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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 110 (1997), S. 63-68 
    ISSN: 1437-1596
    Keywords: Key words Sudden infant death ; Lymph nodes ; Thymus ; Histology ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract In 50 cases of sudden infant death cervical, paratracheal and lung hilar lymph nodes, the thymus and the spleen were investigated by histology and immunohistochemistry (CD 20, 21, 45RO). The cases were divided into 3 groups based on autopsy findings including extensive histology: A – without pathological changes (N = 12), B – with minimal to intermediate inflammation (N = 23) and C – with severe inflammation (N = 15). In accordance with previous results the frequency of “pathological” lymph node changes, such as paracortical lymphoid hyperplasia and variegated hyperplasia of the pulp increased from group A to group C. The B-cell antigens reacted accordingly. A pronounced lymphodepletation of the thymus as a sign of a long lasting stimulation of the T-cell system was also observed increasingly from group A to C. In summary, in none of the cases results obtained were indicative of a defect of the T- or B-cell system. The results in group A seem to indicate that changes in the reaction pattern of the lymphoid tissues could be a more sensitive method of detection of early stages of inflammation than local histology.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-5196
    Keywords: Key words Cyanogen compounds ; Lethal oral ; intoxication ; Ability to act ; Schlüsselwörter Cyan-Verbindungen ; Tödliche orale Intoxikation ; Handlungsfähigkeit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Einschätzung der Handlungsfähigkeit eines tödlich Vergifteten kann bei der Tatrekonstruktion sehr bedeutsam sein, insbesondere bei der Frage „Selbst- oder Fremdbeibringung des Giftes“. Klinische Publikationen gehen hierauf kaum ein. Deshalb wurden 27 Fälle tödlicher oraler Intoxikationen mit Cyan-Verbindungen der rechtsmedizinischen Institute Würzburg, Hamburg, München, Berlin (FU), Tübingen, Essen und Leipzig, bei denen eine Aussage zur Handlungsfähigkeit des später Verstorbenen möglich war, sowie die dazugehörigen polizeilichen und staatsanwaltschaftlichen Akten unter dieser Fragestellung ausgewertet. Ergebnis: in der Mehrzahl der Fälle betrug die Handlungsfähigkeit nur wenige Sekunden bis maximal 1 bis 2 Minuten. Im Untersuchungsgut und in der Literatur kamen allerdings auch Fälle vor, bei denen die Handlungsfähigkeit über ca. 5 bis 10 min erhalten war. Die Ergebnisse der Arbeit sollen dem Gutachter als Leitlinie bei der Klärung einschlägiger Fälle dienen.
    Notes: Abstract An accurate assessment of the duration of the ability to act of a victim of lethal poisoning can be of crucial importance in reconstructing the cause of the poisoning, especially in determining whether the poison was taken by the victim or given by another. Clinical studies have scarcely dealt with this problem. We therefore investigated 27 cases of lethal oral intoxication with cyanogen compounds on file at the university institutes of forensic medicine in Würzburg, Hamburg, Munich, Berlin (Free University), Tübingen, Essen and Leipzig with regard to the victim’s postintoxication ability to act. In addition we examined the records of the respective police and prosecuters offices as well as the relevant literature. In most cases the ability to act lasted only a few seconds to a maximum of 1–2 min. However, in some of the 27 cases the ability to act lasted for 5–10 min, a finding which agrees with reports in the literature. The present study is intended to provide forensic expert witnesses with guidelines for clarifying similar cases of lethal oral intoxication.
    Type of Medium: Electronic Resource
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