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  • 1980-1984  (3)
  • CT  (1)
  • Erythrocyte superoxide dismutase  (1)
  • Free testosterone  (1)
  • Amylase assay
  • 1
    Electronic Resource
    Electronic Resource
    The changes in the binding capacity of testosterone-oestradiol binding globulin (TeBG) following castration and DES-D administration in patients with prostatic carcinoma (1982)
    Springer
    Urological research 10 (1982), S. 119-122 
    Details
    ISSN: 1434-0879
    Keywords: TeBG ; Free testosterone ; Acid phosphatase ; Prostatic carcinoma ; Castration and DES-D therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The levels of plasma testosterone, testosterone-oestradiol binding globulin (TeBG) and total serum acid phosphatase (TSAP) following antiandrogenic hormone therapy were investigated in 17 patients with prostatic carcinoma. The low levels of plasma total and free testosterone induced by castration decreased further after diethylsitlboestrol diphosphate (DES-D) administration. Plasma TeBG binding capacity after castration was 118.9% of the pre-treatment level and increased to 193.9%, 204.0% and 212.7% at 1, 2 and 3 weeks after DES-D dosing. The in vitro binding of 3H-testosterone to TeBG was not influenced in the presence of DES-D or stilboestrol. Clinical response following the DES-D therapy was associated with a decrease in the levels of TSAP. A significantly inversed correlation was found between the decrease in TSAP and increase in TeBG at completion of DES-D therapy. These results suggest that the high binding capacity of TeBG lowers the biologically active fraction of testosterone and thus may produce clinical effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255953
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in erythrocyte superoxide dismutase in a patient with copper deficiency (1980)
    Springer
    European journal of pediatrics 134 (1980), S. 121-124 
    Details
    ISSN: 1432-1076
    Keywords: Copper deficiency ; Erythrocyte superoxide dismutase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a patient with typical copper deficiency, we found superoxide dismutase (SOD, 1.15.1.1) activity and copper in erythrocytes to be decreased to 52% and 46% of age-matched controls, respectively. However, these were not so markedly depleted as plasma copper (17%) or ceruloplasmin (20%). After copper replacement therapy, erythrocyte copper and SOD activity gradually returned to the control levels. Although certain abnormalities reported in copper deficiency in animals were expected, osmotic fragility of erythrocytes of the patient was normal and damage of the liver and heart were not a feature as far as could be determined by electrocardiography and routine laboratory examinations. Probably a decrease of SOD to this extent is not severe enough to lead to superoxide-induced damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01846029
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Pituitary abnormalities detected by high resolution computed tomography with thin slices in primary hypothyroidism and Turner syndrome (1984)
    Springer
    European journal of pediatrics 142 (1984), S. 25-28 
    Details
    ISSN: 1432-1076
    Keywords: Hypothyroidism ; Turner syndrome ; CT ; Pituitary abnormality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pituitary hyperplasia, microadenoma or an empty sella was detected in three children with primary hypothyroidism and three with Turner syndrome with the use of high resolution contrast-enhanced computed tomography (CT) with thin slices. Hyperplasia or microadenoma of the pituitary gland frequently occurs secondary to primary hypothyroidism and gonadal dysgenesis, and recognition of these results may eliminate unnecessary surgery in favor of hormone replacement therapy. High resolution contrast-enhanced CT, especially coronal CT, with thin slices is very helpful in demonstrating these pituitary abnormalities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442585
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    Paper (German National Licenses)
    Fulltext
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