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Digitale Medien

Effectiveness of the intestinal polypeptides, IRP, GIP, VIP and motilin on insulin release in the rat (1974)

Turner, D. S. ; Etheridge, Lauraine ; Marks, V. ; [weitere]

Springer

Diabetologia 10 (1974), S. 459-463

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Details

ISSN: 1432-0428

Schlagwort(e): Intestinal hormones ; insulin release ; intestinal insulin releasing polypeptide (IRP) ; gastric inhibitory peptide (GIP) ; motilin ; vasoactive intestinal polypeptide (VIP) ; glucagon

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Intestinal insulin releasing polypeptide (IRP) and Gastric inhibitory polypeptide (GIP) have a similar effect on intravenous glucose tolerance in the rat. Both augment the insulin response to intravenous glucose and increase the rate of glucose disappearance. VIP and motilin have no discernible effect. Plasma insulin dose-response curves to IRP and GIP are similar; both peptides stimulate insulin release in the presence of small blood glucose increments. A direct comparison of the insulin releasing potency of IRP and GIP is not possible as the former is not yet available in pure form.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01221638

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