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  • Analytical Chemistry and Spectroscopy  (5)
  • Aging  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Polyglucosan bodies in the digestive tract of the aged dog (1983)
    Springer
    Acta neuropathologica 60 (1983), S. 297-300 
    Details
    ISSN: 1432-0533
    Keywords: Polyglucosan bodies ; Lafora-like bodies ; Aging ; Smooth muscles ; Digestive tract ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In our recent studies on aging phenomena in animals, polyglucosan bodies (PGB) were found within the smooth muscle in the digestive tract of aged dogs without neurologic signs. PGB were basophilic, round, or oval bodies which appeared to have a homogenous or concentric shape. Their histochemical properties were characterized by the presence of glucose polymers (polyglucosan). Electron microscopy revealed that PGB were composed mainly of irregularly clustered, short branching filaments measuring about 90 Å in width. PGB were histochemically and ultrastructurally identical to the previously reported Lafora-like bodies in the CNS of aged dogs. PGB were found in all aged dogs and were disseminated throughout the digestive tract, especially in the cecum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691880
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs (1979)
    Springer
    Acta neuropathologica 48 (1979), S. 77-81 
    Details
    ISSN: 1432-0533
    Keywords: Aging ; Nucleus gracilis ; Conus medullaris ; Intra-spheroidal Lafora-like bodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The gracile nucleus and conus medullaris, the sites of predilection for spheroids and Lafora-like bodies, were examined light and electron microscopically in 91 dogs ranging from 1 month to 19 years of age. The number of both structures showed a tendency to increase with age. Spheroids have already been found in younger dogs before the appearance of Lafora-like bodies. In the aged dog, intra-spheroidal Lafora-like bodies were occasionally observed. Correlative studies may yield clues on the pathogenesis of aging phenomena in the CNS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691796
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Lafora-like inclusion bodies in the CNS of aged dogs (1978)
    Springer
    Acta neuropathologica 44 (1978), S. 217-222 
    Details
    ISSN: 1432-0533
    Keywords: Lafora-like inclusion bodies ; Aging ; Dog ; High incidence ; Comparative neuropathology ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty randomly selected dogs, arranged into three groups according to age, were examined light and electron microscopically. Lafora-like inclusion bodies were found in all cases of aged dogs without neurological signs. They appeared as PAS positive, round bodies measuring up to 15μm in diameter. Typically they had central cores and radiating peripheral lines. Electronmicroscopically, the inclusions consisted of irregularly clustered, short branching filaments measuring about 80–120 Å in diameter or of electrondense homogeneous or granular central cores with filamentous peripheral areas and located both in the perikarya and neuronal processes. The inclusions were disseminated all over the brain and spinal cord. The thalamic nuclei, a circumscribed area dorsal to the aqueduct, and the molecular layer of the superior colliculus were the most severely affected. The frequency of the inclusions showed age-dependency; the inclusions were not found in dogs younger than 2 years, but were extensive in all dogs of more than 8 years of age. The occurrence of the inclusions may therefore represent an age-dependent phenomenon. The relationship between the present findings and Lafora's disease is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691070
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Simultaneous analysis for acid phosphatase and alkaline phosphatase by ion-exchange liquid chromatography (1987)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 10 (1987), S. 108-109 
    Details
    ISSN: 0935-6304
    Keywords: Ion-exchange liquid chromatography ; Acid phosphatase ; Alkaline phosphatase ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240100215
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Micro high performance liquid chromatography of aliphatic amines by means of resonance raman detection (1987)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 10 (1987), S. 173-176 
    Details
    ISSN: 0935-6304
    Keywords: Micro high performance liquid chromatography, micro-HPLC ; Resonance Raman detection ; Dabsylamide ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A micro high performance liquid chromatography coupled with a resonance Raman detection system is described. For highly sensitive Raman detection, aliphatic amines were derivatized with dabsyl chloride (4-dimethylaminoazobenzene-4′-sulfonyl chloride). The derivatives were separated on an ODS micro column (0.5 mm i.d. × 145 mm PTFE tube). Chromatograms were obtained by measuring the intensity of Raman scattering at 1136 cm-1 with the 488.0 nm line of an Arion laser. The lower detection limit was 1.5 ng and the RSD of relative peak height (n = 9) was 5.9% at 11 ng of methylamine derivative. Moreover, by stopping the flow of the micro HPLC system at the retention time of the individual derivatives, it was possible to measure their resonance Raman spectra.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240100403
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Multiple urinary isoenzyme assay by high-performance liquid chromatography (1986)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 9 (1986), S. 479-480 
    Details
    ISSN: 0935-6304
    Keywords: High-performance liquid chromatography, HPLC ; Alkaline phosphatase, AP ; Lactate dehydrogenase, LD ; γ-Glutamyltransferase ; γ-GT ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240090817
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    The effect of oxidation state on the intensities of Kβ5 and Kβ″ of 3d-transition elements (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    X-Ray Spectrometry 4 (1975), S. 186-189 
    Details
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Using a commercially available flat crystal spectrometer in a slightly modified form, an investigation was made of the peak intensity ratios (Kβ5/Kβ1) and the relative intensities of Kβ″ to Kβ5 in different oxidation states of 3d-transition metal atoms existing in forms of oxidic compounds. The peak intensity ratios (Kβ5/Kβ1) for V, Cr, Mn, Fe, Co, Ni and Cu, as well as the peak profiles of Kβ″ and Kβ5 for V, Cr and Mn, were investigated. Results suggest that changes in the intensities of the Kβ5 and Kβ″ bands can be applied to determining the oxidation number of a metal atom in its oxide.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/xrs.1300040408
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Enhanced Raman scattering from silver metal gratings coated with p-nitrobenzoic acid films (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 25 (1994), S. 303-306 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The Raman scattering from echelette silver gratings coated with p-nitrobenzoic acid (PNBA) films was measured as a function of the angle of incidence of the exciting laser beam. It was found that on excitation of surface plasmon polaritons (SPPs) on the grating, the Raman scattering intensity of the adsorbed PNBA- species is enhanced by a factor of five compared with its intensity at off-resonance angles of incidence. However, an enhancement of about a factor of 10 in our estimation is observed with s-polarized radiation independent of the angle of incidence, indicating the presence of some supplementary mechanism other than the high-field intensity of SPP in the enhancement process. No Raman bands due to PNBA were observed in the thickness range up to 50 nm.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250250502
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    Paper (German National Licenses)
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