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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 79 (1975), S. 2674-2687 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 8 (1978), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The frequency of HLA antigens in twenty-two Caucasian patients with allergic broncho-pulmonary aspergillosis (ABPA) and sixty-nine unrelated Caucasian controls was determined. The results indicated that there was no increased frequency of a specific HLA antigen in patients with ABPA. Moreover, studies in thirteen families of ABPA patients also demonstrated that, within families, there was no consistent association between a specific haplotype and asthma, allergies or hay fever.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 9 (1979), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The availability of inhaled beclomethasone diproprionate permitted the discontinuation of continuous, long-term systemic corticosteroid therapy (SCT) in a group of asthmatics who had previously required SCT to control their asthma. Twelve patients had been on SCT for a period of 2–22 years with an average duration of 7 years. To determine whether this previous long-term SCT and the current use of inhaled beclomethasone diproprionate had an effect on leucocyte functions, a variety of studies reflecting T lymphocyte, B lymphocyte and granulocyte function was done. The results were compared with those of twelve asthmatic patients of similar age ranges who had never received steroids. Results showed that the two patient populations could not be differentiated on the basis of phytohaemagglutinin stimulation of lymphocytes, sheep erythrocyte rosette formation, IgG, IgA, IgM and IgE concentrations or granulocyte bactericidal activity. Delayed skin reactivity was present in both groups, with more positive reactions in the non-SCT group. Polymorphonuclear adherence values were slightly lower in the SCT female population using beclomethasone diproprionate. The latter two minor differences may be due to the previous SCT, the use of beclomethasone diproprionate or the limited population of patients studied. We conclude from these studies that the long-term use of SCT at the low doses required for control of asthma resulted in little permanent effect on the variety of lymphocyte and granulocyte functions tested.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 8 (1978), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The clinical course of twenty-one patients who presented with life-threatening symptoms, appearing to be allergic in aetiology, is described. In ten of these patients, clinical evaluation established a diagnosis, for example: drug allergy, food allergy, a curious form of hospital addiction syndrome, an underlying malignancy, systemic mast cell disease or a complement abnormality. In the remaining subjects, it was found that their condition could be stabilized with sympathomimetics, antihistamines and corticosteroids. In those in whom no aetiology could be found, there was usually a spontaneous subsidence of the frequency and severity of attacks or spontaneous remission. No fatalities occurred.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 253 (1975), S. 36-37 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Some sort of soap-polymer interaction does occur (Fig.l); at all polymer concentrations the drag reduction is significantly improved in the surfactant solution. The turbulent flow line of SDS alone was not measurably different from that of pure water. This seems to be the first evidence that the ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 42 (1978), S. 105-113 
    ISSN: 1432-0533
    Keywords: Remyelination ; X-Irradiation ; Oligodendrocytes ; Multiple sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rat and cat spinal cords were exposed to 2000, 3000 or 4000 rads of x-irradiation prior to producing an area of primary demyelination in the dorsal columns by the injection of lysolecithin. In animals irradiated with 4000 rads no remyelination by either Schwann cells or oligodendrocytes occurred. With 2000 rads both types of remyelination occurred, but when compared to unirradiated controls, central remyelination was less extensive, while Schwann cells remyelinated a greater percentage of axons. With 3000 rads the results were variable, some animals responded similarly to those in the 4000 rad group, whereas others responded as the 2000 rad animals. Oligodendrocytes were found among the persistently demyelinated axons in the 4000 rad animals and their processes were associated with, but only rarely formed a myelin sheath round, the demyelinated axons. It was concluded that irradiation damage to local cells was responsible for the inhibition of remyelination but it could not be determined if this was due to its effect on the oligodendrocytes alone. The origin of the oligodendrocytes found among the demyelinated axons is discussed in this context.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurocytology 4 (1975), S. 573-585 
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Myelination was inhibited in the spinal cord of three day-old rats with 2000 rads of X-irradiation. Myelination subsequently occurred as a result of caudal migration of oligodendrocytes and extensive invasion of the cord by Schwann cells. Although oligodendrocytes were present in areas containing Schwann cells, astrocytes were absent. The presence of Schwann cells in the neuropil of the spinal cord did not stimulate production of basement membrane by astrocytes, so no new glial limiting membrane was formed. Evidence is presented which suggests that if astrocytes do not form a glial limiting membrane when opposed by large numbers of Schwann cells they are destroyed by the invading cells. It is suggested that the glial limiting membrane normally inhibits entry of Schwann cells into the central nervous system; if this is destroyed and not reconstituted, Schwann cells can migrate freely into the neuropil.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 16 (1978), S. 531-536 
    ISSN: 1741-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Le but de cette étude est de déterminer la sensibilité de l'impédance électrique de la cage thoracique aux changements du volume sanguin dans différentes régions du thorax. Pour cela, le sang de chiens récemment sacrifiés a été infusé de manière variable à la fois par étapes et en continu dans les ventricules, oreillettes, poumons et également dans des segments isolés de l'aorte. Les résultats montrent que les sensibilités de l'impédance aux changements de volume dans les oreillettes et l'aorte sont similaires, tandis que les changements de volume dans les ventricules sont nettement moins d'effet. Des pulsations de sang de volume égal dans les poumons ou l'aorte donnent un changement d'impédance d'amplitude similaire, mais une estimation basée sur les changements de pression de contrôle indique que l'effet des changements de volume sanguin dans l'aorte modifie l'impédance de moins de 30%. Ces données montrent donc que des changements de volume de plusieurs des structures cardiovasculaires intrathrocaques participent probablement à la création d'un changement d'impédance électrique cardiaque composite.
    Abstract: Zusammenfassung Der Zweck dieser Studie war, die Sensibilität der brustkorbbezüglichen elektrischen Impedanzveränderung auf Blutvolumenveränderungen in verschiedenen Regionen des Brustkorbs zu bestimmen. Bei kurz zuvor euthanasierten Hunden wurde Blut sowohl schrittweise als auch in kontinuierlicher Form abwechselnd in die Hirnkammern, Atria, Lungen und isolierte Segmente der Aorta infusiert. Die Resultate zeigen, daß die Impedanzsensibilität in bezug auf die Volumenveränderungen in Atria und Aorta in beiden ähnlich ist, während die Volumensveränderungen der Hirnkammern eine bedeutend kleinere Wirkung zeigten. Gleiche Blutvolumenimpulse in Lunge oder Aorta erzeugen eine ähnlich große Impedanzveränderung, jedoch weisen auf Regeldruckveränderungen basierende Schätzungen darauf hin, daß die Wirkung der Aorta-Volumenveränderung auf die Impedanz kleiner als 30% ist. Deshalb sind die Daten eine Indikation dafür, daß Volumenveränderungen verschiedener intrathorakischer herzgefäßbezüglicher Strukturen möglicherweise zur Erzeugung einer zusammengesetzten kardiogenen elektrischen Impedanzveränderung beitragen.
    Notes: Abstract The purpose of this study was to determine the sensitivity of the thoracic electrical impedance change to blood-volume changes in various regions of the thorax. Using recently euthanatised dogs blood was infused in both a stepwise and a continuously varying manner into the ventricles, atria, lungs and isolated segments of the aorta. The results show that the impedance sensitivities to volume changes in the atria and aorta are similar, whereas the volume changes of the ventricles showed a significantly smaller effect. Equal blood-volume pulses into the lungs or aorta cause an impedance change of a similar magnitude, but estimates based on control-pressure changes indicate the effect of aorta volume change on the impedance to be less than 30%. The data, therefore, indicate that changes in volume of several of the intrathoracic cardiovascular structures are likely to be involved in the generation of a composite cardiogenic electrical impedance change.
    Type of Medium: Electronic Resource
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