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  • 1970-1974  (3)
  • 1960-1964
  • Rats  (2)
  • Alpha-Methyl-Para-Tyrosine  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 28 (1973), S. 171-183 
    ISSN: 1432-2072
    Schlagwort(e): Ethanol Drinking ; Ethanol Reinforcement ; Fixed-Ratio Size ; Food Deprivation ; Rats
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Rats having prior experience with ethanol drinking were subjected to geometrically increasing fixed-ratio (FR) schedules of ethanol reinforcement (8% W/V). The rats were tested first food deprived and then food satiated. Each third day ethanol was the reinforcer (0.25 ml/reinforcement), while on other days water, which served as the vehicle control, was available. Food satiating the rats decreased responding for ethanol whereas responding for water was not changed. Under both food conditions ethanol maintained responding at FR's up to 256 with response totals exceeding water control values. As the FR size increased to intermediate values, the number of ethanol responses increased. Further FR increases resulted in decreases in ethanol responding. The pattern of FR responding was similar to that maintained by other reinforcers. Maximum ethanol responding occurred at the beginning of the 6-h sessions, followed by a pause and then intermittent bursts of responding. Water responding was not characterized by a specific pattern. It was inferred that the odor of ethanol functioned as a discriminative stimulus, and it was concluded that ethanol served as a reinforcer for the rat.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-2072
    Schlagwort(e): Lysergic Acid Diethylamide ; Para-Chlorophenylalanine ; Alpha-Methyl-Para-Tyrosine ; Operant Conditioning
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The bar-pressing behavior of hungry rats was maintained by a fixed-ratio schedule of food reinforcement. At 5 and 12 days after pretreatment with p-chlorophenylalanine (PCPA), a subtreshold dose (20 μg/kg) of lysergic acid diethylamide (LSD) was found to disrupt this behavior. No such disruption occurred when PCPA pretreatment was followed by either a distracting external stimulus (tone) or a low dose of D-amphetamine (0.3 mg/kg). Sensitivity to LSD was apparently unaffected by pretreatment with α-methyl-p-tyrosine (AMPT).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 37 (1974), S. 311-321 
    ISSN: 1432-2072
    Schlagwort(e): Rats ; Ethanol ; Ethanol Reinforcement ; Acquisition ; Schedule-Induced-Polydipsia ; Ethanol Concentration
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Daily 6-h sessions were run during which each lever press by rats produced brief access to water, or to 8
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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