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  • 79.60.Bm  (1)
  • Albumin  (1)
  • Dehydration therapy  (1)
  • Hereditary spherocytosis  (1)
  • 1
    ISSN: 0009-8981
    Keywords: Calcium uptake ; Hereditary spherocytosis ; Red cell calcium ; Reticulocytosis ; Splenectomy
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0630
    Keywords: 71.25.Hc ; 74.72.Hs ; 79.60.Bm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Core-level X-ray photoelectron-diffraction patterns have been measured from cleaved Bi2Sr2CaCu2O8+δ (001) surfaces for all elements present in this compound. The incommensurate modulation alongb ([010]) leads to a strong inequivalence ofa- andb-directions for Bi, Sr and Cu photoelectrons, while Ca and O emission show less effect. Ultraviolet-photoemission experiments recording the emission intensity at the Fermi energy over a large solid angle are also presented, providing a direct mapping of the Fermi surface. Ac(2×2) superstructure is observed on the Fermi surface suggesting antiferromagnetic correlations within the Cu−O planes. The effects of the lattice modulation are clearly observable at the Fermi energy, and they are enhanced for binding energies higher than a few tens of meV.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 138 (1996), S. 1050-1056 
    ISSN: 0942-0940
    Keywords: Dehydration therapy ; early surgery ; patients management ; severe subarachnoid haemorrhage ; vasospasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We prospectively analysed treatment results in patients with severe subarachnoid haemorrhage (SAH) who underwent early aneurysm surgery, and were managed by dehydration therapy. We studied a total of 31 patients with poor-grade SAH including 18 in grade IV, and 13 in grade V according to the WFNS classification system. Patients who were older than 70 years of age, or those with an intracerebral haemorrhage or absent brainstem response were excluded from this study. At surgery, clot evacuation from the peribrainstem cisterns with/without external decompression was performed following obliteration of the aneurysmal neck. In the early postoperative period, patients were maintained in negative water balance using osmotic diuretics. When delayed ischaemic deficits had manifested themselves, the pulmonary wedge pressure and/or central venous pressure was immediately increased by the rapid injection of albumin until hypovolaemia reverted to normovolaemia with the continuous administration of dobutamine. The outcome at 3 months was good recovery in 16 (52%) patients, moderate disability in 3 (10%), severe disability in 5 (16%), a vegetative state in 1 (3%), and death in 6 (19%). We thought that early aneurysm surgery and postoperative dehydration therapy in the acute stages of brain oedema resulting from primary brain damage are effective in the treatment of patients with severe SAH but reversilbe primary brain damage.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pharmacy world & science 11 (1989), S. 87-91 
    ISSN: 1573-739X
    Keywords: Albumin ; Clearance ; Distribution ; Midazolam ; Models, theoretical ; Pharmacokinetics ; Protein binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The effects of altered albumin distribution on the apparent volume of distribution (V) and the apparent elimination rate constant (k) of drugs were investigated by a simulation analysis. The Equations derived by Øieet al. were modified for this purpose. Within the range observed in normal healthy subjects and patients, the change in albumin distribution significantly affectedV of drugs but, in general, notk. For drugs with more than 90% plasma-protein binding,V changed by more than 100%. The change in plasma-protein binding caused by an altered albumin distribution produced a greater effect onV than that caused by an altered albumin amount. These results suggest that albumin distribution is an important factor in controlling the kinetics of drugs which are highly bound to plasma protein. This is illustrated using midazolam as an example.
    Type of Medium: Electronic Resource
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