ISSN:
1432-1041
Keywords:
16α-gitoxin
;
16-acetyl-16α-gitoxin
;
ouabain
;
digitoxin
;
albumin binding
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary The binding of semi-synthetic (16α-gitoxin and its 16-acetate) and naturally occurring cardioactive glycosides (digitoxin, ouabain) to human serum albumin was studied using equilibrium dialysis, ultracentrifugation and gel filtration. 16α-gitoxin was 75% bound and its 16-acetate 95%. The percentage binding of digitoxin and ouabain was in good agreement with values reported in literature.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00562939
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