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  • 1
    Electronic Resource
    Electronic Resource
    Intramyocardial microarteriopathy (1980)
    Springer
    Virchows Archiv 388 (1980), S. 289-311 
    Details
    ISSN: 1432-2307
    Keywords: Intramyocardial microarteriopathy ; Age ; Frequency ; Risk factors ; Functional significance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Two basic types of arterial vessels can be distinguished in the myocardium. a) Compacta or Ventricular Wall Type. Intramyocardial microarteries with ring musculature of the media. b) Papillary Muscle Type. Arteries with longitudinal musculature arranged as bundles in the broad media. 2. The manifestation of intramyocardial microarteriopathy differs in these vessel types. PAS-positive and elastica-rich cushion-like thickening of the intima mainly occurs in the compacta type. Arterial vessels of the trabecular portion additionally show hyperelastosis of intima and media. The degenerative lesions of the papillary muscle type are characterized by early degeneration of the smooth muscle cells and hyperfibroelastosis of intima and media. 3. Pathological vascular lesions in the compacta and papillary muscle type occur more frequently in the left ventricle, and increase with age. 4. Slight and medium lesions are in the majority. Severe vascular changes are seen in the 7th to 9th decade in about 5–10% (compacta type) and in 30–35% (papillary muscle type) respectively. 5. Hypertension seemed to raise the frequency of slight and medium lesions in the compacta type vessels. In the papillary muscle type the degenerative lesions frequently extend from the top to the bottom of the papillary muscles. 6. No significant difference between frequency and severity of vascular lesions in diabetics and in the control group could be demonstrated. 7. It appears that pathological vascular lesions occur less frequently in compacta type vessels in cases of high-grade stenosis due to extramural coronary artery sclerosis. 8. Impairment of the quality of myocardial circulation is only encountered in the presence of severe pathological vascular lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00430860
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    When should treatment of acute experimental pancreatitis be started? (1988)
    Springer
    Research in experimental medicine 188 (1988), S. 123-129 
    Details
    ISSN: 1433-8580
    Keywords: Acute experimental pancreatitis ; Sodium taurocholate ; Pancreatic enzymes ; Pancreatic morphology ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sodium taurocholate pancreatitis in the rat is a frequently used experimental model for evaluating therapeutical regimes in this disease. It is, however, uncertain when treatment should be started, as the early phase of this experimental model and thus the time when the pancreatitis really develops is unknown. Serum and pancreatic enzymes, as well as pancreatic morphology, were therefore studied 5, 30, and 60min after induction of sodium taurocholate pancreatitis. It was found that increase in serum enzymes and decrease in pancreatic enzymes and morphological changes characteristic for acute pancreatitis develop as early as 5 and 30 min after induction of pancreatitis. Thus, therapy in this model may be started shortly after induction of acute pancreatitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01852268
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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