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  • 1
    Electronic Resource
    Electronic Resource
    Some ultrastructural effects of testosterone and insulin on the ventral prostate of rats in organ culture (1977)
    Springer
    Cell & tissue research 181 (1977), S. 327-337 
    Details
    ISSN: 1432-0878
    Keywords: Prostate ; Tissue culture ; Testosterone ; Insulin ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The fine structure of the secretory epithelial cells of rat's ventral prostate has been studied following organ culture. Culturing with either testosterone or insulin alone, and with the two hormones combined, were carried out to investigate how insulin modifies the action of testosterone on the maintenance of cellular integrity. After 4 days in hormone-free culture, the secretory epithelial cells showed signs of cellular atrophy and regression, involving loss of the apical microvilli, absence of the apical secretory vacuoles, atrophy of the Golgi apparatus, decrease in rough endoplasmic reticulum and the appearance of autophagic vacuoles. The presence in the medium of either testosterone or insulin alone, or combined, prevented cellular atrophy and regression. The best maintenance of cellular integrity was obtained in a culture containing both hormones. The effects of insulin was approximately equivalent to those of testosterone in the maintenance of cellular integrity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223108
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Light and electron microscopy of the ducts and their subepithelial tissue in the rat ventral prostate (1978)
    Springer
    Cell & tissue research 192 (1978), S. 381-390 
    Details
    ISSN: 1432-0878
    Keywords: Prostatic duct ; Epithelium ; Basal cell ; Muscular coat ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ducts of the rat ventral prostate have been studied by light and electron microscopy for elucidation of their role in prostatic function. The epithelium of the main duct consists of simple columnar cells and polymorphic basal cells. The columnar cells show no indication of secretory activity. The basal cells contain bundles of filaments of 5–6 nm thickness and numerous pinocytotic vesicles. The ducts are surrounded by layers of circular smooth muscle cells interspersed with nerve axons. On ultrastructural grounds the ducts do not appear to secrete material into the seminal fluid, but apparently the muscular coat actively helps drain the gland during ejaculation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00212320
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The fine structure of ventral prostatic secretory epithelial cells in older rats (1979)
    Springer
    Cell & tissue research 203 (1979), S. 181-188 
    Details
    ISSN: 1432-0878
    Keywords: Ventral prostate ; Epithelial cells ; Electron microscopy ; Light microscopy ; Older rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ventral prostatic secretory epithelial cells in older rats were studied by light and electron microscopy. The cells vary in height in different parts of the same organ, and ultrastructurally they show the presence of a developed secretory apparatus such as well-developed Golgi body and abundant rough endoplasmic reticulum. They also show signs of a depressed secretory activity, involving occasional emiocytosis of apical secretory vacuoles and a paucity of condensing vacuoles in the Golgi region and above it. Further, they are characterized by the frequent occurrence of supra and paranuclear pleomorphic lysosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237232
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Cholesterol changes in developing testicular interstitial cells of the mouse: Histochemical and biochemical study (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 163 (1969), S. 595-601 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In combination with biochemical determination of cholesterol in testes, cholesterol was studied histochemically in the testicular interstitial cells of dd strain mice from 5 to 63 days.Cholesterol is found in interstitial cells at five days and cholesterol positive interstitial cells increase significantly from 7% at 5 days to 47% at 21 days (17% at 7 days, 21% at 10 days and 31% at 14 days) and thereafter gradually to 58% at 63 days (50% at 28 days, 54% at 35 days, 56% at 42 days, 58% at 49 days and 57% at 56 days).The cholesterol concentration of testes (μg of cholesterol per mg testicular weight) remains at low values before 42 days (1.33 at 5 days, 2.12 at 7 days, 1.89 at 10 days, 2.18 at 14 days, 2.16 at 21 days, 1.63 at 28 days and 2.09 at 35 days) but it increases rapidly at days 42-49 (2.21 at 42 days and 5.16 at 49 days) and then it is almost unchanged (5.47 at 56 days and 5.18 at 63 days).From these results it is suggested that (1) at five days testicular steroid could be elaborated and (2) the capacity of interstitial cells to produce testicular steroid elevates actively from 42 to 49 days.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091630411
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    Paper (German National Licenses)
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