ISSN:
1432-0428
Keywords:
Intestinal hormones
;
insulin release
;
intestinal insulin releasing polypeptide (IRP)
;
gastric inhibitory peptide (GIP)
;
motilin
;
vasoactive intestinal polypeptide (VIP)
;
glucagon
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Intestinal insulin releasing polypeptide (IRP) and Gastric inhibitory polypeptide (GIP) have a similar effect on intravenous glucose tolerance in the rat. Both augment the insulin response to intravenous glucose and increase the rate of glucose disappearance. VIP and motilin have no discernible effect. Plasma insulin dose-response curves to IRP and GIP are similar; both peptides stimulate insulin release in the presence of small blood glucose increments. A direct comparison of the insulin releasing potency of IRP and GIP is not possible as the former is not yet available in pure form.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01221638
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