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  • 1985-1989  (3)
  • Cyclosporin A  (1)
  • Experimental nervous system tumor  (1)
  • ISFET  (1)
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Material
Years
  • 1985-1989  (3)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Cyclosporin A enhances Streptozocin-induced diabetes in CD-1 mice (1987)
    Springer
    Cellular and molecular life sciences 43 (1987), S. 324-327 
    Details
    ISSN: 1420-9071
    Keywords: Cyclosporin A ; cellular immunity ; Streptozocin ; insulitis ; diabetes mellitus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cyclosporin A (CYA), when administered to CD-1 mice treated with a subdiabetogenic dose of Streptozocin (STZ), exacerbated the STZ-induced insulitis and elevated the plasma glucose levels, parallel to a reduction of the insulin content of the pancreas. The possible mechanisms of CYA-mediated aggravation of STZ-induced diabetes are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01945570
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Radiation therapy of rat brain tumor using misonidazole as hypoxic cell sensitizer (1985)
    Springer
    Journal of cancer research and clinical oncology 109 (1985), S. 188-192 
    Details
    ISSN: 1432-1335
    Keywords: Experimental nervous system tumor ; Radiation therapy ; Misonidazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rat brain tumor was used as a model to evaluate radiation therapy with and without misonidazole. BD-IX rats were implanted intracerebrally with an ethylnitrosourea-induced glioma. Three series of experiments were performed, with radiation given 14 days after inoculation of the glioma clone. In each series, the following radiation doses were given: 500 rads once, 1,000 rads once; and 1,000 rads twice, every time with or without two different doses of misonidazole. Radiation therapy significantly prolonged survival when compared to the longevity of the control group. The dose of 1,000 rads given twice was highly effective and the life-span of tumor-bearing rats increased from 72% to 121%. Misonidazole plus irradiation negated the prolongation of survival, achieved with radiation therapy alone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390355
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Online pH,pCO2 andpO2 monitoring system using two-way cyclic pumping of lactate Ringer as a baseline solution (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 45-50 
    Details
    ISSN: 1741-0444
    Keywords: Blood gas ; ISFET ; Lactate Ringer ; Patient monitoring ; pCO2 ; pH ; pO2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A system for the online, simultaneous and intermittent analysis of blood pH, pCO2 pO2 using two-way cyclic pumping of lactate Ringer as a baseline solution is described. The multi-gas sensor is composed of a pH-ISFET with a temperature sensor, a pH-ISFET-based pCO2 sensor and a Clark-type pO2 sensor, bundled in an epoxy rod, and held in place in a flow cell which is directly connectable to an indwelling cannula. The system is controlled by a microcomputer, which supervises pump operation, temperature-compensation of sensor outputs, one-point calibration using sampled blood analysis, and provides graphical display of monitored results. Results of arterial blood-gas monitoring for mongrel dogs are presented which demonstrate the reliability of the present system over extended periods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442819
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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