ISSN:
1432-0428
Keywords:
Epidemiology
;
early onset diabetes mellitus
;
incidence
;
secular trend
;
seasonally
;
geographical distribution
;
symptom duration
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary This study presents the clinical-epidemiological analysis of data from 769 individuals, representing 〉 95% of all cases of diabetes mellitus diagnosed during the first 20 years of life among the Danish male birth cohorts 1949–1956 inclusive. It is concluded that except for a very few, all cases of diabetes developing during the first 20 years of life are insulin-dependent with a duration of symptoms 〈 2 months before diagnosis in 〉 75% of the cases. The cases were evenly distributed within Denmark at the time of birth as well as of diagnosis, and 〉 98% were admitted to hospital at diagnosis. A relatively higher proportion of cases diagnosed during autumn and winter periods was found, but was not statistically significant. Incidence was analysed in a regression model with age and calendar time as variables; the variation of age at onset was similar to previous studies with a peak at pre-school age and at puberty. Contrary to previous Danish analyses, we found a significant calendar time variation with steadily increasing age-specific incidences from the beginning of 1950s until an apparent maximum in mid-1970s.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00279933
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