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  • 1
    Electronic Resource
    Electronic Resource
    Apparent discrepancy between the insulin secretory responses in vivo and in vitro in carbohydrate-intolerant sand rats (1979)
    Springer
    Diabetologia 17 (1979), S. 367-369 
    Details
    ISSN: 1432-0428
    Keywords: Sand rat ; insulin secretion ; glucose loading ; isolated islet ; insulin content
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A subpopulation (n=27) of normoglycaemic Sand rats was characterized as carbohydrateintolerant by intraperitoneal glucose loading. Five of these animals did not show any rise in peripheral insulin concentrations when injected with glucose. However, when isolated by collagenase digestion their islets still exhibited a significant enhancement of insulin secretion in response to glucose, glyceraldehyde, mannose and theophylline. The in vitro secretory responses were comparable to those of islets from carbohydrate-tolerant Sand rats. The results underline the importance of the natural environment for the B-cell response in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01236271
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Estimation of pancreatic IRI output rate and its relation to glucose tolerance in normal anaesthetized dogs (1975)
    Springer
    Diabetologia 11 (1975), S. 291-299 
    Details
    ISSN: 1432-0428
    Keywords: Insulin secretion rate ; pancreatic blood flow ; mathematic model ; IRI concentration ; blood glucose ; glucose assimilation ; dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pancreaticoduodenal and portal venous blood flows were recorded electromagnetically in anaesthetized dogs. Blood glucose and IRI were measured in the arterial, portal, and peripheral venous as well as in the intestinal venous blood. By a mathematical model the actual net IRI output of the whole pancreas was estimated. Under basal conditions it is 10.2±2.4 mU/min (n = 30; 26 kg mean body wt). After i.v. glucose injection, IRI output is rapidly enhanced. The biphasic nature of this reaction was unequivocally demonstrated by consideration of the ratio IRI output: blood glucose. Pancreaticoduodenal blood flow increases transiently in relation to the increased blood glucose concentration. The IRI secretion rate is well correlated with the blood glucose concentration and to the amounts of glucose or of blood reaching the whole pancreas. It is also correlated with the portal IRI concentration. The overall peripheral venous or arterial IRI concentrations are correlated with the IRI secretion rate, but not in all individual experiments. The different phases of IRI output (basal rate, stimulated output 1–10 min and 10–60 min) show no influence on each other, nor are they correlated with the peripheral IRI concentration area. Basal IRI output is negatively correlated with the glucose assimilation constants. These constants or the peripheral B G areas, however, are independent of the stimulated IRI output rate. However, both the assimilation constants and the peripheral BG areas are related to the peripheral IRI concentration areas. Hepatic uptake of insulin and dynamics of pancreatic blood flow seem to contribute considerably to the estimated correlation pattern.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422394
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Purification of the four lysine-specific transfer ribonucleic acids from chick embryos
    Amsterdam : Elsevier
    BBA Section Nucleic Acids And Protein Synthesis 331 (1973), S. 221-230 
    Details
    ISSN: 0005-2787
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2787(73)90435-8
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  • 4
    Electronic Resource
    Electronic Resource
    Ultraviolett-inaktivierung der phenylalanin- und lysinspezifischen Transfer-Ribonucleinsauren
    Amsterdam : Elsevier
    BBA Section Nucleic Acids And Protein Synthesis 103 (1965), S. 418-430 
    Details
    ISSN: 0005-2787
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2787(65)90135-8
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Analysis of dynamic pattern formation in nonlinear Fabry-Perot resonators (1994)
    Springer
    Applied physics 59 (1994), S. 581-589 
    Details
    ISSN: 1432-0649
    Keywords: 61.30.-v ; 42.50.Lc ; 42.65.Jx ; 42.65.Pc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present a detailed analysis of transverse effects and pattern formation in bistable optical elements. The system we investigate consists of a Fabry-Perot resonator for the optical feedback element with a nematic liquid-crystal cell used as an optically nonlinear intracavity medium. On illumination with a cw-laser beam, the system causes the beam to break up into several individual spots, passing through several transitions before finally reaching a stationary state. We devise a theoretical model which is used as the basis for numerical simulations of the system. The simulation results are in good agreement with experiment. Finally, we characterize the principal instability of the system using a linear stability analysis of the theoretical model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01081177
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  • 6
    Electronic Resource
    Electronic Resource
    Changes in the serine-specific transfer ribonucleic acid pattern of guinea pig epidermis after corticosteroid treatment (1980)
    Springer
    Archives of dermatological research 269 (1980), S. 153-159 
    Details
    ISSN: 1432-069X
    Keywords: Serine-specific isoaccepting tRNAs ; Guinea pig epidermis ; Keratinization ; Triamcinolon ; Serinspezifische isoakzeptierende tRNA ; Meerschweinchenepidermis ; Keratinisation ; Triamcinolon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Durch „reversed phase”-Chromatographie von 3H- oder 14C-serinbeladenen Gesamt-tRNA-Präparaten wurde das Multiplizitätsmuster der serinspezifischen Transfer-Ribonucleinsäuren in der Meerschweinchenepidermis ermittelt und mit dem der Leber als Bezugssystem verglichen. Fünf tRNAser (I–V) konnten dargestellt werden, von denen zwei, tRNA I ser und tRNA V ser , „typisch” für die Epidermis zu sein scheinen und insofern möglicherweise Stoffwechselbesonderheiten der epidermalen Zelldifferenzierung reflektieren. Diese Hypothese wurde weiter untermauert, indem gezeigt werden konnte, daß lokale Applikation des Corticosteroids Triamcinolon in der Meerschweinchenepidermis selektiv tRNA I ser und tRNA V ser auf das Zwei- bis Dreifache erhöht. Die mögliche Bedeutung dieser Befunde wurde eingehend diskutiert.
    Notes: Summary The pattern of serine-specific tRNAs from guinea pig epidermis was determined and compared to that from liver by employing reversed phase chromatography on total tRNA preparations aminoacylated with 3H- or 14C-serine. Five tRNA s ser (I–V) were found, two of which, tRNA I ser and tRNA V ser , appear to be “typical” for epidermis and in so far probably reflect in some way metabolic pecularities of epidermal cell differentiation. This hypothesis was further corroborated by showing that the locally applied corticosteroid triamcinolon selectively increases tRNA I ser and tRNA V ser 2-3-fold. The implications of these findings were discussed in detail.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00406535
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    Paper (German National Licenses)
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