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  • Chemistry  (10)
  • Adrenoleukodystrophy  (2)
  • Glycogen phosphorylase kinase  (2)
  • Lung  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Phosphorylation of mylein basic protein by glycogen phosphorylase kinase
    Amsterdam : Elsevier
    FEBS Letters 169 (1984), S. 224-228 
    Details
    ISSN: 0014-5793
    Keywords: Glycogen phosphorylase kinase ; Mylein basic protein ; Rabbit skeletal muscle ; cAMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(84)80323-3
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of dextran solution on pulmonary plasma-lymph barrier in awake sheep
    Amsterdam : Elsevier
    Respiration Physiology 68 (1987), S. 239-250 
    Details
    ISSN: 0034-5687
    Keywords: Blood vessels ; Circulation ; Dextran ; Lung ; Lymph flow ; Oncotic pressure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0034-5687(87)80009-9
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Plasma levels of atrial natriuretic peptide under acute hypoxia in normal subjects
    Amsterdam : Elsevier
    Respiration Physiology 76 (1989), S. 79-91 
    Details
    ISSN: 0034-5687
    Keywords: ANP ; Hemodynamics ; Human ; Hypoxia ; Lung ; Pulmonary artery pressure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0034-5687(89)90019-4
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Two diverse effects of poly(L-lysine) on rabbit skeletal muscle phosphorylase kinase: stimulation of autophosphorylation and inhibition of its activity
    Amsterdam : Elsevier
    FEBS Letters 166 (1984), S. 335-338 
    Details
    ISSN: 0014-5793
    Keywords: Autophosphorylation ; Glycogen phosphorylase kinase ; Polylysine ; Rabbit skeletal muscle
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(84)80107-6
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Adrenoleukodystrophy: detection of increased very long chain fatty acids by high-performance liquid chromatography (1983)
    Springer
    Journal of neurology 230 (1983), S. 209-215 
    Details
    ISSN: 1432-1459
    Keywords: Adrenoleukodystrophy ; Adrenomyeloneuropathy ; Fatty acids ; High-performance liquid chromatography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mittels Hochleistungs-Flüssigkeitschromatographie wurden durch Analyse der Fettsäuren in Sphingomyelien Adrenoleukodystrophien und Adrenomyeloneuropathien untersucht. Die oben erwähnte analytische Methode erwies sich als einfach, empfindlich und exakt. Bei der Adrenoleukodystrophie und bei Patienten mit Adrenomyeloneuropathie wurden sehr lange Fettsäureketten (C26:0, C25:0 und C24:0 auf der Basis von C22:0) sowohl in Plasma und den Erythrozytenmembranen als auch in Gesamtblutproben als vermehrt erkannt. Auch in Kulturen von Hautfibroblasten von Sphingomyelien wurde eine Zunahme der langkettigen Fettsäuren nachgewiesen. In einem Fall eines heterozygoten Adrenoleukodystrophiepatienten wurden Werte die zwischen jenen der homozygoten und der Kontrollfälle lagen gefunden. Somit ist die Hochleistungs-Flüssigkeitschromatographie eine brauchbare Methode, um eine Zunahme langkettiger Fettsäuren zwecks Diagnose einer Adrenoleukodystrophie oder einer Adrenomyeloneuropathie festzustellen.
    Notes: Summary Using high-performance liquid chromatography, adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) were diagnosed by the analysis of fatty acids in sphingomyelin. The analytical method was simple, sensitive and accurate. In ALD and AMN patients, very long chain fatty acids (C26:0, C25:0 and C24:0 on the base of C22:0) were elevated not only in plasma and erythrocyte membranes but also in whole blood samples. An increase of long chain fatty acids was also shown in sphingomyelin of cultured skin fibroblasts. One heterozygote for ALD showed intermediate values between homozygotes and controls. Thus, high-performance liquid chromatography is a valuable method to detect increased long chain fatty acids for the diagnosis of ALD or AMN.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313696
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  • 6
    Electronic Resource
    Electronic Resource
    Adrenoleukodystrophy and beta-galactosidase deficiency: Patient and carrier (1986)
    Springer
    Journal of neurology 233 (1986), S. 306-308 
    Details
    ISSN: 1432-1459
    Keywords: Adrenoleukodystrophy ; Beta-galactosidase deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A patient with adrenoleukodystrophy and his mother, a carrier, showed an elevated ratio of very long-chain fatty acids to long-chain fatty acids and decreased beta-galactosidase activity. Other lysosomal enzyme activities were normal except for the borderline level of arylsulfatase-A activity. However, the father and other patients with variant forms of adrenoleukodystrophy showed normal beta-galactosidase and other lysosomal enzyme activities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314164
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  • 7
    Electronic Resource
    Electronic Resource
    On-line combination of supercritical-fluid chromatography with fast-atom bombardment mass spectrometry (1990)
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 4 (1990), S. 381-383 
    Details
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Studies on combined supercritical-fluid chromatography (SFC) using a packed column, with fast-atom bombardment mass spectrometry (FAB-MS) are described. The interfacing was successfully carried out by simply coupling a frit interface between the liquid chromatograph (LC) and the mass spectrometer. The interface was equipped with a pneumatic splitter and post-column addition device delivering FAB matrix material to a release valve which maintained a constant back-pressure at the column outlet. Using a 1% glycerol solution as a matrix compound in the release valve, the SFC/FAB-MS combination operates as well as a normal LC/MS instrument. The performance was demonstrated with a mixture of α-, β- and γ-tocopherol and Triton X-100 (poly(ethylene glycol) p-isooctylphenyl ether).
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/rcm.1290041007
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  • 8
    Electronic Resource
    Electronic Resource
    Fracture studies in rubber-modified acrylics. I. Experimental method: Design of sandwich-tapered double-cantilever beam cleavage specimens (1973)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 17 (1973), S. 1909-1917 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Double-cantilever beam cleavage specimens are very useful in characterizing the fracture behavior of isotropic, homogeneous, brittle, and semibrittle polymers. However, until this time they have not been used for ductile materials such as rubber-modified polymers or polycarbonates because of excessive yielding or breakage of the specimen arms before crack propagation can occur. In order to make it possible to measure the fracture surface work of these materials, a new sandwich cleavage specimen was developed by bonding rigid reinforcement plates to both sides of the specimen sheet. With this sandwich-tapered double-cantilever beam cleavage specimen, one can create conditions under which controlled crack propagation through tough ductile materials and measurement of the fracture surface work-two previously unobtainable results-are readily determined. In this paper, the design and construction of the sandwich specimens, test procedure, and the data analysis will be discussed in detail.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1973.070170623
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  • 9
    Electronic Resource
    Electronic Resource
    Fracture studies in rubber-modified polymers. II. Experimental results: Fracture surface work of rubber-modified acrylics (1973)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 17 (1973), S. 2053-2066 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: With the use of a sandwich-tapered double-cantilever beam cleavage specimen (described in part I of this series), the fracture surface work of several commercial and experimental acrylic multipolymers has been measured as a function of crack velocity and rubber content. The plots of fracture surface work versus crack velocity clearly exhibit the effects of rate (crack velocity) and rubber concentration on fracture behavior. Specifically, the fracture surface work of specimens with seven different rubber contents has been determined over a crack velocity range from 10-5 meters/sec to approximately 10 meters/sec. For each material, distinct maxima occur in the curves of fracture surface work versus crack velocity. The significance of these observations is discussed.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1973.070170708
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  • 10
    Electronic Resource
    Electronic Resource
    Fourier transform infrared spectroscopic analysis of rat brain microsomal membranes modified by dietary fatty acids: Possible correlation with altered learning behavior (1997)
    New York, NY [u.a.] : Wiley-Blackwell
    Biospectroscopy 3 (1997), S. 281-290 
    Details
    ISSN: 1075-4261
    Keywords: brain microsomal membranes ; fatty acids ; learning behavior ; FTIR ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: We measured the Fourier transform infrared spectra of brain microsomal membranes prepared from rats fed under two dietary oil conditions with and without brightness-discrimination learning tasks: one group fed α-linolenate deficient oil (safflower oil) and the other group fed the sufficient oil (perilla oil) from mothers to offspring. The infrared spectra of microsomes under the two dietary conditions without the learning task showed no significant difference in the range 1000-3000 cm-1. Only after the learning task were the infrared spectral differences noted between the microsomal membranes from both groups. Spectral differences were observed mainly in the absorption bands of fatty acid ester at around 1730 cm-1 (sn-2 position), those of phosphate and oligosaccharides in the range of 1050-1100 cm-1, and a band at around 1145 cm-1. The infrared band of fatty acid ester at the sn-2 position in the microsomal membrane shifted to a longer wavenumber position in the perilla oil group than in the safflower oil group, suggesting a difference between both groups in hydrogen bonding of the fatty acid ester with water. A band observed at 1055 cm-1 and a small band at around 1145 cm-1 in the second derivative spectrum decreased in intensity in the perilla oil group after learning task. These bands were assigned mainly to the oligosaccharide C - O bond in hydroxyl groups that might interact with some other membrane components. These results suggest changes in hydration of membrane surface and modification in oligosaccharide environment (removal or modification) of microsomes, which may be correlated in part with dietary oil-induced changes in learning performance. © 1997 John Wiley & Sons, Inc. Biospectroscopy 3: 281-290, 1997
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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