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  • 1
    Electronic Resource
    Electronic Resource
    Somatic fusion for combining virus resistances in Solanum tuberosum L. (1993)
    Springer
    Theoretical and applied genetics 85 (1993), S. 863-867 
    Details
    ISSN: 1432-2242
    Keywords: Potato ; PYX ; PVY ; Protoplasts ; Somatic hybrids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Dihaploid genotypes of potato, containing the dominant allele for extreme resistance to PVX and/or PVY, were used in a fusion program in order to analyze the behaviour of the two monogenetic resistances after fusion. Eighteen different fusion combinations were performed and regenerated hybrids were tested by ELISA for their virus resistance. In most of the combinations an addition of the two qualities was found, but a few deviating clones were observed. The possible reasons for the phenotypic disappearance of resistant alleles are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225030
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Interaction between cytoplasmic composition and yield parameters in somatic hybrids of S. tuberosum L. (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 873-878 
    Details
    ISSN: 1432-2242
    Keywords: Potato ; Somatic fusion ; Cytoplasm Starch ; Variability ; Field evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The nuclear and cytoplasmic composition of five different fusion combinations, consisting of up to 50 hybrid regenerants each, was characterized by RFLP analysis. Simultaneously, the hybrid clones of four fusion combinations were evaluated in field experiments for yield and starch content. Predominantly complete chloroplast segregation was found with a 1∶1 ratio, in all but one fusion combination. Mitochondria, in contrast revealed up to 75% recombination, as proven by the partial addition of parental banding patterns and the altered assignment of the same genotypes with different probes. Newly occuring DNA bands were also indicative of rearrangements in the mitochondrial genome. Correlations between RFLP data and field parameters were calculated. Deviating RFLP patterns of the nuclear genome did not influence yield parameters. Also the assignment of hybrids to different chloroplast genotypes did not affect yield or starch content. However, mitochondrial types could be distinguished with respect to starch content and tuber yield. The more thorough analysis of mitochondrial composition, with different probes homologous to coding regions, revealed a relationship between the homogeneity of the mt genome and the yield level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224512
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    267. Hyperparathyreoidismus nach Nierentransplantation unter Immunsuppression mit Cyclosporin A (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 674-674 
    Details
    ISSN: 1435-2451
    Keywords: Renal transplantation ; Cyclosporin A ; Hyperparathyroidism ; Nierentransplantation ; Cyclosporin A ; Hyperparathyreoidismus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei Patienten mit Parathyreoidektomie nach erfolgreicher Nierentransplantation wurden klinischer Verlauf and Laborwerte analysiert and hinsichtlich der Immunsuppression miteinander verglichen (Azathioprinn=6/Cyclosporin An=9). Die Cyclosporin-Gruppe zeigte ausgepräg-te Hypercalcaemie, Hypophosphataemie, Anstieg von alkalischer Phosphatase and Parathormon and erhöhte Cyclosporin-Blutspiegel. Eine Interaktion zwischen Cyclosporin A and Parathormon wird vermutet, die die Rückbildung des sekundären Hyperparathyreoidismus hemmt and so eine hochaktive renale Osteopathie unterhält.
    Notes: Summary Clinical course and laboratory tests were analyzed in patients with parathyroidectomy after successful renal transplantation and compared with respect to type of immunosuppression [azathioprine (n=6) versus cyclosporin A (n=9)j. The cyclosporin group showed marked hypercalcemia, hypophosphatemia, increase of alkaline phosphatase and parathormone, and elevated cyclosporin blood levels. We suspect that there is an interaction between cyclosporin A and parathormone that inhibits the regression of secondary hyperparathyroidism, thus leading to highly active renal osteopathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836865
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    Paper (German National Licenses)
    Fulltext
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