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  • 1980-1984  (1)
  • 1975-1979  (1)
  • Chemical Engineering  (1)
  • Guinea pig epidermis  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 269 (1980), S. 153-159 
    ISSN: 1432-069X
    Keywords: Serine-specific isoaccepting tRNAs ; Guinea pig epidermis ; Keratinization ; Triamcinolon ; Serinspezifische isoakzeptierende tRNA ; Meerschweinchenepidermis ; Keratinisation ; Triamcinolon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Durch „reversed phase”-Chromatographie von 3H- oder 14C-serinbeladenen Gesamt-tRNA-Präparaten wurde das Multiplizitätsmuster der serinspezifischen Transfer-Ribonucleinsäuren in der Meerschweinchenepidermis ermittelt und mit dem der Leber als Bezugssystem verglichen. Fünf tRNAser (I–V) konnten dargestellt werden, von denen zwei, tRNA I ser und tRNA V ser , „typisch” für die Epidermis zu sein scheinen und insofern möglicherweise Stoffwechselbesonderheiten der epidermalen Zelldifferenzierung reflektieren. Diese Hypothese wurde weiter untermauert, indem gezeigt werden konnte, daß lokale Applikation des Corticosteroids Triamcinolon in der Meerschweinchenepidermis selektiv tRNA I ser und tRNA V ser auf das Zwei- bis Dreifache erhöht. Die mögliche Bedeutung dieser Befunde wurde eingehend diskutiert.
    Notes: Summary The pattern of serine-specific tRNAs from guinea pig epidermis was determined and compared to that from liver by employing reversed phase chromatography on total tRNA preparations aminoacylated with 3H- or 14C-serine. Five tRNA s ser (I–V) were found, two of which, tRNA I ser and tRNA V ser , appear to be “typical” for epidermis and in so far probably reflect in some way metabolic pecularities of epidermal cell differentiation. This hypothesis was further corroborated by showing that the locally applied corticosteroid triamcinolon selectively increases tRNA I ser and tRNA V ser 2-3-fold. The implications of these findings were discussed in detail.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The high strength to weight ratio of glass reinforced plastics (FRF) combined with their fabrication flexibility has led to increasing use in new applications that no other materials could satisfy. FRF often replaces metals in traditional applications. Increasingly stringent flammability requirements have led to the use of alumina trihydrate filler, usually in combination with halogenated rosins. However, difficulties in compounding and fabrication often limit, the alumina trihydrate loading. This requires substantial increments of halogenated resin to meet specific flammability restrictions. In such composites, the price of the compound may be too high for a given application and one must often compromise substantially on both processing and physical property performance. Alumina trihydrate filled systems commonly suffer from poor glass fiber wet out and mold flow, with reduced strength and uniformity in fabricated parts. This paper describes how a unique silane pretreatment for alumina trihydrate permits bulk molding compound (BMC)/sheet molding compound (SMC) formulations to be developed with increased loadings of the filler, reduced filler wet out time, and improvements in glass dispersion, mold flow out, strength and uniformity of the composite. The paper also shows how the halogenated resin content of flame retarded systems may be minimized by the use of this silane treated alumina trihydrate.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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