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  • 1
    Electronic Resource
    Electronic Resource
    Histidase and urocanase activities of liver and plasma. Correlations between tissue enzyme levels and plasmatic increases during human and mouse viral hepatitis
    Amsterdam : Elsevier
    Clinica Chimica Acta 13 (1966), S. 568-573 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(66)90160-4
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  • 2
    Electronic Resource
    Electronic Resource
    ENVIRONMENTAL INFLUENCES ON EATING AND PHYSICAL ACTIVITY (2001)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Public Health 22 (2001), S. 309-335 
    Details
    ISSN: 0163-7525
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Notes: Abstract Obesity has increased dramatically over the past two decades and currently about 50% of US adults and 25% of US children are overweight. The current epidemic of obesity is caused largely by an environment that promotes excessive food intake and discourages physical activity. This chapter reviews what is known about environmental influences on physical activity and eating behaviors. Recent trends in food supply, eating out, physical activity, and inactivity are reviewed, as are the effects of advertising, promotion, and pricing on eating and physical activity. Public health interventions, opportunities, and potential strategies to combat the obesity epidemic by promoting an environment that supports healthy eating and physical activity are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.publhealth.22.1.309
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  • 3
    Electronic Resource
    Electronic Resource
    Peripheral arterial pulse wave analysis in women with pre-eclampsia and gestational hypertension (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective  To compare peripheral pulse pressure waveforms in normal pregnancy, gestational hypertension (GH) and pre-eclampsia (PE).Design  Comparative study.Setting  Tertiary referral teaching hospital.Sample  Women with hypertensive disease in pregnancy and matched normal pregnant controls.Methods  Women in the third trimester of pregnancy with newly developed PE (n= 27) or GH (n= 33) were studied by radial artery applanation tonometry. Values were compared with those for gestational age matched normal pregnant women (n= 39).Main outcome measures  Augmentation Index.Results  Hypertension was of equal severity in PE and GH. Central augmentation pressure and augmentation index, indicating vasoconstriction, were mildly elevated in GH, but markedly elevated in PE.Conclusion  Non-invasive applanation tonometry discriminates among normal pregnancy, GH and PE, and may be useful to predict PE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2005.00701.x
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  • 4
    Electronic Resource
    Electronic Resource
    Upregulation of muscarinic receptors by long-term nitric oxide inhibition in the rat ileum (2003)
    Oxford, UK : Blackwell Science Pty
    Clinical and experimental pharmacology and physiology 30 (2003), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The aim of the present study was to examine the effects of long-term nitric oxide (NO) blockade on contractions of the rat ileum induced by muscarinic agonists.2. Male Wistar rats received the NO synthesis inhibitor NG-nitro-l-arginine methyl ester (l-NAME; 20 mg/rat per day) in drinking water for 7, 15, 30 and 60 days. Concentration–responses curves to methacholine and carbachol were obtained and pEC50 values were calculated. Saturation binding assays were performed in membranes prepared from rat ileum after 60 days of l-NAME treatment and the dissociation constant (KD) and maximal number of binding sites (Bmax) were determined by Scatchard analysis.3. The NO synthase activity of the ileum was markedly reduced in all l-NAME-treated groups. At 60 days after l-NAME treatment, a significant increase in the potency of methacholine (fourfold) and carbachol (threefold) was observed. In binding studies, we found a significant increase in Bmax for [3H]-quinuclidinyl benzilate of approximately 57% in the l-NAME treated group without any significant change in KD values. The contractile response to methacholine was not modified by the soluble guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one (3 µmol/L). No morphological alterations in the rat ileum were observed in l-NAME-treated rats.4. Our findings suggest that treatment with l-NAME for 60 days induces a marked increase in the potency of methacholine and carbachol, as well as an increase in receptor number in the rat ileum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1440-1681.2003.03807.x
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  • 5
    Electronic Resource
    Electronic Resource
    Maternal defence as an emotional stressor in female rats: correlation of neuroendocrine and behavioural parameters and involvement of brain oxytocin (2001)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 13 (2001), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In order to study neuroendocrine and behavioural stress responses in female rats post partum we aimed to establish a relevant emotional stressor – the maternal defence test based on maternal aggression of a lactating resident towards a virgin or lactating intruder approaching the cage. Exposure to maternal defence significantly elevated corticotropin (ACTH) and corticosterone responses of the residents and of virgin or lactating intruders, with an attenuated response in lactating residents and lactating intruders. Exposure to maternal defence increased plasma oxytocin in virgin intruders only. The aggressive behaviour displayed by the residents was directly correlated with the amount of defensive behaviour of the intruder and independent of the intruder's reproductive state. However, the amount of maternal and explorative behaviours displayed by the lactating residents was significantly higher when exposed to a lactating, compared to a virgin, intruder. ACTH responses in lactating residents exposed to virgin intruders were significantly correlated to the amount of offensive (direct correlation) and maternal (inverse correlation) behaviours they displayed. Plasma prolactin concentrations, elevated in lactating compared to virgin rats under basal conditions, were found to be reduced in the lactating residents and intruders in response to exposure to the maternal defence test, whereas it was unchanged in virgin intruders. To test for the involvement of brain oxytocin in neuroendocrine and behavioural responses of the lactating residents an oxytocin receptor antagonist (0.1 µg/5 µL) was infused icv 10 min prior to testing. This treatment increased basal, but not stress-induced, ACTH, corticosterone and oxytocin secretion. Whereas parameters of aggressive behaviour were unchanged, the antagonist reduced signs of maternal behaviour during maternal defence. In summary, the maternal defence test has been characterized as a relevant emotional stressor for female rats which is useful for studying neuroendocrine and emotional responses in females, in particular in the context of reproductive adaptations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0953-816x.2001.01460.x
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  • 6
    Electronic Resource
    Electronic Resource
    Characterization of the ionizing radiation sensitivity of a CCD technology
    Amsterdam : Elsevier
    Microelectronic Engineering 19 (1992), S. 609-612 
    Details
    ISSN: 0167-9317
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-9317(92)90507-N
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  • 7
    Electronic Resource
    Electronic Resource
    Michael-type addition of phthalimide salts to chiral α,β-unsaturated imides
    Amsterdam : Elsevier
    Tetrahedron Letters 35 (1994), S. 5051-5054 
    Details
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(00)73317-X
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  • 8
    Electronic Resource
    Electronic Resource
    Giant aneurysm of the calloso-marginal artery (1991)
    Springer
    Child's nervous system 7 (1991), S. 353-355 
    Details
    ISSN: 1433-0350
    Keywords: Intracranial aneurysm ; Giant aneurysm ; Distal anterior cerebral artery aneurysm ; Childhood vascular disease ; Aneurysmal tumor ; False aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A giant aneurysm of the right callosomarginal artery is reported in a 3-month-old child. This location is rare: including our case reported here, only three cases have been described. Clinicoradiological findings are presented and the surgical procedure is illustrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304836
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  • 9
    Electronic Resource
    Electronic Resource
    A male pseudohermaphrodite with a dicentric Y chromosome (1968)
    Springer
    Human genetics 〈Berlin〉 6 (1968), S. 131-141 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A 13-year-old male pseudohermaphrodite (mixed gonadal dysgenesis, unilateral testicular differentiation) was found to be a chromosomal mosaic of the 45, XO/46, XY type, the Y chromosome being a symmetrical dicentric chromosome. Presumed Y chromosomes similar to this one have been observed before, but their identification was not supported by autoradiographic data. In the present study the identification of the dicentric as a Y chromosome was supported by observing a relatively late DNA replication during the S period. The differentiation of testicular tissue on one side may be related to the presence of short arm material of the Y chromosome in the genome of the XY dic cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00297721
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  • 10
    Electronic Resource
    Electronic Resource
    Study of the Suppression of Porphyrin Emission upon Addition of Rare Earth Ions (1999)
    Springer
    Journal of inclusion phenomena and macrocyclic chemistry 35 (1999), S. 271-280 
    Details
    ISSN: 1573-1111
    Keywords: rare earth, porphyrins ; porphyrins ; energy transfer ; luminescence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A topic of constant investigation in recent decades has been the study of electron and/or energy transfer reactions in supramolecular systems. The energy transfer between donor-acceptor depends on the influence of the substituent in the intersystem crossing. The competition between the radiative and non-radiative processes also depends on other factors such as temperature, solvent and energy gap. In this work, we have studied the suppression of the emission of monocarboxyphenyl porphyrins after addition of rare earth ions (RE(III)). The porphyrin emission decreases with the addition of RE(III), no matter which ion is present. When Eu(III) was used, the emission of this ion was not observed either. This suppression happens due to the effect of the heavy atom and not due to the energy transfer through electronic levels between the porphyrin and the RE(III). After the addition of RE(III), the lifetime for MCTPPH2 started to decay biexponentially, indicating the formation of a new species (MCTPPH2-RE(III)) of a shorter lifetime. The presence of NO2 groups in the ortho mesoaryl positions of MCTNPPH2 and the presence of Zn(II) in Zn(MCTPP) decreased both the porphyrin lifetime and emission due to an increase in the spin-orbit coupling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008103216914
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