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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 203 (1972), S. 197-209 
    ISSN: 1432-1459
    Keywords: Cerebral blood flow ; Brain stem lesion ; “Apallic” syndrome ; Head injury ; Anoxia, cerebral ; Reticular formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An 11 Autopsiefällen mit protrahierten Bewußtseinsstörungen (apallisches Syndrom) verschiedener Genese (8 Zustände nach gedecktem Schädel-Hirn-Trauma, 1 Patient mit postmeningitischer Sinusthrombose und 2 post-anoxische Encephalopathien) wurde die Reduktion der Hirndurchblutung (HDB) mit der Ausdehnung und Lokalisation der anatomischen Hirnschäden korreliert. Unter Anordnung der Patienten jeweils nach der Schwere und Ausdehnung der Hirnstammläsionen sowie nach den HDB-Werten wurde eine Rang-Korrelation nach Spearman durchgeführt, die eine hochsignifikante Korrelation zwischen diesen beiden Parametern ergab. Hingegen zeigten diese Fälle keine Beziehungen zwischen Schwere bzw. Ausdehnung der Läsionen in Telencephalon und Stammganglien und der HDB-Reduktion. Ein Patient mit ausgedehnter postanoxischer Zerstörung des Neocortex ohne Hirnstammläsionen bot eine mäßiggradige HDB-Reduktion. Die erhobenen Befunde weisen darauf hin, daß eine Reduktion der Hirndurchblutung sowohl durch ausgedehnte Schädigung des Hirnmantels als auch durch Funktionsausfall der Großhirnrinde infolge von Schädigungen auf tieferen Ebenen bedingt sein kann. Die Bedeutung der Formatio reticularis des Hirnstammes für die Funktion und Durchblutung der Hirnrinde wird hervorgehoben.
    Notes: Summary In 11 necropsy cases with prolonged states of unresponsiveness (“apallic syndrome”) of various origin (8 cases following closed head injuries, one patient with postmeningitic phlebothrombosis and 2 postanoxic encephalopathies) the decrease of cerebral blood flow (CBF) was correlated to the extent and pattern of the anatomical lesions. Arranging the patients according to the severity and pattern of brain stem damage and according to the CBF values a Spearman rank correlation resulted in a highly significant relationship between these two parameters. By contrast, the extent of damage to the telencephalon and basal ganglia did not correlate to the CBF reduction in these cases. One patient with extensive neocortical destruction without damage to the brain stem had moderately decreased CBF. The data indicate that CBF reduction may result from both extensive destruction of the cerebral pallium and from states in which the cerebral cortex is out of function due to damage at lower levels. The importance of the reticular formation in the brain stem for the function and perfusion of the cerebral cortex is stressed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 234 (1987), S. 9-13 
    ISSN: 1432-1459
    Keywords: Cerebral blood flow ; 133Xe ; Exercise ; Autoregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Regional cerebral blood flow (rCBF) of the left hemisphere was measured in 12 healthy young men at rest and during physical work on a bicycle ergometer in the supine position at work-load levels of 25 W or 100 W using the intravenous 133Xe method. Regional mean cerebral blood flow, regional gray-matter flow, and relative gray-matter weight was determined for six regions of interest. Arterial blood pressure, pulse frequency and expiratory CO2 concentration were recorded. Cerebral blood flow in all regions was significantly (P〈0.001) higher during exercise than at rest. The increase in the 100 W group (24.7%) was significantly (P〈0.05) greater than in the 25 W group (13.5%), but resting blood flow levels and alveolar CO2 concentrations were also different in both groups. Mean arterial blood pressure, pulse frequency and alveolar CO2 concentrations, but not arterial pCO2, were significantly higher during exercise and there was a faster washout of whole-body xenon. The CBF increase was interpreted as a combined effect of elevated systemic blood pressure and functionally activated brain metabolism. There was no evidence of impaired cerebral autoregulation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 335 (1990), S. 131-137 
    ISSN: 1434-601X
    Keywords: 05.45.±b ; 03.65.−w
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Energy levels of a square well containing δ-function barriers on a Cantor set are analysed. According to the standard tests the spectrum has the characteristics of quantum chaotic behaviour. A discussion on the connection between the spectrum, the wave functions and the exceptional points in the case of quantum chaos is given.
    Type of Medium: Electronic Resource
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