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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 281 (1989), S. 406-410 
    ISSN: 1432-069X
    Keywords: Dermatitis herpetiformis ; Immunoglobulins ; Complement components ; Elution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To better understand the role of autoimmunity in the pathogenesis of dermatitis herpetiformis, linear IgA bullous dermatosis or other skin disorders, the antigenic specificity of the immune reactants bound in vivo in the skin must be identified. In order to do so, one must first be able to elute these immune reactants from the skin. We describe here a simple method of eluting not only specifically bound IgG, but also IgA and other immunoglobulins and complement components from skin biopsy material. The method involves cutaneous washing of the entrapped serum proteins in PBS pH 7 and pH 5 buffers followed by specific immunoglobulin elutions at pH 3 and 2. The IgA deposits which could not be removed by this treatment were eluted by a combination of low pH (0.5 M citrate pH 2) and a chaotropic agent (2 M NaCl). The relative concentration of IgA in eluates when quantitated by fluoroimmunoassay were three-to five-fold higher in dermatitis herpetiformis skin biopsy specimens, than in eluates of bullous pemphigoid or normal skin biopsy specimens.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 26 (1988), S. 1541-1552 
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Positron annihilation lifetime spectroscopy has been used to study the isothermal relaxation response of compression molded bisphenol-A polycarbonate at temperatures of 263, 273, and 303 K. The temperature dependence of both the lifetime and intensity of the ortho-Positronium (o-Ps) pickoff component is discussed in terms of ductile-to-brittle transition behavior and free volume theory. An additive exponential model and the Williams-Watt model were used to analyze the relaxation as a function of temperature and provided results consistent with the anticipated molecular mobility of polycarbonate at sub-Tg temperatures.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 4 (1989), S. 202-204 
    ISSN: 1437-9813
    Keywords: Malignant sacrococcygeal teratoma ; Excision ; Chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between 1954 and 1985, 15 cases of malignant sacrococcygeal teratoma were treated in our institution. Median age at presentation was 20 months (range 9–46 months); there were 14 females and 1 male. Six cases presenting prior to 1970 were treated without chemotherapy with a median survival of 2 months (range 1–7 months). Five patients treated from 1971 to 1979 had tumour excision plus vincristine, actinomycin D, and cyclophosphamide (VAC). Three received radiotherapy in addition and median survival was 11 months (range 0–31 months). Four patients presenting since 1980 had chemotherapy alone after tumour excision. 1 receiving VAC and adriamycin and the remaining patients cisplatinum, bleomycin, and VP16. All these are alive and disease free (median follow-up 27 months; range 15–96 months). It is concluded that initial surgery aimed at complete excision followed by aggressive chemotherapy gives good results.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Reactions of (η2-Ethene)bis(triphenylphosphane)platinum(0) with Dimeric Hexafluorothioacetone. Preparation and Structure of Platina Cyclopentane and Cyclopropane DerivativesThe five-membered (CS)2Pt ring 1 was obtained by the reaction of 2, 2, 4, 4-tetrakis(trifluoromethyl)-1,3-dithietane and (η2-ethene)bis(triphenylphosphane)platinum(0) at low temperatures. 1 is converted at its melting point to the three-membered CSPt ring derivative 2, with elimination of one molecule of hexafluorothioacetone. 2 is also formed directly when the reaction is conducted at temperatures above +30°C. 2 was characterized by an X-ray Structural analysis.
    Notes: Der fünfgliedrige (CS)2Pt-Cyclus 1 kann aus 2, 2, 4, 4-Tetrakis(trifluormethyl)-1,3-dithietan und (η2-Ethen)bis(triphenylphosphan)-platin(0) bei tiefer Temperatur erhalten werden. 1 wandelt sich an seinem Schmelzpunkt unter Abspaltung eines Moleküls Hexafluorthioaceton in den um zwei Ringglieder reduzierten CSPt-Ring 2 um, der auch auf direktem Wege durch Umsetzen des Dithietans bei Temperaturen oberhalb von +30° zugänglich ist. 2 konnte erstmals durch eine Kristallstrukturbestimmung charakterisiert werden.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 14 (1989), S. 607-610 
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: We present the first results from a new apparatus for high spectral and angular resolution studies of sputtered neutral species. The sputtering experiments employ laser-induced fluorescence and a compact fiber-optic-based detection system to yield state-specific angular distributions for the sputtered atom flux. The angular resolution is of the order of 3° and a 260 MHz residual Doppler shift is estimated for the observed atomic transitions. The angular distribution for ground-state zirconium atoms shows clear deviations from the cosine dependence expected from linear cascade theory when sputtered by 1.5 keV Ar+ ions incident at 60° from the surface normal. The peaking of the distribution in the forward direction suggests that a significant fraction of the atoms is ejected by a direct mechanism.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Electron-stimulated desorption of neutrals from methanol-dosed 6063 aluminum alloy has been monitored by laser ionization at 193 nm wavelength. Primary electron energies were in the range 1-3 keV. Time-of-flight spectra for the neutral desorbate were characterized by a low value of the peak velocity (250 m s-1) and a non-Boltzmann form of the distribution. Neutral desorption was ascribed to the parent methoxy (CH3O) species, based on mass spectrometry of the laser-ionization fragmentation pattern as a function of intensity. Ionic desorption was dominated by H+, which was observed to have kinetic energy peaked at ∼3 eV. Approximate estimates of neutral and ion yields were made, based on ion-optical modeling of apparatus transmission characteristics.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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