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Digitale Medien

Histamine nasal provocation test (1989)

HEYNING, P. H. ; HAESENDONCK, J. ; CRETEN, W. ; [weitere]

Oxford, UK : Blackwell Publishing Ltd

Allergy 44 (1989), S. 0

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ISSN: 1398-9995

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: This study is a methodological approach to histamine nasal provocation. The test uses active anterior rhinomanometry and a histamine titration method, challenging both nasal cavities with a metered dose pump. It has been confirmed that the histamine nasal provocation test can differentiate between controls and non-allergic rhinitis patients. This study shows, moreover, that the method is more sensitive in assessing response to histamine provocation when a 25% increase of post-saline nasal airway resistance (PD25) is considered than a PD50 or PD100 criterion. The histamine response, was found to be independent of the baseline nasal airway resistance value. Pronounced unilateral responsiveness was frequently noticed. Both nasal cavities should be challenged and the most reactive side considered.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1398-9995.1989.tb04187.x

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Digitale Medien

The use of fluoroquinolones in chronic otitis suppurativa (1987)

Heyning, P. H. ; Pattyn, S. R. ; Valcke, H. D. ; [weitere]

Springer

Pharmacy world & science 9 (1987), S. S87

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ISSN: 1573-739X

Schlagwort(e): Ciprofloxacin ; Enoxacin ; Mastoiditis ; Otitis media

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie

Notizen: Abstract The present review covers fluoroquinolone usage in chronic otitis suppurativa (COS) in case of chronic otitis media, cholesteatoma, radical mastoid cavity infection and chronic or relapsing otitis externa. A total of six publications were included in the final evaluation. Enoxacin was effective in 35%; ciprofloxacin (five publications) was used in 82 patients with 67% effectivity in otitis externa and otitis media and 61% effectivity in radical mastoid cavity infection. No serious adverse reactions were reported. The promising efficacy of otitis media and otitis extern and safety profile needs further confirmation in double blind prospective clinical studies, that will provide a firm basis for changing the current treatment schedules of COS.