springer
    Urological research 18 (1990), S. 299-303 
    Details
    ISSN: 1434-0879
    Schlagwort(e): MS pili ; Serratia marcescens ; Renal scarring
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Renal scars are thought to be the end stage of chronic pyelonephritis and one of the most important causes of renal insufficiency and renal hypertension. The role of bacterial pili was examined in scar formation after an infection of newly constructed bacterial strains using the recombinant DNA technique, which possessed either mannose resistant (MR) or mannose sensitive (MS) pili of Serratia marcescens. Strains that differed in only a single virulence factor, namely, MR or MS pili, were used in a rat model of chronic pyelonephritis. In this model, MS-piliated bacteria stimulated renal scarring more severely than non-piliated or MR-piliated bacteria.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00300774
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  • 3
    Digitale Medien
    Digitale Medien
    Role of superoxide in renal scarring following infection by mannose-sensitive piliated bacteria (1991)
    Springer
    Urological research 19 (1991), S. 229-233 
    Details
    ISSN: 1434-0879
    Schlagwort(e): Pyelonephritis ; Renal scarring ; Pathogenesis ; Serratia marcescens ; Piliation ; Superoxide dismutase ; Leukocytes
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The role of superoxide in scar formation following renal infection caused by mannose-sensitive (MS) piliated strains of bacteria was studied in the experimental pyelonephritis model using female Sprague-Dawley rats. The MS piliated strain stimulated renal scarring to a significantly greater extent than either the non-piliated or MR-piliated strain. Modulation of leukocytes by administering cyclophosphamide to induce neutropenia and colchicine to inhibit leukocyte migration was effective in preventing renal scarring. Treatment with superoxide dismutase during the early stage of infection was also effective in preventing scar formation. Finally, the production of superoxide by rat leukocytes was significantly larger following stimulation by MS piliated than either the nonpiliated or MR piliated strains. These observations suggest that superoxide released from leukocytes plays a critical role in the development of renal scarring following a bacterial infection, especially by MS piliated strains.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00305300
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  • 4
    Digitale Medien
    Digitale Medien
    Boundary-element solution of some structural-acoustic coupling problems using the multiple reciprocity method (1994)
    Chichester : Wiley-Blackwell
    Communications in Numerical Methods in Engineering 10 (1994), S. 237-248 
    Details
    ISSN: 1069-8299
    Schlagwort(e): Engineering ; Engineering General
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Mathematik , Technik allgemein
    Notizen: In the paper we have developed a new formulation for solution of structural-acoustic coupling problems by boundary elements using the multiple reciprocity method. It is assumed that the structure is composed of plate components and is excited by the external or the internal noise source. The efficiency of the proposed formulation becomes especially remarkable if the boundary-value problem is to be solved repeatedly for different values of frequency. The accuracy of the numerical computations has been compared with the analytical solution in a test example.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cnm.1640100307
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  • 5
    Digitale Medien
    Digitale Medien
    Regularization of hypersingular and nearly singular integrals in the potential theory and elasticity (1993)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 36 (1993), S. 1609-1628 
    Details
    ISSN: 0029-5981
    Schlagwort(e): Engineering ; Engineering General
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Mathematik , Technik allgemein
    Notizen: Both the hypersingular and nearly singular integrals, which appear in the hypersingular boundary integralequations and integral representations of the secondary fields, respectively, are regularized by the application of the superposition principle. Two kinds of the non-singular formulations, namely, those with the strongly singular and weakly singular kernels, are presented in this paper. The formulations are given in terms of the relevant boundary quantities and the collocation at element junctions is possible. Two- and three-dimensional problems are analysed simultaneously in a unique way for either internal or external problems of the potential theory and elasticity.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/nme.1620361002
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