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  • ACTH/MSH(4-9) analog HOE 427  (1)
  • EEG power spectra  (1)
  • Fatty acids  (1)
  • 1
    ISSN: 0196-9781
    Keywords: ACTH/MSH(4-9) analog HOE 427 ; Hormonal effects ; Quality of sleep ; Sleep EEG ; Slow wave sleep
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Bretazenil ; Sleep EEG ; Cortisol ; Growth hormone ; Prolactin ; GABA benzodiazepine receptor ; EEG power spectra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Preclinical data suggest that the imidazo-diazepinone derivative bretazenil (Ro 16-6028) has anxiolytic and anticonvulsant properties with only weak sedative effects. We examined the influence of oral administration of 1 mg bretazenil on the sleep EEG and the concomitant nocturnal secretion of cortisol, growth hormone and prolactin in ten healthy young men. After bretazenil we found a significant increase in stage 2 sleep and a significant reduction in stage 3 sleep. REM latency was prolonged. Spectral analysis of sleep-EEG power revealed a decrease in delta and in theta power and an increase in sigma power. We found no significant influence on sleep onset latency or on intermittent wakefulness. Bretazenil prompted a significant decrease in cortisol secretion and a significant increase in prolactin release. It had no major influence on growth hormone secretion.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-072X
    Keywords: Gemmobacter gen. nov. ; Gemmobacter aquatilis sp. nov. ; Blastobacter ; Blastobacter aggregatus ; Phylogeny ; Taxonomy ; 16S rRNA cataloguing ; Fatty acids ; Plasmids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Blastobacter aggregatus and a Blastobacter-like isolate (IFAM 1031) were analysed by the 16S ribosomal RNA cataloguing approach in order to determine their phylogenetic position. Both phenotypical similar organisms are members of the alpha-subdivision of purple phototrophic bacteria and their non-phototrophic relatives but they are not closely related: B. aggregatus clusters with Agrobacterium tumefaciens and Rhizobium species; the unnamed strain displays a moderate relationship to members of Rhodobacter and Paracoccus denitrificans, with which is shares the character of a nicked 23S rRNA. Although the budding isolate IFAM 1031 resembles members of Blastobacter phenotypically, in the broad DNA G+C content and in the fatty acid pattern, a unique set of characters was found which allows description of the isolate as the typus of a new genus for which Gemmobacter gen. nov. is proposed, with G. aquatilis sp. nov. as the type species. G. aquatilis harbors at least two plasmids of different size and unknown function.
    Type of Medium: Electronic Resource
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