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  • 1970-1974  (12)
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Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Longitudinal Differentiation of Chromosomes (1973)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 7 (1973), S. 153-176 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.07.120173.001101
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  • 2
    Electronic Resource
    Electronic Resource
    Distribution of repetitious DNA in human chromosomes (1971)
    Springer
    Cellular and molecular life sciences 27 (1971), S. 964-966 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Studien von in situ DNS/RNS-Hybriden (oder Mischflüssigkeiten) zwischen RNS und verschiedenen Fraktionen von DNS und Metaphase-Chromosomen des Menschen ergaben, dass hauptsächlich die wiederholt vorkommende DNS-Fraktion C o t = 0 → 0.005 sich in der centromeren und telomeren Region befindet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02135776
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  • 3
    Electronic Resource
    Electronic Resource
    Chromosome homology in the climbing rats, genus tylomys (Rodentia: Cricetidae) (1973)
    Springer
    Chromosoma 42 (1973), S. 215-228 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The climbing rats (Tylomys spp.) have diploid numbers of 52 (T. panamensis), 42 (T. nudicaudus), 40 (T. n. gymnurus) and 36 (T. n. villai). Using G-band analysis we found that the variations are mainly of the Bobertsonian type, and practically all changes can be traced. G-banding also revealed that biarmed chromosomes with similar morphology may be composed of different components. Such conclusions were verified also by analysis of the chromosomes of interspecific hybrids. C-band staining showed that the constitutive heterochromatin of Tylomys is mainly located in the centromeric regions and the sex chromosomes, a situation similar to that of Microtus agrestis. In one specimen of T. panamensis, however, an additional terminal heterochromatic segment was found in one member of the large metacentric pair. Our data underline that in mammalian cytotaxonomy studies both C- and G-band (or C- and Q-band) techniques must be applied to gain maximal information.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320942
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  • 4
    Electronic Resource
    Electronic Resource
    Distribution of constitutive heterochromatin in mammalian chromosomes (1971)
    Springer
    Chromosoma 34 (1971), S. 243-253 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Using a special staining technique, a survey of the chromosomes of many mammalian species showed that constitutive heterochromatin is present in all cases and that the heterochromatin pattern appears to be specific and consistent or each chromosome and each taxon. Usually heavy heterochromatin is found in the centromeric areas, but terminal heterochromatin is not uncommon. Occasionally interstitial heterochromatin bands occur. In some species, such as the Syrian hamster and Peromyscus, many chromosome arms are completely heterochromatic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00286150
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  • 5
    Electronic Resource
    Electronic Resource
    Subdivision of the human Y chromosome (1974)
    Springer
    Human genetics 〈Berlin〉 24 (1974), S. 59-65 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Am menschlichen Y-Chromosom können mittels der Q-und C-Methoden 6 einzelne Abschnitte nachgewiesen werden, besonders wenn das Chromosom nicht stark kondensiert ist. Nach unseren Befunden bleibt der kurze Arm ungefärbt, während der lange Arm in 5 Abschnitte (Bänder) unterteilt werden kann: ein perizentrisches C-positives Band (Yq1), ein C-negatives Band Yq2, zwei C-positive Bänder Yq3 und Yq5, die gelegentlich in eine hellere und eine dunklere Zone unterteilt werden können und zwischen denen ein helles Band, Yq4, zu erkennen ist. Bei der Q-Methode bildet Uq4 den Spalt zwischen den beiden hell fluorescierenden Abschnitten. Die Befunde werden mikrodensitometrisch belegt. Das terminale Heterochromatin könnte durch eine Tandem-Duplikation entstanden sein.
    Notes: Summary The normal human Y chromosome was subdivided into 6 distinct bands by Q, C bandings and microdensitometric tracing. The best results were obtained from chromosomes not fully condensed. The results reveal that at late prophase the Y can be subdivided in 1 single unstained band in short arm 5 bands in the long arm. These 5 bands from centromere to telomere are: a pericentric C+ band Yq1; unstained band Yq2; C+ band Yq3; lightly stained band Yq4; and a C+ band Yq5. These observational results were substantiated by densitometric tracings. The Yq3 and Yq5 bands can sometimes be subdivided further into a dark and a light C+ zone. The Q band analysis indicates that the distal heterochromatin can be subdivided in two regions with the Yq4 band appearing as a lightly stained zone. We believe the terminal heterochromatin of the prevalent human Y represents a single tandem duplication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00281109
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  • 6
    Electronic Resource
    Electronic Resource
    Localization of repetitive DNA in the chromosomes of Microtus agrestis by means of in situ hybridization (1971)
    Springer
    Chromosoma 32 (1971), S. 224-236 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Heterochromatin in the European field vole, Microtus agrestis, was studied using a special staining technique and DNA/RNA in situ hybridization. The heterochromatin composed the proximal 1/4 of the short arm and the entire long arm of the X chromosome, practically the entire Y chromosome and the centromeric areas of the autosomes. By using the DNA/RNA in situ hybridization technique, repeated nucleotide sequences are shown to be in the heterochromatin of the sex chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00286011
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  • 7
    Electronic Resource
    Electronic Resource
    Arrangement of centromeres in mouse cells (1971)
    Springer
    Chromosoma 34 (1971), S. 73-87 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Applying a staining procedure which reveals constitutive heterochromatin to cytological preparations of the mouse (Mus musculus), one detects heterochromatin pieces at the centromeric areas of all chromosomes except the Y. The Y chromosome is somewhat heteropyenotic in general but possesses no intensely stained centromeric heterochromatin. The arrangement of the centromeric heterochromatin in interphase cells is apparently specific for a given cell type. In meiotic prophase, centromeric heterochromatin may form clusters among bivalents. From the location of the centromeric heterochromatin of the X chromosome in the sex bivalent, it is concluded that the association between the X and Y (common end) in meiosis is limited to the distal portions of the sex elements.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00285517
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  • 8
    Electronic Resource
    Electronic Resource
    Induction of chromosome banding in early stages of spermatogenesis by ethidium bromide (1973)
    Springer
    Chromosoma 44 (1973), S. 285-290 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Distinct chromosome banding of early meiotic prophase (leptotene through early pachytene) can he induced in male Chinese hamsters by injecting ethidium bromide and Actinomycin D intratesticularly for 4 hours and making acetic orcein squash preparations from minced testicular tissue. Zygotene pairing apparently starts from chromosome ends.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291022
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  • 9
    Electronic Resource
    Electronic Resource
    Evolutionary conservatism in arrangement of genetic material (1973)
    Springer
    Chromosoma 43 (1973), S. 211-224 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The diploid number of the Rhesus macaque, Macaca mulatta, is 42. All chromosomes are biarmed and all constitutive heterochromatins are centromeric. The diploid number of the African Green monkey, Cercopithecus aethiops, is 60. Again all chromosomes are biarmed, but seven pairs possess very short second arms which are heterochromatic. The heterochromatins of remaining chromosomes are centromeric. Using G-banding and deleting the heterochromatic short arms, the chromosomes of the African Green monkey can be artificially fused to reconstruct a karyotype of the Rhesus with only one pair of unmatched small metacentrics. In addition to the Robertsonian type of translocations, several sets of centromere-telomere translocations were found. The latter type of translocation reduced three arms into two. Thus the fundamental number can be changed by two mechanisms: growing extra heterochromatic arms and the centromere-telomere fusions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00483380
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  • 10
    Electronic Resource
    Electronic Resource
    Effects of ethidium bromide on mitosis and chromosomes: a possible material basis for chromosome stickiness (1974)
    Springer
    Chromosoma 47 (1974), S. 157-166 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract When two types of mammalian cells were treated with ethidium bromide for several hours, the mitotic figures showed no chromatid breaks or exchanges but a high incidence of sticky chromosomes. Electron microscopic examinations revealed that many chromosomes are connected by submicroscopic chromatin strands of various widths. Chromosome stickiness, therefore, is interpreted as entanglement of chromatin fibers between unrelated chromosomes, probably caused by abnormal condensation behaviors prior to mitosis. Presumably, chromatin breaks would occur when sticky chromosomes separate during anaphase. Such microscopically undetectable breaks expressed as various kinds of chromosomal aberrations in the next mitosis when the damaged cells were permitted to recover in the absence of ethidium bromide.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331803
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