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  • Immunoscintigraphy  (2)
  • Industrial Chemistry  (2)
  • Lupus anticoagulants  (2)
  • (Ehrlich ascites cell membrane)  (1)
  • (Tumor cell)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Lack of effect of the Ca^2^+ ionophore A23187 on tumour cells
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 645 (1981), S. 177-182 
    Details
    ISSN: 0005-2736
    Keywords: (Tumor cell) ; Ca^2^+ permeability ; Ionophore A23187
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(81)90188-7
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Calcium permeability of Ehrlich ascites tumour cell plasma membrane in vivo
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 686 (1982), S. 27-35 
    Details
    ISSN: 0005-2736
    Keywords: (Ehrlich ascites cell membrane) ; Ca^2^+ permeability ; Energy depletion ; Ionophore ; Mitotic activity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(82)90148-1
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Anticardiolipin antibodies do not seem to be associated with APC resistance in vivo or in vitro (1995)
    Springer
    Annals of hematology 71 (1995), S. 195-198 
    Details
    ISSN: 1432-0584
    Keywords: Key words Anticardiolipin antibodies ; Lupus anticoagulants ; APC resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Anticardiolipin antibodies (aCL) or lupus anticoagulants (LA) have been found to exert an inhibitory action upon the activation and function of protein C, a natural coagulation inhibitor. Recently an in vitro phenomenon called resistance to activated protein C (APC resistance) has been described as the most frequent cause of hereditary thrombophilia. In order to see whether a positive association of APC resistance with aCL exists we examined plasma of 162 consecutive outpatients referred for thrombophilia screening. Further, the IgG fraction was isolated from plasma of two aCL-positive and LA-negative patients and of two aCL-negative healthy subjects by means of protein A affinity chromatography. Each of these isolates was mixed with normal plasma, and the APC resistance was assayed; 25/162 (15.4%) patients had confirmed abnormal APC resistance. Only 1/25 (4.0%) APC resistance-positive patients and 11/137 (8.0%) APC resistance-negative patients had positive IgG- and/or IgM-aCL (p=0.5, nonsignificant). In the in vitro test system the APC resistance ratio remained unaffected after addition of normal IgG or aCL-IgG fraction in the tested normal plasma and did not deviate from the range of buffer controls. These data do not suggest any association of aCL with abnormal APC resistance. aCL-IgG fractions from aCL-positive and LA-negative plasmas do not interfere with the APC resistance test system in vitro in low concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01910318
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Anticardiolipin antibodies do not seem to be associated with APC resistance in vivo or in vitro (1995)
    Springer
    Annals of hematology 71 (1995), S. 195-198 
    Details
    ISSN: 1432-0584
    Keywords: Anticardiolipin antibodies ; Lupus anticoagulants ; APC resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Anticardiolipin antibodies (aCL) or lupus anticoagulants (LA) have been found to exert an inhibitory action upon the activation and function of protein C, a natural coagulation inhibitor. Recently an in vitro phenomenon called resistance to activated protein C (APC resistance) has been described as the most frequent cause of hereditary thrombophilia. In order to see whether a positive association of APC resistance with aCL exists we examined plasma of 162 consecutive outpatients referred for thrombophilia screening. Further, the IgG fraction was isolated from plasma of two aCL-positive and LA-negative patients and of two aCL-negative healthy subjects by means of protein A affinity chromatography. Each of these isolates was mixed with normal plasma, and the APC resistance was assayed; 25/162 (15.4%) patients had confirmed abnormal APC resistance. Only 1/25 (4.0%) APC resistance-positive patients and 11/137 (8.0%) APC resistance-negative patients had positive IgG- and/or IgM-aCL (p=0.5, nonsignificant). In the in vitro test system the APC resistance ratio remained unaffected after addition of normal IgG or aCL-IgG fraction in the tested normal plasma and did not deviate from the range of buffer controls. These data do not suggest any association of aCL with abnormal APC resistance. aCL-IgG fractions from aCL-positive and LA-negative plasmas do not interfere with the APC resistance test system in vitro in low concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01910318
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Imaging rheumatoid arthritis joints with technetium-99m labelled specific anti-CD4− and non-specific monoclonal antibodies (1994)
    Springer
    European journal of nuclear medicine 21 (1994), S. 176-180 
    Details
    ISSN: 1619-7089
    Keywords: Anti-CD4 monoclonal antibody ; Anti-carcinoembryonic antigen monoclonal antibody ; Immunoscintigraphy ; Technetium-99m labelling ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A direct comparison of the joint-imaging properties of inflammation-specific- and non-specific monoclonal antibodies (Mabs) was possible in a patient suffering from long-standing, severe rheumatoid arthritis (RA). This patient received an anti-CD4− and an anti-carcinoembryonic antigen (anti-CEA) Mab, both labelled with technetium-99m, 9 days apart from each other. The anti-CD4 Mab was superior to the isotype-matched anti-CEA Mab in imaging inflamed joints. In the knee joint, the target-to-background ratio of the synovial membrane (SM) activity in comparison to that of adjacent large vessels was 1.22 (SM/muscle 1.55) for the anti-CD4 Mab and 0.53 (SM/muscle 0.92) for the anti-CEA Mab, in both cases 4 h after injection of the immunoglobulin. Since the CD4 antigen is present on the surface of T-helper lymphocytes and macrophages infiltrating the inflamed synovial membrane, imaging with the anti-CD4 Mab may allow more specific detection of inflammatory infiltrates in RA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00175768
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  • 6
    Electronic Resource
    Electronic Resource
    Imaging rheumatoid arthritis specifically with technetium 99m CD4-specific (T-helper lymphocytes) antibodies (1990)
    Springer
    European journal of nuclear medicine 17 (1990), S. 156-159 
    Details
    ISSN: 1619-7089
    Keywords: Immunoscintigraphy ; Technetium 99m-labelled antibodies ; CD4-specific (T-lymphocyte) antibodies ; Rheumatoid arthritis ; Localisation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract CD4 expressing T-lymphocytes are involved in the pathogenesis of rheumatoid arthritis, so the possibility of using radiolabelled CD4-specific antibodies to localise diseased joints was studied. Prospectively six patients with rheumatoid arthritis were investigated. Five of them received 200–300 μg of a 555 MBq technetium 99m CD4-specific antibody (MAX.16H5) and were examined with three phase bone scans. Max.16H5 (IgG1) was labelled according to the mercaptoethanol (Schwarz) method. Lymphocytes of one patient were isolated on a Ficoll-Hypaque gradient and labelled with the antibody in vitro. Scans were performed 1.5 h, 4 and 24 h post injection in anterior and posterior views. In all patients, diseased joints could be clearly imaged at as early as 1.5 h. The localisation of the diseased joints correlated (P〈0.01) with the clinical signs, with the early methylene diphosphonate (MDP) scan (P 〉 0.01) and only weakly with the late bone scan (P 〉 0.05). According to these data we conclude that99mTc-labelled CD4-specific antibodies specifically image actively diseased joints in rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00811445
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Gemeinsame Spurenanalyse von H2S und COS in SO2-haltigen Abgasen (1967)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 39 (1967), S. 945-948 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: In Gegenwart eines großen SO2-Überschusses ist die quantitative polarographische COS-Spurenbestimmung in Diäthylamin/Äthanol als Grundlösung möglich, wenn das SO2 ganz oder teilweise durch Braunstein oder Silicagel gebunden wird. COS und H2S lassen sich gemeinsam bestimmen, wenn die SO2-Menge in 25 ml Grundlösung etwa 5 mg SO2 nicht übersteigt. Die quantitative polarographische Analyse von H2S-Spuren in Gegenwart eines großen SO2-Überschusses gelingt in Hydrazinhydrat/Äthanol als Grundlösung.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330391603
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  • 8
    Electronic Resource
    Electronic Resource
    Beziehungen zwischen Gas - Flüssig - Verteilungskoeffizienten und Crackaktivität bei H +-Zeolithen (Alumosilicaten)Ausführliche Mitteilung an anderer Stelle. (1961)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 33 (1961), S. 442-442 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330330608
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