Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Actinic elastosis in black skin (1978)
    Springer
    Archives of dermatological research 262 (1978), S. 7-14 
    Details
    ISSN: 1432-069X
    Keywords: Black skin ; Actinic elastosis ; Light- and electronmicroscopy ; Fibroblastic product ; Negerhaut ; Aktinische Elastose ; Licht- und Elektronenmikroskopie ; Fibroblastenprodukt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 9 hautgesunden südafrikanischen schwarzen Freiwilligen im Alter von 1–72 Jahren wurde sonnenlichtexponierte und nichtexponierte Haut licht- und elektronenmikroskopisch untersucht unter besonderer Berücksichtigung altersabhängiger und aktinisch bedingter Veränderungen dermaler Strukturen. Während bei einer 72jährigen Frau eine ausgeprägte aktinische Elastose im oberen Corium der sonnenexponierten Haut licht- und elektronenoptisch nachweisbar war, fand sich bei einem 72jährigen Mann eine nur elektronenoptisch darstellbare geringe Elastose. Im Gegensatz dazu waren bei diesen beiden Fällen im unteren Corium der sonnenexponierten und in allen Schichten der nichtexponierten Haut nur altersentsprechende elastische Fasern vorhanden. Diese Beobachtungen stehen in Gegensatz zu der noch gängigen Auffassung, daß eine aktinische Elastose bei der kongoiden Rasse nicht auftritt. Das elastotische Material ist offensichtlich ein de-novo-synthetisiertes und sezerniertes pathologisches Produkt von (durch chronische UV-Bestrahlung) alterierten Fibroblasten.
    Notes: Summary In 9 otherwise dermatologically normal South African Black volunteers (1–72 years old), sunlight-exposed and non-exposed skin has been examined by light- and electronmicroscopy with special references to age-dependent and actinic alteration of dermal structures. Two 72 year old Blacks exhibited typical dermal elastosis: in 1 case to a marked extent and already detectable by lightmicroscopy, in the other case only to a mild degree. In contrast, only age-related elastic fibers were revealed in the lower dermis of sunlight-exposed skin and in all dermal layers of unexposed skin. These observations are contradictory to the general view that actinic elastosis does not occur in Blacks. The elastotic material is obviously a de-novo synthesized and secreted pathological product of chronically UV-altered fibroblasts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00455568
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Increase in types IV and VI collagen in cherry haemangiomas (1992)
    Springer
    Archives of dermatological research 284 (1992), S. 275-282 
    Details
    ISSN: 1432-069X
    Keywords: Cherry haemangioma ; Type IV collagen ; Type VI collagen ; Immunohistochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The capillaries in cherry haemangiomas show perivascular hyalinized sheaths. In order to clarify the nature of this sheath material, the extracellular matrix of cherry haemangiomas from 20 normal volunteers (age range 30–64 years) was investigated using immunohistochemical and electronmicroscopical methods. Antibodies against collagen types III, IV and VI and laminin were used. Hyaluronic acid was visualized using the hyaluronic acid binding region of the cartilage proteoglycan as ligand. Electronmicroscopically, the sheaths contained multilaminated basement membrane-like material, collagen fibres 20–25 nm thick with a periodicity of 67 nm and broad-banded aggregates with a periodicity of 100 nm (zebra bodies or fibrous long-spacing fibres). Immunohistochemically, type IV collagen was stained throughout the whole sheath material. Staining for laminin was more confined to the endothelial side of the sheath. Intense staining for type III collagen and hyaluronic acid was found in the connective tissue of the subpapillary layer and between the cherry haemangioma capillaries. Much weaker staining for type III collagen and no staining for hyaluronic acid were found invariably in an area 4–10 Μm thick directly around the capillaries. Both sheath material and intercapillary connective tissue of the haemangiomas showed pronounced staining for collagen type VI. Immunogold staining revealed that type VI collagen was localized to microfibrils 5–6 nm thick and to the broad-banded aggregates with 100 nm periodicity. These findings further underline the assumption that the broad-banded aggregates consist of type VI collagen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00372581
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...