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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 57 (1985), S. 5438-5442 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The spectral distribution of photoconductivity and infrared excited electroluminescence has been determined in GaP light emitting diodes at low temperatures by conventional infrared spectroscopic techniques. The observed photoresponse was found to be caused by ionization of shallow donors only, showing a peak sensitivity of 20 mA/W at 13-μm wavelength. Spectral structures for photon energies lower than the binding energies of shallow donors are attributed to electric field assisted photoionization. An external quantum efficiency of 3×10−3 was obtained being largely independent on the bias voltage and the wavelength of infrared stimulation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 464 (1986), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 119 (1988), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 86 (1929), S. 382-425 
    ISSN: 1433-8491
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 66 (1988), S. 790-795 
    ISSN: 1432-1440
    Keywords: Breast cancer ; Lung metastases ; Clinical course
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical course of 50 breast cancer patients whose first metastases were found in the lungs was investigated. 18 months after the start of primary treatment 50% of the patients had developed pulmonary metastases (range: 0–81 months). In 23% of patients a solitary, and in 68% more than one, lung metastases were detected. After a median time of 4 months, in 56% of patients the disease had spread to further organs with bone (25%) and liver (17%) being the most frequent sites. First line management of lung metastases employed surgery, endocrine treatment, chemotherapy or a combination of these modalities. In 24% of patients a complete response was achieved, and in 11% a partial response, with an overall response rate of 35%. Median survival from detection of lung metastases was 13 months (range 4–123+). Patients with only a solitary lung metastasis survived for a median of 11.5 months as compared to 10.5 months for patients with more than one pulmonary metastases. Patients with a disease-free interval of more than 18 months survived significantly longer than patients with a disease-free survival of 18 months or less.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 67 (1989), S. 813-817 
    ISSN: 1432-1440
    Keywords: Tumor marker ; MCA ; CA 15-3 ; Breast cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Mucin-like cancer-associated antigen (MCA), a new tumor marker using the mouse monoclonal antibody b-12 is thought to be of value in the management of patients with breast cancer. In this study sera from 191 female patients with breast cancer (112 with progressive disease [PD] and 79 with no evidence of disease [NED]) were analyzed for MCA levels and compared with those of cancer antigen 15-3 (CA 15-3) in single determination and in combination with carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA). A cut-off level of 14 U/ml for MCA seems to be more appropriate than the recommended 11 U/ml to distinguish between PD and NED in patients with breast cancer. Although there was a fairly good correlation of MCA to CA 15-3, MCA was inferior in sensitivity and specificity to CA 15-3. Patients with osseous metastases and those with more than one metastatic site showed higher MCA levels than patients with visceral or soft tissue metastases, a fact which was comparable to CA 15-3. Combining MCA and CA 15-3 resulted in a gain in specificity but marked loss of sensitivity. The combination of MCA and CEA results also in a loss of sensitivity whereas the combination of CA 15-3 and CEA showed an increased specificity and only a negligible loss of sensitivity. The combination of MCA with TPA is of little value in the follow-up of breast cancer, as is the combination of CA 15-3 with TPA. The combination of CA 15-3 with CEA can be still recommended for follow-up for early detection of metastases in breast cancer. Further investigations with MCA to determine the lead time of this new marker as well as its role as a possible monitor of the response to therapy are recommended.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 158 (1972), S. 288-297 
    ISSN: 1433-8580
    Keywords: Oxyfedrin ; Propranolol ; Hemodynamics ; Myocardial metabolism ; Hepatic metabolism ; Oxyfedrin ; Propranolol ; Hämodynamik ; Herzstoffwechsel ; Leberstoffwechsel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Trotz vorheriger Gabe von Propranolol bewirkt Oxyfedrin beim Hund einen signifikanten Anstieg der Frequenz, des arteriellen Spiegels der freien Fettsäuren, der arteriellen 3-Hydroxybutyrat-Konzentration und der Aufnahme von freien Fettsäuren in die Leber sowie eine ebenfalls statistisch gesicherte Verminderung des coronaren Widerstandes. Ein Vergleich der gefundenen Wirkungen mit bereits publizierten Ergebnissen zeigt dennoch eine, wenn auch nur partielle Blockierbarkeit der Oxyfedrineffekte durch Propranolol. Die anderen, z. T. gegenüber der alleinigen Gabe von Oxyfedrin sogar verstärkten Wirkungen wie die signifikante Abnahme des arteriellen Spiegels und der myokardialen Bilanz von Pyruvat werden durch gleichsinnige, additive Wirkungen von Propranolol und Oxyfedrin erklärt.
    Notes: Summary Following beta-adrenergic blockade with propranolol, infusions with oxyfedrin caused significant increases in heart rate, arterial free fatty acids and 3-hydroxy-butyrate levels, uptake of free fatty acids into the heart and liver, and a significant decrease in coronary vascular resistance. A comparison with data from previous experiments without beta-adrenergic blockade shows at least a partial blockade of the hemodynamic and metabolic effects caused by oxyfedrin. The other metabolic parameters, showing identical changes with oxyfedrin and propranolol, could not be taken for a comparison of the action of oxyfedrin before and after betaadrenergic blockade.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 162 (1974), S. 341-346 
    ISSN: 1433-8580
    Keywords: Fructose ; Purine synthesisde novo ; Adenine nucleotides ; Rat liver ; Rat muscles ; Hyperuricemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The intravenous infusion of fructose (0.7 and 2.4 g/kg/30 min) increases the incorporation of14C-glycine into rat liver adenine nucleotides significantly as compared to controls treated with 0.9% NaCl. A decrease of the total adenine nucleotide content of the livers occurs concomitantly. In contrast to its effect upon liver tissue fructose neither effects the content of adenine nucleotides nor the incorporation of glycine into these nucleotides in skeletal muscle of rats. — The results support the hypothesis that large quantities of fructose cause an increasedde novo synthesis of purine nucleotides in the liver. However, they do not as yet present clear cut evidence as to whether this is a direct effect of fructose or is secondary to the depletion of adenine nucleotides.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 81 (1927), S. 584-594 
    ISSN: 1433-8491
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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