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  • 1965-1969  (1)
  • 1955-1959  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 144 (1957), S. 65-82 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Mit Hilfe der Methode der manometrischen Bestimmung des O2-Verbrauches von proliferierenden Typhusbakterien wurde versucht, die qualitativen Unterschiede der zur Zeit auf dem deutschen Markt befindlichen Handelspeptone einschließlich der amerikanischen Präparate auszutesten. Durch eine gesonderte Betrachtung der Art des Atmungsanstieges, der Größe des O2-Verbrauches und dessen nach erfolgter Proliferation des Testkeimes maximal erreichte Höhe wurden die einzelnen Peptone hinsichtlich ihres Gehaltes an wachstumfördernden bzw. -hemmenden Stoffen untersucht. Während in—für die Proliferation unter streng aeroben Bedingungen — unterschwelligen Peptondosierungen (0,1%) nach einer kurzen, unerheblichen Keimvermehrung nur ein reiner Betriebsstoffwechsel auftritt, der sich in Form einer Ruheatmung Äußert, werden in den Peptonkonzentrationen von 0,5%, 1,0% und 2,0% Unterschiede in der Güte der einzelnen Peptone erkennbar. Bei Anwendung höherer Konzentrationen (3,0%) verschwinden die Unterschiede zwischen den einzelnen Präparaten fast völlig, ein Effekt, der ebenfalls durch Zusatz von Fleischextrakt auch bei niedrigeren Peptonkonzentrationen zu beobachten ist.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 46 (1959), S. 266-266 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 101 (1968), S. 123-130 
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The frequency of uv-induced S3-mutations (resistance to 3 γ Streptomycin/ml) in E. coli B/phr−/MC2 was not significantly increased by postincubation in NB with caffeine, though an increase is to be expected if caffeine would inhibit the dark repair of the S3-premutations. The frequency was even decreased by high (≧0,1%) caffeine concentrations (Fig. 1), which indicates an enhancement of the (caffeine-resistant) repair. This enhancement may be caused indirectly by the observed prolongation by caffeine of the lag phase which gives more time for repair. Also the strong photoprotection and (indirect) photoreversion of the S3-mutations in this (non-photoreactivable) strain were not influenced by caffeine-posttreatment (Fig. 2 and 3). Thus, the dark repair assumed to be stimulated by pre- or post-illumination would be of the caffeine-resistant type. The repair of S3-premutations occurring during post-treatment in saline was inhibited by caffeine (Fig. 4). Also the dark-reactivation of cells killed by uv was inhibited by caffeine in the NB-agarmedium (Fig. 5). It is assumed that the repair of S3-premutations going on in NB-suspended cells is due to a mechanism which is not or only weakly inhibitable by caffeine and which is different from the caffeine-sensitive mechanism working under hunger conditions (perhaps by excising uv-products). Since reactivation of killed cells is caffeine-sensitive but reversion of S3-premutations is caffeine-resistant in NB-cells the uv-induced lethal lesions must be different from the S3-premutations.
    Type of Medium: Electronic Resource
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