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  • 1
    Electronic Resource
    Electronic Resource
    Secretion of lipoprotein lipid and synthesis of fatty acids, cholesterol and triacylglycerol by hepatocytes of fasted-refed rats
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism 876 (1986), S. 494-499 
    Details
    ISSN: 0005-2760
    Keywords: (Rat hepatocyte) ; Cholesterol ; Fatty acid ; Lipid synthesis ; Lipoprotein lipid secretion ; Triacylglycerol
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2760(86)90036-6
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  • 2
    Electronic Resource
    Electronic Resource
    DNA-synthesizing T and non-T cells in chronic lymphocytic leukemia (1978)
    Springer
    Annals of hematology 37 (1978), S. 319-326 
    Details
    ISSN: 1432-0584
    Keywords: Chronische lymphozytische LeukÄmie ; T-Zellen ; Lymphatische S-Phase-Zellen ; DNA-synthetisierende Zellen ; Lymphatische T-Zellen in S-Phase ; Chronic lymphocytic leukemia ; T lymphocytes ; Lymphoid S-phase cells ; DNA-synthesizing cells ; S-phase T lymphoid cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 21 patients with chronic lymphocytic leukemia (CLL) and in 8 hematologically normal persons the number of DNA-synthesizing peripheral blood lymphocytes was investigated by autoradiographic techniques. The lymphocytes were differentiated by En-rosette tests into T and non-T lymphoid cells. The results show a normal number of proliferating T lymphoid cells and an increased number of proliferating non-T lymphoid cells in clinical stages O-I. Stages III–IV demonstrate a significant increase of the proliferation rate of both T and non-T lymphoid cells. The possible pathogenetic factors and the prognostic value of these results are discussed.
    Notes: Zusammenfassung Bei 21 Patienten mit chronischer lymphatischer LeukÄmie (CLL) und 8 Normalpersonen wurde die Anzahl der DNA-synthetisierenden peripheren Blutlymphozyten autoradiografisch untersucht. Die Lymphozyten wurden dabei mit Hilfe des EN-Rosettentests in T-Zellen und Nicht-T-Zellen differenziert. Es zeigt sich eine normale T-Zellproliferation und eine erhöhte Nicht-T-Zellproliferation im Stadium O-I. In den fortgeschritteneren Krankheitsstadien erfÄhrt die Proliferation für T- und Nicht-T-Lymphozyten eine signifikante Steigerung. Die Proliferation der T-Zellen ist im Stadium IV auf das ca. 20fache, die der Nicht-T-Zellen auf das ca. 50fache gesteigert. Auf die Möglichkeit zu prognostischen Aussagen wird hingewiesen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01007867
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Electron traps in wide-gap n-Hg0.3Cd0.7Te characterized by time-resolved photoconductivity (1993)
    Springer
    Applied physics 57 (1993), S. 427-430 
    Details
    ISSN: 1432-0630
    Keywords: 71.55 ; 72.20.Jv ; 72.40 ; 72.80.Ey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Time-resolved photoconductivity measurements have been used to characterize electron traps in wide-gap n-HgO0.3Cd0.7Te for the first time. The characterization was made possible by combining the time-resolved photoconductive data with the analytical method conventionally used in DLTS spectroscopy. Two electron traps were found in the band gap with 61 meV and 79 meV below the conduction band edge, their concentrations are 1.1×1013 cm−3 and 5.8×1011 cm−3, respectively. Compared with DLTS spectroscopy, this characterization method markedly simplifies sample preparation and experimental procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331781
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  • 4
    Electronic Resource
    Electronic Resource
    DNA-synthesizing T and non-T cells in bacterial infections (1980)
    Springer
    Annals of hematology 40 (1980), S. 151-155 
    Details
    ISSN: 1432-0584
    Keywords: Bakterielle Infektionen ; T-Zellen ; lymphatische S-Phase-Zellen ; Bacterial infections ; T cells ; S-phase lymphoid cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The results of autoradiographic determination of DNA-synthesizing lymphocytes (3H-thymidine) in 10 patients with bacterial infections were compared with results in 10 normal patients and contrasted with 23 CLL patients in different stages [12]. In patients with infectious diseases the absolute number of T cells was lower and the mean values of S-phase T cells and S-phase non-T cells was higher than in normal persons. In contrast to the patients with infections, CLL patients in stage 0–III have lower S-phase T cell values and higher S-phase non-T cell values. In stage IV, on the other hand, all DNA-synthesizing lymphocytes are increased.
    Notes: Zusammenfassung Es werden die Ergebnisse der autoradiographischen Bestimmung DNA-synthetisierender Lymphozyten (3H-Thymidin) bei 10 Patienten mit bakteriellen Infekten mit den Ergebnissen bei 10 gesunden Personen verglichen und den Resultaten bei 23 CLL-Patienten in verschiedenen Krankheitsstadien gegenübergestellt. Bei Patienten mit Infektionen lagen die Mittelwerte der T-Zellen niedriger, die der T-Zellen und Nicht-T-Zellen in der S-Phase höher als bei Normalen. Gegenüber Infektpatienten zeigen die CLL-Patienten früher Krankheitsstadien niedrigere S-Phase-T-Zellwerte und höhere S-Phase-Nicht-T-Zellwerte; im fortgeschrittenen Stadium sind alle DNA-synthetisierenden Lymphozyten vermehrt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01013698
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  • 5
    Electronic Resource
    Electronic Resource
    228. Intraarterielle Chemotherapie bei Lebermetastasen — Bolusinjektion vs. kontinuierliche Infusion (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 652-652 
    Details
    ISSN: 1435-2451
    Keywords: Intra-arterial chemotherapy ; Liver metastases ; Intraarterielle Chemotherapie ; Lebermetastasen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einer prospektiven randomisierten Studie wurde die Wirksamkeit der kontinuierlichen intraarteriellen Cytostatica-Therapie (FUDR) über eine implantierbare Pumpe (n =19) mit der Bolusinjektion (n= 17) verglichen bei isolierten nicht resektablen Lebermetastasen. Es fand sich folgendes Ergebnis: Ansprechrate bei den Pumpen 58% vs. 41% bei den Ports. Progression bei kontinuierlicher Infusion 10,5% vs. 29,5% bei Bolusinjektion. Die Toxicität war bei kontinuierlicher Cytostatica-Applikation mit 58% gegenüber 23,5% deutlich erhöht.
    Notes: Summary In a prospective randomized study, the effectiveness of continuous intra-arterial cytostatics therapy (FUDR) via an implantable pump (n=19) on isolated, nonresectable liver metastases was compared with bolus injection (n=17). The following results were found: there was a 58% response rate in the pump group vs 41% in the port group. Progression with continuous infusion was 10.5% vs 29.5% with bolus injection. The toxicity of continuous cytostatics application was distinctly higher (58% vs 23.5%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836827
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  • 6
    Electronic Resource
    Electronic Resource
    310. Die isolierte gastrointestinale Perfusion beim Schwein (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 711-711 
    Details
    ISSN: 1435-2451
    Keywords: Liver metastasis ; Regional chemotherapy ; Perfusion, isolated ; Perfusion with cytostatic drugs ; Lebermetastasen ; regionale Chemotherapie ; Perfusion, isoliert ; Cytostatika-Perfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die isolierte Leberperfusion bzw. intraarterielle Chemotherapie kann zwar bei Lebermetastasen colorectaler Carcinome beachtliche Erfolge erzielen; jedoch treten in his zu 60% der Fälle Lokalrezidive auf. Unser Ziel war es, ein Modell zur isolierten hochdosierten Cytostatica-Perfusion des Gastrointestinaltraktes zu erarbeiten. Die bisher an 58 Schweinen durchgeführten Untersuchungen zeigen die Durchführbarkeit der isolierten Perfusion des GI-Trakts mittels extracorporalem Kreislauf bei einem Leck von weniger als 4,5%. Die Aufnahme des Cytostaticums FUDR erfolgt in der Leber and im Intestinum. Die Maximumdosis ist 8 mg/kg KG.
    Notes: Summary Isolated liver perfusion and intra-arterial chemotherapy of liver metastases of colorectal carcinomas are considerably successful; however, local recurrences occur in up to 60% of all cases. Our aim was to work out a model of isolated perfusion of the gastrointestinal tract with high-dosage cytostatics. To date, research has been carried out on 58 pigs; the results demonstrate the feasibility of isolated perfusion of the GI tract by means of extracorporeal circulation. The leakage rate is than 4.5 %. The cytostatic agent FUDR is absorbed in. the liver and intestine (maximum dose 8 mg/kg body weight).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836908
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