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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 56 (1978), S. 1213-1216 
    ISSN: 1432-1440
    Keywords: Athyropexinemia ; Cardiomyopathy ; Hypertrophic ; Heart defects ; Congenital ; Hereditary diseases ; Combined thyroxine-binding protein thyropexin deficiency ; Athyropexinämie ; Erbgang ; Erbanomalien, kombinierte ; Kardiomyopathien, hypertrophische, kongenitale ; Erbgang ; Thyropexinmangel, erblicher ; Thyroxin-bindendes Globulin ; Kombinierter Erbgang Thyropexinmangel und Kardiomyopathien
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei einem Patienten mit hereditärer hypertrophischer obstruktiver Kardiomyopathie (HOCM) fehlt das thyroxinbindende Globulin („Thyropexin“) völlig. Obwohl der Thyroxinspiegel extrem niedrig ist und die Schilddrüse eine erhöhte Jodavidität aufweist, erscheint der Patient klinisch euthyreot. Ein ähnliches Syndrom hat Ingbar 1961 beschrieben. Bei einem Onkel des Patienten und bei zwei Neffen, von denen einer eine asymmetrische Septumhypertrophie (ASH) aufweist, besteht eine Athyropexinämie; bei der Mutter, bei einer Schwester und einer Kusine ist das Thyropexin vermindert. Die Mutter leidet an einer hypertrophischen Kardiomyopathie (HCM).
    Notes: Summary A twenty-five years old man was found to have simultaneous total deficiency of thyroxine-binding globulin (“thyropexin”) and hereditary hypertrophic obstructive cardiomyopathy (HOCM). The thyroxine-binding capacity (RT3U), thyroid hormone levels, PB127I, PB131I and TBG (RIA) in serum were very low and TBG cap was zero. Trapping of radioiodine in the thyroid was enhanced. Clinically, the patient appeared euthyroid. The case seems to be similar to another one described earlier by Ingbar. An investigation of the family showed that in one uncle and two nephews of the patient thyropexin was absent whilst the mother, one sister and one female cousin had partial thyropexin deficiencies. One of these nephews also suffers from asymmetric septal hypertrophy (ASH), the mother of the propositus has a non-obstructive hypertrophic cardiomyopathy (HCM).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Ernährungswissenschaft 37 (1998), S. 18-22 
    ISSN: 0044-264X
    Keywords: Key words Iodine – urinary iodine – iodide substitution – goiter prevention – iodide tablets ; Schlüsselwörter Iod – Uriniod – Substitution mit Iod – Kropfprophylaxe – Iodidtabletten ; Abbreviation indexd = day ; h = hour ; μg = micorgramm ; n = number of cases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Zusammenfassung 25 schilddrüsengesunde Probanden wurden in zwei Gruppen aufgeteilt. Jeder Teilnehmer in Gruppe A erhielt 8 Wochen lang 200 μg Iod täglich in Form von Diiodtyrosin, also insgesamt 7×200 μg/Woche, in Gruppe B 1.500 μg Iodid einmal pro Woche. Die wöchentliche Iodausscheidung im Urin betrug in Gruppe A zusätzlich zur basalen Ausscheidung in der 8. Woche ca. 67% der durch Tabletten aufgenommenen Iodmenge von 7×200 μg/Woche. In Gruppe B betrug die renale Iodausscheidung in der 8. Woche ca. 65% der durch Tabletten aufgenommenen Iodmenge. Zwischen beiden Formen der Iodzufuhr besteht besteht somit kein bedeutender Unterschied.
    Notes: Summary 25 euthyroid volunteers were divided into two groups. Each participant of group A received 200 μg iodine in the form of diiodotyrosine per day for a period of eight weeks, i.e. 7×200 μg iodine/week. Each participant of group B received 1.500 μg iodide once a week for a period of eight weeks. In addition to the basal excretion of iodine with the collected urine, the excretion values in group A amounted to 67% of the applied dose in the eighth week. In group B, the excretion values amounted to 65% of the applied dose in the eighth week. Hence, no significant difference between both groups was found.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 11 (1928), S. 1252-1255 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 79 (1967), S. 311-311 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 23 (1957), S. 717-738 
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Deoxyribonucleic acid has been extracted from phage D4 by different techniques: compression, heating, alkalinization, etc. The corresponding aqueous solutions have been studied as functions of different physical factors (concentration, pressure temperature, pH, ionic strength, etc.) by viscometry, by flow birefringence, and by ultraviolet absorption. The biological activity of the phages in the course of these different treatments has also been determined. All the solutions studied were strongly polydispersed. For each one, the mean DNA particle length, the optical anisotropy, and the degree of polydispersion have been determined. These results have been compared to those of DNA of calf thymus. The disagreement between the particle dimensions of the phages and those of free DNA particles has been discussed, and an interpretation is proposed for the apparent contradictions.
    Notes: L'acide desoxyribonucléique est extrait du phage D4 par différentes techniques: compression, chaffage, alcalinisation, etc. Les solutions aqueuses correspondantes sont étudiées, en fonction de divers facteurs physiques (concentration, pression, température, pH, force ionique...) par viscosité, par biréfringence d'écoulement et par absorption UV. L'activité biologique des phages au cours des différents traitements est également déterminée. Toutes les solutions étudiées sont fortement polydispersées. Pour chacune d'elles on a déterminé la longueur des particules d'ADN les plus fréquentes, leur anisotropie optique et leur taux de polydispersion. Les résultats obtenus sont comparés à ceux relatifs à l'ADN du thymus de veau. La question de la compatibilité des dimensions des particules du phage et de celles beaucoup plus grandes des particules de l'ADN libéré est discutée et une interprétation est proposée en vue de lever les contradictions apparentes.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 6 (1967), S. 356-357 
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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