ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A 13-year-old male pseudohermaphrodite (mixed gonadal dysgenesis, unilateral testicular differentiation) was found to be a chromosomal mosaic of the 45, XO/46, XY type, the Y chromosome being a symmetrical dicentric chromosome. Presumed Y chromosomes similar to this one have been observed before, but their identification was not supported by autoradiographic data. In the present study the identification of the dicentric as a Y chromosome was supported by observing a relatively late DNA replication during the S period. The differentiation of testicular tissue on one side may be related to the presence of short arm material of the Y chromosome in the genome of the XY dic cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00297721
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