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  • 1985-1989  (3)
  • 1930-1934
  • Diltiazem  (1)
  • Intensive care patients  (1)
  • Nosocomial infections  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Einfluß einer adjuvanten Immunglobulintherapie auf Infektionen bei Patienten einer operativen Intensiv-Therapie-Station (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 245-256 
    Details
    ISSN: 1432-1440
    Keywords: Immunoglobulin therapy ; Severe infections ; Intensive care patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A randomized controlled clinical trial was conducted on the effects of immunoglobulin in therapy for infections in 104 intensive care patients. At the first sign of infection, one group of 50 patients received an i.v. preparation of immunoglobulin (4×100 ml) combined with antibiotics. The other 54 control patients received antibiotics alone. The most common infections in these patients were pneumonia, septicemia, peritonitis and wound sepsis. Infections were significantly seldom the cause of death, especially in patients with high-risk surgery who had been treated with immunoglobulin (p≤0.05). Likewise ventilation time in the high-risk surgery group averaged only 5.5 days for those receiving immunoglobulin as opposed to 12.7 days in controls (p≤0.01). Whereas the control group, in particular patients with pneumonia, remained in intensive care an average of 21.5 days, those receiving immunoglobulin stayed only 14.8 days (p≤0.01). In general, patients treated with immunoglobulin recovered more rapidly from infections than did controls (p≤0.01).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01711930
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Die Beeinflussung der Organperfusion durch Kalziumblocker und Converting-Enzyminhibitor an der herzinsuffizienten, wachen Ratte (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 262-267 
    Details
    ISSN: 1432-1440
    Keywords: Captopril ; Diltiazem ; Regional blood flow ; Experimental heart failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study examined the regional vascular effects (radioactive microspheres) of converting-enzyme inhibition (captopril, 1mg/kg) and calcium-antagonism (diltiazem, 1 mg/kg) in a rat model of cardiac failure due to large myocardial infarction (n=18, infarct size 40% of the left ventricle) both at rest and during submaximal tread-mill exercise. Diltiazem increased renal, gastrointestinal, coronary and cutaneous blood flow at rest by 29%, 28%, 26% and 37% (p〈0.05 each) and enhanced skeletal muscle blood flow during exercise by 16% (p〈0.05). Captopril improved primarily renal and coronary blood flow at rest (by 59% and 23%, respectively,p〈0.05) and reduced vascular resistance in the gastrointestinal bed by 25% (p〈0.05) without significant effects in other circulatory beds. We conclude that the regional vascular effects elicited by converting-enzyme inhibition and calcium antagonism differ considerably in this animal model of congestive heart failure and may be clinically important. The favourable regional vascular profile of diltiazem deserves further clinical investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01731472
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Influence of architectural design on nosocomial infections in intensive care units—a prospective 2-year analysis (1989)
    Springer
    Intensive care medicine 15 (1989), S. 179-183 
    Details
    ISSN: 1432-1238
    Keywords: Intensive care units ; Nosocomial infections ; Architectural design
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nosocomial infection rates in an old intensive care ward constructed in 1924 were compared with those in a new one constructed in 1986. The nosocomial infection rate in the old unit was 34.2% and that in the new unit 31.9%, with an average of 33%. The most frequent infections were: pneumonia, urinary tract infection, septicaemia and wound infection. After transfer of the intensive care unit (ICU) the incidence and profile of nosocomial infections remained the same. These findings suggest that the influence of architectural design has little impact on the incidence of nosocomial infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01058570
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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