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  • 1
    Electronic Resource
    Electronic Resource
    Microcomputer-based pulse code modulation data-processing system for rocket and balloon observations (1982)
    s.l. : American Chemical Society
    Journal of chemical information and modeling 22 (1982), S. 165-171 
    Details
    ISSN: 1520-5142
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ci00035a007
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  • 2
    Electronic Resource
    Electronic Resource
    Primary afferent depolarization in the trigeminal spinal nucleus of cats (1977)
    Springer
    Experimental brain research 29 (1977), S. 45-56 
    Details
    ISSN: 1432-1106
    Keywords: Trigeminal nerve ; Primary afferent fiber ; Trigeminal spinal nucleus ; PAD ; Intra-axonal record
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intra-axonal recordings were made from trigeminal primary afferent fibers in the trigeminal spinal nuclei oralis and caudalis of cats. Primary afferent depolarization (PAD) was evoked in these afferents by stimulation of the trigeminal peripheral sensory branches (the frontal, infraorbital and lingual nerves), the cerebral cortex and the trigeminal spinal nucleus caudalis. The properties of the PAD, including the threshold, latency, receptive field (sensory branches effective for PAD induction) and frequency-following capacity, were studied with the following results: 1. Stimulation of all the peripheral branches tested as well as the cerebral cortex could evoke PAD in the same single fiber. The latency of the PAD evoked by stimulation of the nerve in which the fiber being recorded from was included was generally shorter than that evoked by other branches. The PAD evoked by peripheral nerve stimulation was assumed to be disynaptic in some cases. 2. The peripherally evoked PAD was chiefly attributable to low threshold afferents in the stimulated sensory branches of the trigeminal nerve. 3. The peripherally evoked PAD could follow stimulation at up to 30/sec, though the amplitude was reduced. 4. Stimulation of the nucleus caudalis could evoke PAD with disynaptic latency in the majority of the fibers terminating in the same nucleus, whereas it evoked PAD with mainly polysynaptic latency in the fibers terminating in the nucleus oralis. The results are discussed in relation to the neuronal circuitry responsible for induction of the trigeminal PAD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236874
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  • 3
    Electronic Resource
    Electronic Resource
    Analysis of the circuitry responsible for primary afferent depolarization in the trigeminal spinal nucleus caudalis of cats (1977)
    Springer
    Experimental brain research 29 (1977), S. 405-418 
    Details
    ISSN: 1432-1106
    Keywords: Trigeminal nerve ; PAD ; Trigeminal spinal nucleus caudalis ; Interneuron ; Subnucleus magnocellularis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Depth analysis was performed on the field potential evoked by stimulation of the infraorbital nerve in the trigeminal spinal nucleus caudalis and the subjacent lateral reticular formation of cats. It was shown by dye marking of the recording positions that each subnucleus of the nucleus caudalis (subnucleus marginalis, gelatinosus and magnocellularis) and the reticular formation could be differentiated from one another by the characteristics of the peripherally evoked field potentials. Responses of neurons were extracellularly recorded in the subnuclei gelatinosus and magnocellularis of the nucleus caudalis and in the reticular formation to stimulation of the trigeminal sensory branches (the frontal, infraorbital and lingual nerves), the nucleus ventralis posteromedialis of the thalamus and the cerebral cortex. The properties of the neurons were studied in relation to their thresholds, latencies, receptive fields (sensory branches effective for spike generation) and frequency-following capacities. These responses were then compared with properties of the PAD induced in the fibers terminating in the nucleus caudalis by similar peripheral and central stimulation. It was found that the neurons in the subnucleus magnocellularis were the most likely candidates for the interneurons mediating the peripherally evoked disynaptic PAD in the trigeminal nerve fibers terminating in the nucleus caudalis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236179
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  • 4
    Electronic Resource
    Electronic Resource
    Subependymal giant-cell tumor: Astrocytic or neuronal? (1983)
    Springer
    Acta neuropathologica 60 (1983), S. 271-277 
    Details
    ISSN: 1432-0533
    Keywords: Tuberous sclerosis ; Subependymal giant-cell tumor ; Immunohistochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tissue from seven patients with tuberous sclerosis and subependymal giant-cell tumors was examined with special stains, immunohistochemistry, and electron microscopy. Immunoreactive glial fibrillary acidic protein (GFAP) was not found in the giant cells of four tumors, but was present in some tumor cells in the other three. Immunoreactive S-100 protein was present in tumor cells of six cases; it was also seen in more tumor cells than was GFAP. Electron microscopy was similar in all cases and showed that the tumor cells had numerous organelles — many dense bodies thought to be primary lysosomes, swollen mitochondria, Golgi complexes, rough and smooth endoplasmic reticulum, free ribosomes, and sparsely distributed intermeadiate filaments. In one case, neurosecretory granules, microvilli, and synapses were observed. In another subject, prominent, thick bundles of glial filaments were seen. These findings suggest that the tumor is made up of unique cells in addition to cells with recognizable neuronal or astrocytic features.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691876
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  • 5
    Electronic Resource
    Electronic Resource
    Distribution and ultrastructure of Alzheimer's neurofibrillary tangles in postencephalitic parkinsonism of Economo type (1981)
    Springer
    Acta neuropathologica 55 (1981), S. 59-62 
    Details
    ISSN: 1432-0533
    Keywords: Alzheimer's neurofibrillary tangle ; Postencephalitic parkinsonism ; Twisted tubule ; Straight tubule
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution and ultrastructure of Alzheimer's neurofibrillary tangles (ANT) in the brain stem, hypothalamus, and Ammon's horn were studied in four patients with postencephalitic parkinsonism of Economo type (PEPE). The distribution of ANT was as previously reported; the pattern of distribution resembled to that of amine-containing nerve cells. Ultrastructurally, ANT revealed twisted tubules (TT), but straight tubules (ST) of 150 Å width were also found in the locus ceruleus of three cases; sometimes, TT and ST were mixed in a single neuron. Whether the coexistence of TT and ST in the locus ceruleus is a characteristic ultrastructural feature of ANT in PEPE or a regional peculiarity could not be determined. Ultrastructurally, ANT in PEPE were identical to those found in the brains of patients with Alzheimer's disease or senile dementia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691532
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  • 6
    Electronic Resource
    Electronic Resource
    Peripheral medulloepithelioma (1982)
    Springer
    Acta neuropathologica 57 (1982), S. 137-142 
    Details
    ISSN: 1432-0533
    Keywords: Medulloepithelioma ; Peripheral nerve ; Congenital
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of congenital peripheral medullo-epithelioma arising in the sciatic nerve of a 6-month-old boy is reported. Histologically, areas of primitive neural tumor merged with areas showing differentiation into ependymoma, astrocytoma, oligodendroglioma, and ganglioneuroma. These lines of differentiation were confirmed by electron microscopy and immunohistochemistry. Despite the malignant nature of the tumor, 7 years after amputation of the affected leg, the child is alive without recurrence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00685381
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  • 7
    Electronic Resource
    Electronic Resource
    Spatio-temporal patterns of pre- and postsynaptic inhibition induced by primary afferent activation in the trigeminal sensory nucleus in cats (1980)
    Springer
    Experimental brain research 40 (1980), S. 154-163 
    Details
    ISSN: 1432-1106
    Keywords: Afferent inhibition ; Trigeminal sensory nucleus ; Postsynaptic inhibition ; Presynaptic inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Spatio-temporal patterns of pre- and postsynaptic inhibition were studied in the trigeminal spinal nucleus oralis of cats by means of systematic electrical stimulation of the facial skin. Stimulation of the facial skin induced an EPSP-IPSP sequence in trigemino-thalamic relay cells (TRC). The IPSP was depressed by picrotoxin but was resistant to strychnine. The largest IPSP was evoked from the center of the excitatory area, where stimulation induced the largest EPSP and spike potentials at the lowest intensity in the same TRC. The amplitude of the IPSP decreased with increasing distance from the center in parallel with that of the EPSP. In the great majority of trigeminal primary afferent fibers, the largest primary afferent depolarization (PAD) was not evoked from the center of the excitatory area, where the threshold for spike generation was lowest, but from the adjacent points on the face. Spike activities in a trigeminal primary afferent fiber did not evoke any detectable PAD in itself. The duration of the PAD was definitely longer than the IPSP in TRC. However, the temporal distribution of the peak of PADs was very similar to that of the EPSP in TRC. Inhibition was evoked in glutamate-induced spike discharges of TRC by stimulation of the points on the face, which were located close to the center of the excitatory area of the TRC. However, the afferent inhibition of both spontaneous and peripherally induced spike discharges of TRC outlasted the postsynaptic inhibition. Thus, the late phase of the afferent inhibition is most probably due to presynaptic inhibition. Presynaptic inhibition, together with postsynaptic inhibition, would be involved also in the early phase of afferent inhibition through its mutual inhibitory organization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237533
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  • 8
    Electronic Resource
    Electronic Resource
    Identification and input-output properties of bulbar reticular neurons involved in the cerebral cortical control of trigeminal motoneurons in cats (1983)
    Springer
    Experimental brain research 49 (1983), S. 363-372 
    Details
    ISSN: 1432-1106
    Keywords: Orbital gyrus ; Trigeminal motoneuron ; Bulbar reticular formation ; Excitatory neuron ; Inhibitory neuron
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurons found in the medial bulbar reticular formation were activated by stimulation of the orbital gyms and responded with antidromic spike potentials to selective stimulation of either the masseter or anterior digastric motoneuron pool in the trigeminal motor nucleus in cats anesthetized with α-chloralose. These two kinds of reticular neurons were assumed to be inhibitory neurons projecting to masseter motoneurons (IM neurons) and excitatory neurons projecting to anterior digastric motoneurons (ED neurons), involved in the effects of stimulation of the orbital gyrus on trigeminal motoneurons: inhibition of masseter motoneurons and excitation of anterior digastric motoneurons. Input-output properties of IM and ED neurons were studied intracellularly with the following results: (1) stimulation of the orbital gyrus evoked EPSPs in im and ED neurons with mono- and polysynaptic latencies; and (2) stimulation of the lingual nerve evoked a spike potential in a few IM and ED neurons after a rather long latency, indicating that the pathways involved in the cortical control of trigeminal motoneurons via IM and ED neurons were basically separate from those responsible for the reflex control by the peripheral inputs Intracellular injection of horseradish peroxidase revealed that both IM and ED neurons were small or medium in size and the former were smaller than the latter, while none of the large reticular neurons directly projected to the trigeminal motor nucleus. This suggests a possible functional differentiation among bulbar reticular neurons according to cell size.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238778
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  • 9
    Electronic Resource
    Electronic Resource
    Untersuchungen von sekundären Elektrokapillar-Effekten. II. Die Elektrokapillarerscheinungen an dünnen Flüssigkeitsfilmen (1979)
    Springer
    Colloid & polymer science 257 (1979), S. 783-783 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01474114
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  • 10
    Electronic Resource
    Electronic Resource
    Elektrotransport in geschmolzenen K/Tl-Legierungen (1980)
    Springer
    Colloid & polymer science 258 (1980), S. 792-792 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01384380
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