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  • 11
    Electronic Resource
    Electronic Resource
    Codon 12 Harvey-ras mutations are rare events in non-melanoma human skin cancer (1993)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 128 (1993), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: ras mutations have been reported as an early event in some human malignancies and in the mouse skin model of multistep carcinogenesis; early studies in human non-melanoma skin cancers have reported variable rates of ras mutations. A recent study, however, has reported a high frequency of activating mutations of the Harvey-ras proto-oncogene in non-melanoma skin cancers, and the site specificity of the mutation at the second position of codon 12 prompted us to re-examine the importance of Ha-ras codon 12 mutations as an early event in the development of these tumours, using a combination of PCR and restriction fragment polymorphism of codon 12 of the Ha-ras gene. Dilution experiments confirmed that the method was sensitive and capable of detecting mutations at this codon when only 4% of the total alleles are mutated. We were surprised to find no mutations in the 40 basal cell carcinomas. 12 squamous cell carcinomas and 12 cases of Bowen's disease studied. We conclude that Ha-ras codon 12 mutations are rare events in human non-melanoma skin cancer in the U.K. The marked differences in the frequency of codon 12 Ha-ras mutations in published studies may relate to either technical artefacts, or differences in the molecular epidemiology between areas of low and high sun exposure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1993.tb15137.x
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  • 12
    Electronic Resource
    Electronic Resource
    Structures of three 1-[(diphenylphosphinoyl)methyl]cyclohexanols (1992)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 48 (1992), S. 690-693 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270191010430
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  • 13
    Electronic Resource
    Electronic Resource
    The thermal polymerisation of a diacetylenic liquid crystal (1992)
    Springer
    Polymer bulletin 29 (1992), S. 661-668 
    Details
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary In this paper, the polymerisation of a conjugated liquid crystalline diacetylene is reported. The structure of the polymer is discussed in relation to results from spectroscopic studies and molecular weight determinations. The polymer has a backbone structure analogous to that of other polydiacetylenes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01041152
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  • 14
    Electronic Resource
    Electronic Resource
    Response of Phorodon humuli to yellow and to green hop foliar colours (1991)
    Springer
    Entomologia experimentalis et applicata 60 (1991), S. 95-99 
    Details
    ISSN: 1570-7458
    Keywords: Aphididae ; Phorodon humuli ; host selection ; foliar colour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00164963
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  • 15
    Electronic Resource
    Electronic Resource
    Pseudomicrodochium fusarioides sp. nov., isolated from human bronchial fluid (1991)
    Springer
    Mycopathologia 114 (1991), S. 159-161 
    Details
    ISSN: 1573-0832
    Keywords: Pseudomicrodochium ; phaeohyphomycosis ; lung isolate ; new species
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A fungus from bronchial lavage fluid from a patient with pulmonary infiltration was isolated in pure culture and identified as a species of Pseudomicrodochium. It is compared and contrasted with other species of the genus, in particular P. suttonii, and formally described as P. fusarioides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00437207
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  • 16
    Electronic Resource
    Electronic Resource
    C2 rotation and spinous process deviation in migraine: cause or effect or coincidence? (1991)
    Springer
    Neuroradiology 33 (1991), S. 475-477 
    Details
    ISSN: 1432-1920
    Keywords: Migraine ; Computed tomography ; Cervical spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Previous reports have shown an association between the side of C2 spinous process deviation or asymmetrical prominence, or vertebral rotation, and the side of the headache in unilateral migraine. However, this study has found that such C2 appearances were present as frequently in the controls as in the migraine patients, and that there was no association between the side of the anomaly and the lateralisation of the headache. The results were comparable for the different sub-groups of migraine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588037
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  • 17
    Electronic Resource
    Electronic Resource
    Thermal and optical studies on some monomer and polymer diacetylenes (1990)
    Springer
    Journal of thermal analysis and calorimetry 36 (1990), S. 1669-1674 
    Details
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Es werden thermische und optische Studien einiger Diacethylene beschrieben, die zwecks der Senkung der Temperatur für das Auftreten von Mesophasen eigens gestaltet wurden. Ursprüngliche Untersuchungen an symmetrischen Molekülen wurden erweitert, um auch typische Flüssigkeitskristallmoleküle mit Diacethylenen mit Polymerhauptketten und unsymmetrisch substituierte Diacethylene wie Schiff-Basen mit langen Alkylketten einzubeziehen.
    Notes: Abstract We describe the thermal and optical studies of some diacetylene molecules which were specially designed in an attempt to reduce the temperature at which the mesophase appears. Original studies were on symmetrical molecules and these were extended to include typical liquid crystal molecules with diacetylenes providing a polymeric backbone and unsymmetrically substituted diacetylenes including Schiffs bases with long alkyl chains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01913413
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  • 18
    Electronic Resource
    Electronic Resource
    Sex attractant pheromone of damson-hop aphid Phorodon humuli (Homoptera, aphididae) (1990)
    Springer
    Journal of chemical ecology 16 (1990), S. 3455-3465 
    Details
    ISSN: 1573-1561
    Keywords: Pheromone ; sex ; attractant ; aphid ; Phorodon humuli ; Homoptera ; Aphididae ; nepetalactol ; monoterpenoid ; electrophysiology ; single cell recording ; mass spectrometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Behavioral studies using an olfactometer demonstrated that sexual females (oviparae) of the damson-hop aphid,Phorodon humuli, release a pheromone to which males respond. Volatiles produced by the oviparae were analyzed by coupled gas chromatography-single cell recording from the secondary rhinaria on the male antenna and showed the presence of one peak with major activity. Coupled gas chrornatography-mass spectrometry suggested a nepetalactol, which was shown to have the 4aR, 7S, 7aS stereochemistry by synthesis from the corresponding nepetalactone isolated from the labiate plantNepeta mussinii. Although the stereochemistry at carbon-1 is not yet established, a synthetic sample comprising ca. 70% 1S and 30% 1R attracted highly significant numbers of males to water traps placed within and adjacent to a hop garden. Initial studies also indicated attraction of males in both the olfactometer and in the field by volatiles from the primary host.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00982110
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  • 19
    Electronic Resource
    Electronic Resource
    Impulse strengths in rapid granular shear flows (1994)
    Springer
    Acta mechanica 104 (1994), S. 65-90 
    Details
    ISSN: 1619-6937
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary This paper describes measurements of the impulses that particles experience while undergoing rapid shear. These were performed with an eye towards understanding the processes that lead to particle attrition and fracture. The measurements were taken from a discrete particle computer simulation of a simple shear flow of spheres. Special attention is paid to the strongest impulses as these will do the most damage. The results indicate that the largest impulses arise, not from the mean shear flow, but from the random particle velocities that are characterized by the so-called “granular temperature”. Measurements of the largest impulses are presented as functions of particle properties and solid concentration. Histograms of the impulse strengths illustrate the effect of concentration and particle surface friction. Finally, geometric distributions are presented that illustrate the shear induced anisotropy in the impulse strengths.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01170277
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  • 20
    Electronic Resource
    Electronic Resource
    Remnants of Bose condensation and off-diagonal long range order in finite systems (1993)
    Springer
    Journal of low temperature physics 93 (1993), S. 907-919 
    Details
    ISSN: 1573-7357
    Keywords: 67.40.-w ; 67.40.Db ; 05.30.Jp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We briefly review some general aspects of Bose condensation and off-diagonal long range order in infinite bulk systems and then discuss to what extent these features might be manifested in finite systems with free surfaces such as droplets of liquid 4 He at low temperatures. We focus on the structure of the one-body density matrix and the macroscopic wave function in the surface region, and note the possibility of a surface condensate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00692038
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