ISSN:
1573-1111
Keywords:
Nitrosation reactions
;
α-, β-, γ-cyclodextrin
;
dimethyl-β-cyclodextrin
;
ephedrine
;
nitrosoephedrine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract β-, and γ-cyclodextrin and heptakis-2,6-di-O-methyl-β-cyclodextrin enhance the nitrosation rate of l-ephedrine if the nitrosation assay procedure (NAP test) is applied. During this reaction with β-cyclodextrin a solid inclusion compound of β-cyclodextrin andN-nitrosoephedrine precipitates. Solubilities and stabilities of inclusion compounds of the cyclodextrins with ephedrine and nitrosoephedrine, respectively, explain especially the catalytic effects of some cyclodextrins on ephedrine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00663002
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