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  • 1990-1994  (6)
  • Abnormal tau  (2)
  • 36.40. + d  (1)
  • Alzheimer's disease  (1)
  • Arachnoid villi  (1)
  • Brain abscess  (1)
  • Cerebritis  (1)
Source
Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Immunohistochemical expression of glutathione S-transferase placental type (GST-π), a detoxifying enzyme, in normal arachnoid villi and meningiomas (1990)
    Springer
    Virchows Archiv 417 (1990), S. 493-496 
    Details
    ISSN: 1432-2307
    Keywords: Arachnoid villi ; Meningioma ; Glutathione S-transferase placental type ; Cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Human normal dura mater containing arachnoid villi were examined for their expression of glutathione S-transferase placental type (GST-π), a detoxifying enzyme, using an immunohistochemical method. All of the arachnoid villi and arachnoid cells in five normal cases were found to have expression of GST-π, although no positive reaction for the enzyme was present in other tissues of the dura mater. The results show a possible role for arachnoid tissues in protecting human brain from hazardous xenobiotics in the cerebrospinal fluid. Twenty-six meningiomas were also examined for expression of the enzyme. Tissues of meningotheliomatous meningiomas were always positive for expression of the enzyme. Transitional meningiomas also showed the expression in their meningotheliomatous components. No staining reaction of GST-π was recognized in fibroblastic meningiomas except for two cases with a tendency to meningotheliomatous differentiation. The findings suggest a functional similarity between the arachnoid tissues and meningotheliomatous components of meningiomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01625729
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Senile dementia of Alzheimer type characterized by laminar neuronal loss exclusively in the hippocampus, parahippocampus and medial occipitotemporal cortex (1990)
    Springer
    Acta neuropathologica 80 (1990), S. 575-580 
    Details
    ISSN: 1432-0533
    Keywords: Senile dementia of Alzheimer's type ; Alzheimer's disease ; Pick's disease ; Laminar neuronal loss ; Limbic system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Seven cases of senile dementia of Alzheimer type (SDAT) with unusual clinico-pathological findings are reported. The patients showed neuronal loss in laminar pattern, with gliosis exclusively confined to the CA1 of the hippocampus, the area of the hippocampal gyrus (entorhinal cortex) and medial occipitotemporal cortex. This change was more pronounced in the oral region. The subcortical white matter showed more pronounced fibrillary gliosis than loss of myelin. Both Alzheimer's neurofibrillary tangles and senile plaques were less marked than those usually seen in SDAT. The mental disturbance started after the age of 65 in all patients. The main clinical feature was marked character change in addition to disturbance of cognitive function. Cranial computed tomography showed marked dilatation of the oral portion of the inferior horn of the lateral ventricle in the early stage. It was apparent that although the cases in this group could be incorporated within in the spectrum of SDAT, they could also be considered to represent a variant of SDAT. This group could contribute to an understanding of the clinico-pathological spectrum of SDAT as well as indicating ways of managing such patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307623
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Keywords: Corticobasal degeneration ; Progressive supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294503
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Keywords: Key words: Corticobasal degeneration ; Progressive ; supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294503
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Serial neuroradiological studies in focal cerebritis (1994)
    Springer
    Neuroradiology 36 (1994), S. 285-288 
    Details
    ISSN: 1432-1920
    Keywords: Cerebritis ; Brain abscess ; MRI ; CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report serial neuroradiological studies in a patient with focal cerebritis in the head of the left caudate nucleus. On the day after the onset of symptoms, CT showed an ill-defined low density lesion. The lack of contrast enhancement appeared to be the most important finding for differentiating focal cerebritis from an encapsulated brain abscess or a tumour. MRI two days later revealed the centre of the lesion to be of slightly low intensity on T1-weighted inversion recovery (IR) images and very low intensity on T2-weighted spin echo images, which appeared to correspond to the early cerebritis stage of experimentally induced cerebritis and brain abscess. Ten days after the onset of symptoms, CT revealed a thin ring of enhancement in the head of the caudate nucleus, and a similar small ring was seen in the hypothalamus 16 days after the onset, corresponding to the late cerebritis stage. MRI nine days later revealed ill-defined high signal lesions within the involved area on the T1-weighted IR images. To our knowledge, this is the first published MRI documentation of the early cerebritis stage developing into an encapsulated brain abscess. The mechanisms underlying of these radiographic changes are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593261
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Structure of nm-sized InSb clusters formed by spontaneous alloying (1994)
    Springer
    The European physical journal 31 (1994), S. 209-212 
    Details
    ISSN: 1434-6079
    Keywords: 61.16.Di ; 36.40. + d ; 66.30. − h
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The alloying behavior of antimony atoms into nm-sized indium clusters has been studied in situ by TEM. When antimony atoms are vapor-deposited onto nm-sized indium clusters, a rapid dissolution of antimony atoms into indium clusters takes place and as a result InSb compound clusters are successfully formed. Such spontaneous alloying occurs even at ambient temperature. InSb clusters thus formed have the wurtzite structure. When these InSb clusters are annealed at 533 K, their structure changes into the sphalerite structure, which is the structure of the equilibrium phase of the bulk In50Sb50. The appearance of wurtzite-type InSb by spontaneous alloying is discussed in terms of ionicity of bonds in InSb.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01437838
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    Paper (German National Licenses)
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