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  • 1
    Electronic Resource
    Electronic Resource
    Involvement of α-adrenoceptors in the excitatory effect of the A2 adenosine receptors agonist 5′-N-ethylcarboxamidoadenosine (NECA) on cardiac automaticity in the isolated right ventricle of the rat (1994)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 350 (1994), S. 632-637 
    Details
    ISSN: 1432-1912
    Keywords: Cardiac automaticity ; Adenosine receptors ; α-adrenoceptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of the non-selective A2 adenosine receptor agonist 5′-N-ethyl-carboxamidoadenosine (NECA) were studied on ventricular automaticity induced by a local injury in the isolated right ventricle of the rat. In concentrations ranging from 0.1 to 100 nM, NECA significantly increased ventricular automaticity. This effect was not apparent when the nonselective α-adrenoceptor blocker phenoxybenzamine was present at a concentration of 10 μM, which antagonizes both α1-and α2-adrenoceptors, as well as when rats were pretreated with reserpine. In non-reserpinized rats, the excitatory effect of NECA was also abolished in the presence of the selective α1-adrenoceptor antagonist prazosin, but not in the presence of the α2-adrenoceptor antagonist idazoxan. In reserpinized rats, the excitatory effect of NECA was restored in the presence of the non specific α-adrenoceptor agonist phenylephrine as well as in the presence of the selective α1-adrenoceptor agonist amidephrine but not in the presence of the selective α2-adrenoceptor agonist clonidine. These results suggest that the excitatory effect of NECA on ectopic ventricular automaticity is dependent on endogenous catecholamines and that α-adrenoceptors of type 1 are, in some way, involved in this effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169368
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  • 2
    Electronic Resource
    Electronic Resource
    Inflammatory aneurysm of the abdominal aorta: role of ultrasonography (1993)
    Springer
    European radiology 3 (1993), S. 333-336 
    Details
    ISSN: 1432-1084
    Keywords: Aneurysm ; Aorta ; Inflammatory aneurysm ; Ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract During a 5-year period 229 aneurysms of the abdominal aorta were identified by ultrasonography (US) and subsequently submitted to CT. Of these, 41 were seen to be of the inflammatory type on the grounds of the CT scans, confirmed in 29 cases by surgical findings. The patients were 38 men and 3 women, mean age 64.9 years. US, performed using both 3.5 and 5 MHz probes, revealed the inflammatory nature of the aneurysm in 33 of 41 cases (80.5%). In the remaining cases a correct diagnosis could not be determined because of obesity and/or the distal location of the lesion. Regarding the complications associated with the inflammatory nature of the aneurysm (considered only in those cases submitted to surgery) US revealed a good diagnostic accuracy for ureteral involvement (7/7 cases detected, no false positives). Caval involvement was also correctly identified in 6 of 8 cases, although overestimated in 3 of 21. Both of these complications were correctly detected by CT in all cases. Neither US nor CT furnished reliable signs regarding duodenal and colonic involvement (surgically proven in 4 of 29 cases). US proved effective in detecting the inflammatory nature of the aneurysm. If surgery is considered, CT seems mandatory for a correct assessment of the complications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00167463
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Differentiation of hepatocellular adenoma and focal nodular hyperplasia of the liver: comparison of power Doppler imaging and conventional color Doppler sonography (1997)
    Springer
    European radiology 7 (1997), S. 1410-1415 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Liver ; focal nodular hyperplasia ; Liver neoplasms ; diagnosis ; US ; Ultrasound ; Doppler studies ; power Doppler studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of our study was to compare the diagnostic efficacy of power Doppler imaging and conventional color Doppler sonography for differentiating between hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH) of the liver. Thirty-one focal liver lesions (in 29 patients) with histologic proof of HCA (n = 9) or FNH (n = 22) were studied with power and color Doppler sonography according to a standardized examination protocol. The size of the lesions ranged between 1.5 and 14.5 cm (HCA, 3.5–14.5 cm, mean ± SD 7.3 ± 3.3 cm; FNH, 1.5–9.1 cm, mean ± SD 5.1 ± 2.1 cm). Intratumoral vessels with a venous Doppler spectrum, associated with either pulsatile or continuous peripheral flow, were detected in HCA (eight of nine lesions by power Doppler imaging and six of nine by color Doppler imaging) but not in FNH. In contrast, color signals with an arterial Doppler spectrum, radiating from the center to the periphery of the lesion, were depicted in FNH (20 of 22 cases by power Doppler imaging and 15 of 22 by color Doppler sonography) but not in HCA. Differentiation of HCA and FNH was achieved in 28 of 31 cases (90 %) by power Doppler imaging and in 21 of 31 (68 %) by color Doppler sonography (p 〈 0.01). Power Doppler imaging is superior to conventional color Doppler sonography in the depiction of the intratumoral flow characteristics of HCA and FNH, and enables a more accurate differential diagnosis than color Doppler sonography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050308
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  • 4
    Electronic Resource
    Electronic Resource
    Radiological findings in a case of Menkes' disease (1995)
    Springer
    Child's nervous system 11 (1995), S. 112-114 
    Details
    ISSN: 1433-0350
    Keywords: Menkes' disease ; Copper deficiency ; Pili torti ; Magnetic resonance imaging ; Skeletal roentgenography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Menkes' disease, a neurodegenerative progressive X-linked disorder, was diagnosed in a 4-month-old child. The diagnosis was made on the combination of clinical features with laboratory and radiological findings. The pathogenesis of the skeletal findings in Menkes' disease is as yet unclear. Because of the severity of the prognosis and in order to plan treatment, the correct diagnosis has to be reached quickly. Typical manifestations of the syndrome are likely to develop after 3 months of age, with a pleiotropic appearance. In the present case, on the basis of the clinical investigation the patient underwent retrograde cystourethrography, roentgenographic examination of the skeleton, and magnetic resonance imaging of the brain. On analysis of the magnetic resonance imaging, we detected one-sided involvement of both subcortical and cortical parenchyma resembling a unilateral ischemic lesion such as, to our knowledge, has not yet been reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00303816
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    Paper (German National Licenses)
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