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  • General Chemistry  (3)
  • Allenes  (1)
  • CD40  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Baboon T cell lymphomas expressing the B cell-associated surface proteins CD40 and Bgp95 (1992)
    Springer
    Journal of clinical immunology 12 (1992), S. 225-236 
    Details
    ISSN: 1573-2592
    Keywords: Non-Hodgkins malignant lymphoma ; human T cell leukemia virus-1 (HTLV-1) ; CD40 ; Bgp95 ; T cell ; baboon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Papio hamadryas baboons in the Sukhumi colony develop enzootic outbreaks of malignant lymphomas with an incidence of about 1.5% per year among adults of the high-risk stock. We investigated the surface phenotypes of cells from normal and lymphomatous animals using antibodies against human lymphocyte antigens. We found that more than 80% of the lymphomas that developed during the last 3 years were characterized histologically to be of the peripheral T cell type. Generally, the lymphomatous cells also expressed high levels of MHC class II DR protein, CD18 (LFA-1 beta chain), and CD45RO. Surprisingly, these cells also expressed on their surface two proteins previously characterized as being relatively B cell-restricted: CD40 and Bgp95. These proteins were never found on the peripheral blood T cells from normal animals. The expression of these two gene products was confirmed by RNA blotting and immunoprecipitation. In most cases, the two B cell-associated proteins were expressed on the predominant T cell subsets; we found both B cell proteins on CD4+, CD8+ as well as on the CD4/8 double-positive cells when these subsets were expressed at high levels. About 90% of these animals are seropositive forHerpesvirus papio and human T cell leukemia virus-1 (HTLV-1) before developing outright lymphomas. In all of the lymphoma samples, HTLV-1 tax DNA sequences were detected by PCR amplification. Whether or not HTLV-1 or theHerpesvirus papio gene products influence the surface expression of CD40 and Bgp95 remains to be determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00918093
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    [Hg7As4I3](SnI3): Trapping the SnI31- Anion in the Cavities of the Unprecedented Mercury-Arsenic-Iodine Network (2000)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 2000 (2000), S. 265-270 
    Details
    ISSN: 1434-1948
    Keywords: Host-guest compounds ; Tin ; Mercury ; Pnictide halides ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A novel host-guest compound [Hg7As4I3](SnI3) has been prepared by a standard ampoule technique and its crystal structure was determined. It crystallizes in a cubic system [space group P213, a = 13.110(1) Å, Z = 4] with a unique structure type. The crystal structure comprises two parts: the three-dimensional [Hg7As4I3]1+ host network, and the SnI31- guest anions encapsulated in the cavities of the network. The network is built from the As2Hg7 bitetrahedra and As2Hg6 octahedra, which share corners, and contains an additional iodine atom connected to one of the mercury vertices. The SnI31- anion has the shape of a pyramid with the tin atom in a vertex. According to the quantum-chemistry calculations, the geometry of the anion deviates substantially from the equilibrium one, and is influenced by the distant mercury atoms of the host network.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 3
    Electronic Resource
    Electronic Resource
    A Versatile Synthetic Method for Preparing 1,2,3,5-Tetrasubstituted Pyrroles Using Isothiocyanates and 2-Alkynyl Ethers or 2-Alkynylamines as Building Units (1999)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1999 (1999), S. 2663-2664 
    Details
    ISSN: 1434-193X
    Keywords: Metallations ; Copper ; Homogeneous catalysis ; Cyclizations ; Regioselectivity ; Azatrienes ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A fundamentally new approach for the construction of pyrrole rings is exemplified by highly efficient one-pot syntheses of 1,2,3,5-tetrasubstituted pyrroles starting from alkyl isothiocyanates and 2-alkynylamines or 2-alkynyl ethers.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 4
    Electronic Resource
    Electronic Resource
    One-Pot Syntheses of 2-N-Alkylamino-, 2-N-Phenylamino-, 2-N, N-Dialkylamino-, and 2-N-Alkyl-N-phenylaminothiophenes (1998)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1998 (1998), S. 253-256 
    Details
    ISSN: 1434-193X
    Keywords: Isothiocyanates ; Acetylenes ; Allenes ; Cyclization ; Thiophenes ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A number of 2-N-alkylamino- or 2-N-phenylamino-, 2-N, N-dialkylamino-, and 2-N-alkyl-N-phenylaminothiophenes have been prepared in good yields by adding a solution of tert-butylalcohol and potassium tert-butoxide in dimethylsulfoxide to a solution of the adduct from a lithiated 1-alkyne, RCH2C≡CLi, or the lithiated allene, tBuCH=C=CHLi, and isothiocyanate, R′N=C=S, in tetrahydrofuran and subsequently hydrolyzing the reaction mixture or quenching it with methyl iodide.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
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