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  • 1
    Digitale Medien
    Digitale Medien
    A gap in surface therapy: topical antihistamines (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 21 (1991), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Allergic and non-allergic rhinitis have been treated by many drugs with different modes of action such as topical disodium cromoglycate and ipratropium bromide, systemic antihistamines and corticosteroid drugs and topical corticosteroids. Yet, these therapies are not entirely satisfactory for all symptoms. The rationale for the topical, intranasal use of antihistamines in patients is discussed. Topical antihistamine agents arc administered in order to avoid the side effects of systematically applied medications, and to reach higher local drug concentrations. H1 receptors of the nasal mucosa play an important role in the physiopathology of allergic and non-allergic rhinitis and even of infectious rhinitis. Most studies using topical antihistamines in rhinitis, had an experimental physiopathological aim and did not explore clinical efficacy. Recently, topical application of levocabastine—a potent H1 antagonist—yielded good clinical results in allergic conjunctivitis, seasonal allergic rhinoconjunctivitis, and non allergic perennial rhinitis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1991.tb01754.x
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  • 2
    Digitale Medien
    Digitale Medien
    Nitrogen oxide (NO and N2O) formation for coal combustion in a fluidized bed: effect of carbon conversion and bed temperature (1993)
    s.l. : American Chemical Society
    Energy & fuels 7 (1993), S. 796-802 
    Details
    ISSN: 1520-5029
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Energietechnik , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ef00042a015
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  • 3
    Digitale Medien
    Digitale Medien
    Histamine nasal provocation test (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 44 (1989), S. 0 
    Details
    ISSN: 1398-9995
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: This study is a methodological approach to histamine nasal provocation. The test uses active anterior rhinomanometry and a histamine titration method, challenging both nasal cavities with a metered dose pump. It has been confirmed that the histamine nasal provocation test can differentiate between controls and non-allergic rhinitis patients. This study shows, moreover, that the method is more sensitive in assessing response to histamine provocation when a 25% increase of post-saline nasal airway resistance (PD25) is considered than a PD50 or PD100 criterion. The histamine response, was found to be independent of the baseline nasal airway resistance value. Pronounced unilateral responsiveness was frequently noticed. Both nasal cavities should be challenged and the most reactive side considered.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1398-9995.1989.tb04187.x
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  • 4
    Digitale Medien
    Digitale Medien
    Nuclear moments in the doubly odd ^1^3^2I isotope
    Amsterdam : Elsevier
    Nuclear Physics, Section A 321 (1979), S. 180-188 
    Details
    ISSN: 0375-9474
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(79)90691-2
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  • 5
    Digitale Medien
    Digitale Medien
    Spatial anisotropy of xenon-defect configurations in cubic single crytals
    Amsterdam : Elsevier
    Physics Letters A 88 (1982), S. 303-306 
    Details
    ISSN: 0375-9601
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9601(82)90075-5
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  • 6
    Digitale Medien
    Digitale Medien
    Hyperbilirubinemia: Significance of the ratio between direct-reacting and total bilirubin
    Amsterdam : Elsevier
    Clinica Chimica Acta 17 (1967), S. 73-79 
    Details
    ISSN: 0009-8981
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(67)90098-8
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  • 7
    Digitale Medien
    Digitale Medien
    Experimental and theoretical study of the carrier capture time (1994)
    Springer
    Optical and quantum electronics 26 (1994), S. S667 
    Details
    ISSN: 1572-817X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Elektrotechnik, Elektronik, Nachrichtentechnik , Physik
    Notizen: Abstract We present an experimental and theoretical study of the carrier capture time into a semiconductor quantum well. We observe for the first time the predicted oscillations of the phonon emission induced capture time experimentally and found good agreement with theory. Calculations show that not only does the LO phonon emission induced capture time (ph capture) oscillate as a function of well width, but also the carrier-carrier scattering induced capture time (c-c capture) oscillates by more than an order of magnitude as a function of the active layer design. Recently, it has been shown that the carrier capture time is directly related to the modulation bandwidth in a quantum well laser. As a result, it might be possible to tailor the modulation bandwidth by optimizing the capture efficiency using a proper design of the active layer in a quantum well laser.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00326654
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  • 8
    Digitale Medien
    Digitale Medien
    On-line estimation of the specific growth rate based on viable biomass measurements: experimental validation (1999)
    Springer
    Bioprocess engineering 21 (1999), S. 389-395 
    Details
    ISSN: 0178-515X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract The application of model based control techniques to biotechnological processes is often hampered due to the lack of reliable on-line sensors. This problem can be tackled by the application of software sensors, in which the available hardware measurements are combined with the model equations. The resulting estimates serve as additional measurements useful for process monitoring and control. In this paper, an observer based estimator for the specific growth rate based on on-line viable biomass measurements is studied. Several fed-batch experiments with baker's yeast in a stirred tank bioreactor illustrate the design, tuning, and implementation from a practical point of view. The main contributions of this paper are to illustrate (i) the implementation and validation of the presented algorithm in real-time, (ii) the use of an advanced on-line biomass measurement, and (iii) the design and tuning of the algorithm from a practical point of view. Real-time knowledge of the specific growth rate is important because it yields information on the viability of the cells and it can be used in real-time feedback control algorithms.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004490050692
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  • 9
    Digitale Medien
    Digitale Medien
    Combining yield coefficients and exit-gas analysis for monitoring of the baker's yeast fed-batch fermentation (2000)
    Springer
    Bioprocess engineering 22 (2000), S. 195-200 
    Details
    ISSN: 0178-515X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract Baker's yeast is one of the micro-organisms that is studied most in literature. Therefore, a lot of knowledge on the biochemical pathways and corresponding yield coefficients is available. This knowledge is combined with measurements of oxygen and carbon dioxide in the exit-gas to determine the coefficients appearing in the stoichiometric equations. In this manner, two measurements are sufficient to yield on-line estimates for biomass, glucose, ethanol and the specific growth rate, and information about the (ill-defined) nitrogen source NH q . This is not possible if the yield coefficients are not included in the estimation procedure. A sensitivity analysis illustrates that this estimation scheme is rather insensitive to uncertainties on the yield coefficients.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/PL00009111
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  • 10
    Digitale Medien
    Digitale Medien
    Electrical stimulation of osteogenesis in delayed union of the rabbit fibula (1983)
    Springer
    Archives of orthopaedic and trauma surgery 101 (1983), S. 247-250 
    Details
    ISSN: 1434-3916
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Diese Arbeit beschreibt ein experimentelles Modell mit Kaninchen, wo die Heilung der Fibulaosteotomien wdhrend 48 Tagen mit Hilfe von Silikongummicylindern verzögert wurde. Nachdem die Gummicylinder extrahiert waren, wurde der Heilungsprozeß auf der rechten Seite mit konstantem, transistorregliertem Gleichstrom à 20 Mikro-Ampère stimuliert, welcher den Fibulaenden mit Stahldrahtelektroden zugeführt wurde. Auf der linken Seite, die zur Kontrolle diente, wurden stromlose Elektroden an den Fibulaenden angebracht. Nach 62 Tagen Stimulation wies ein Tier reichlich überbrückender Callus an der Osteotomistelle auf, während die übrigen Tiere in hohem Grade Synostosen zwischen den Fibulaenden and Tibia aufwiesen. Die Anzahl Synostosen war auf der stimulierten Seite größer. Die histologische Analyse zeigte keine Spuren von Neoplasie.
    Notizen: Summary The present paper describes an experimental model where union was delayed in an osteotomy gap of the rabbit fibula by means of a silicone rubber spacer during 48 days. After the silicone spacer had been removed, electrical transistor regulated direct current of 20 microampères delivered through stainless steel electrodes was used to stimulate osteogenesis on the right side during 62 days. On the left side a sham operation inserting stainless steel electrodes without current was performed. In one out of six animals overbridging callus was received on the stimulated side. In the rest of the animals a high frequency of synostoses between the fibular ends and the tibia was found. There was no significant difference in synostosis formation between the right and the left side. No adverse effect of the current could be detected histologically.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00379938
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