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  • Cholecystokinin  (2)
  • 1,25-Dihydroxyvitamin D  (1)
  • Ambient pH signalling  (1)
  • Amino acid transport  (1)
  • Atypical antipsychotics  (1)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/General Subjects 675 (1981), S. 46-61 
    ISSN: 0304-4165
    Keywords: (Rat pancreas) ; Adenylate cyclase kinetics ; C-terminal octapeptide ; Cholecystokinin ; Cholera toxin ; Guanine nucleotide
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 1055 (1990), S. 207-216 
    ISSN: 0167-4889
    Keywords: (Pancreatic acinar cell line AR 4-2 J) ; Cholecystokinin ; Cholecystokinin degradation ; Internalization-sequestration
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Schizophrenie ; Typische Antipsychotika ; Atypische Antipsychotika ; Umstellung ; Keywords Schizophrenia ; Conventional antipsychotics ; Atypical antipsychotics ; Conversion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The introduction of atypical antipsychotics has presented new options for the pharmacological treatment of schizophrenic patients. It is assumed that in the near future, neuroleptic medication will shift from conventional to atypical antipsychotics for an increasing number of patients. The present article addresses guidelines for the conversion from conventional to atypical neuroleptics in inpatient and outpatient settings.
    Notes: Zusammenfassung Mit der Einführung der atypischen Antipsychotika haben sich neue Möglichkeiten in der pharmakotherapeutischen Behandlung schizophrener Patienten ergeben. Es ist anzunehmen, dass in den folgenden Jahren viele weitere Patienten von typischen auf atypische Präparate umgestellt werden. Der vorliegende Artikel befasst sich mit stationären und ambulanten Richtlinien zur Umstellung von typischen Neuroleptika auf atypische Antipsychotika. Diskutiert werden Möglichkeiten der Identifizierung geeigneter Kandidaten, Empfehlungen bei der Auswahl des atypischen Antipsychotikums und praktische Vorgehensweisen bei der Umstellung. Ergänzend werden Dosierungsrichtlinien der einzelnen atypischen Antipsychotika, mögliche Entzugssyndrome und andere Komplikationen des Präparatewechsels sowie substanzspezifische Aspekte der Umstellung dargestellt. Ein letztes Kapitel befasst sich mit den notwendigen psychotherapeutischen Interventionen, die im Rahmen einer Umstellung der antipsychotischen Medikation beachtet werden sollten.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 122 (1979), S. 201-205 
    ISSN: 1432-072X
    Keywords: Amino acid transport ; Yeast genetics ; Multiple drug resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In order to obtain strains of Saccharomycopsis lipolytica impaired in the active transport of l-lysine, mutants resistant to a mixture of l-canavanine, l-4-5-transdehydrolysine and l-S-amino ethylcysteine, taken either all three or two by two, were isolated. These compounds were shown previously to be competitive inhibitors of l-lysine uptake. The resistance patterns and excretion capacity of the mutants were established. All mutants behaved as monogenic. Recombination tests indicated that four genes at least were involved. All mutants were impaired in both high and low affinity l-lysine transport systems. Several hypotheses on the functions of these genes are put forward and discussed.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1617-4623
    Keywords: Key wordsYarrowia lipolytica ; Saccharomyces cerevisiae ; Ambient pH signalling ; Signal transduction ; Transmembrane protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In Yarrowia lipolytica, the transcription factor Rim101p mediates both pH regulation and control of mating and sporulation. Like its homologues PacC of Aspergillus nidulans and Rim101p of Saccharomyces cerevisiae, YlRim101p is activated by proteolytic C-terminal processing, which occurs in response to a signal transduced by a pathway involving several PAL gene products. We report here the cloning and sequencing of two of these genes, PAL2 and PAL3. PAL2 encodes a putative 632-residue protein with six possible transmembrane segments, which differs from the transmembrane proteins Rim9p of S. cerevisiae and PalI of A. nidulans, but is homologous to A. nidulans PalH and to the product of the ORF YNL294c, a predicted polypeptide of unknown function in S. cerevisiae. PAL3 encodes an 881-residue polypeptide that is homologous to PalF of A. nidulans and to a newly identified putative polypeptide of S. cerevisiae. Both PAL2 and PAL3 are expressed constitutively, regardless of ambient pH. Mutations in these genes affect growth at alkaline pH and sporulation in both Y. lipolytica and in S. cerevisiae. They affect invasiveness of haploid strains in S. cerevisiae only, and conjugation in Y. lipolytica only. These results highlight the conservation of the Pal pathway initially described in A. nidulans.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-9949
    Keywords: Lymphoma ; Hypercalcemia ; 1,25-Dihydroxyvitamin D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report two patients with non-Hodgkin's lymphoma in whom hypercalcemia and elevated 1,25 dihydroxyvitamin D (1,25-(OH)2D3) levels developed in the absence of any lytic bone lesions. Hypercalcemia responded only transiently to glucocorticoids which were ill tolerated. Intravenous APD administration was needed to circumvene hypercalcemia. Humoral hypercalcemia of malignancy is discussed. Our cases confirm that hypercalcemia associated with elevated 1,25-(OH)2D3 may occur in malignant lymphoma.
    Type of Medium: Electronic Resource
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