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  • Tuberculosis  (4)
  • Analytical Chemistry and Spectroscopy  (3)
  • Blasting  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 36 (1994), S. 39-43 
    ISSN: 1432-1920
    Keywords: Spine ; Spinal cord ; Tuberculosis ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied 20 patients with intraspinal tuberculosis (TB), to characterise the MRI features of tuberculous meningitis and myelitis. MRI leptomeningitis and intramedullary involvement in 11 patients, intramedullary lesions alone in 5, leptomeningitis alone in 2, and isolated extradural disease in 2. TB leptomeningitis was characterised by loculation of the cerebrospinal fluid (CSF), nerve root thickening and clumping (seen only in the lumbar region) or complete obliteration of the subarachnoid space on unenhanced images. Gd-DTPA-enhanced images proved useful in 6 cases, revealing linear enhancement of the surface of the spinal cord and nerve roots or plaque-like enhancement of the dura-arachnoid mater complex. Intramedullary lesions included tuberculomas (8), cord oedema (5) and cavitation (3). In seven cases of intramedullary tuberculoma multiple lesions with skip areas were seen, without significant cord swelling. One patient had an isolated lesion in the conus medullaris. The lesions were iso- or hypointense on T1-weighted images, iso-, hypo- or hyperintense on T2-weighted images and showed rim or nodular enhancement with contrast medium.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1920
    Keywords: Key words Spine ; infections ; Spine ; neoplasms ; Tuberculosis ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reviewed MRI studies of 60 patients presenting with extradural compressive myeloradiculopathy secondary to vertebral disease to assess the imaging features which may help in differentiating tuberculous from neoplastic disease. Spin-echo T1-, proton density- and T2-weighted images were available for all patients and fast low-angle shot images with a low flip angle for 21 patients. Contrast-enhanced images were available for 28 patients. There were 41 patients with tuberculosis and 19 patients with neoplastic disease (metastases 11, lymphoma 6, plasmacytoma 1, and giant cell tumour 1). Discovertebral disease with or without involvement of the posterior arch was a feature not only of tuberculous spondylitis (30 patients) but also of metastases (6). The remaining 11 patients with tuberculosis had “atypical” involvement (vertebral body with or without posterior arch in 8 and posterior arch alone in 3) described as typical of neoplasms. This “typical” involvement was seen in metastases (5), lymphoma (6) and the 2 primary bone tumours. The presence of an abscess helped in differentiating tuberculosis from neoplasia in 22 of the 41 patients with tuberculosis and was absent in all with neoplasms. The presence of bone fragments in 16 patients (8 with and 8 without an abscess) was found to be specific for tuberculosis. In the absence of an abscess or bone fragments, image-guided biopsy is essential to establish the diagnosis.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Spine, infections ; Spine, neoplasms ; Tuberculosis ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reviewed MRI studies of 60 patients presenting with extradural compressive myeloradiculopathy secondary to vertebral disease to assess the imaging features which may help in differentiating tuberculous from neoplastic disease. Spinecho T1-, proton density- and T2-weighted images were available for all patients and fast low-angle shot images with a low flip angle for 21 patients. Contrast-enhanced images were available for 28 patients. There were 41 patients with tuberculosis and 19 patients with neoplastic disease (metastases 11, lymphoma 6, plasmacytoma 1, and giant cell tumour 1). Discovertebral disease with or without involvement of the posterior arch was a feature not only of tuberculous spondylitis (30 patients) but also of metastases (6). The remaining 11 patients with tuberculosis had “atypical” involvement (vertebral body with or without posterior arch in 8 and posterior arch alone in 3) described as typical of neoplasms. This “atypical” involvement was seen in metastases (5), lymphoma (6) and the 2 primary bone tumours. The presence of an abscess helped in differentiating tuberculosis from neoplasia in 22 of the 41 patients with tuberculosis and was absent in all with neoplasms. The presence of bone fragments in 16 patients (8 with and 8 without an abscess) was found to be specific for tuberculosis. In the absence of an abscess or bone fragments, image-guided biopsy is essential to establish the diagnosis.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Key words Magnetic resonance imaging ; Brain ; tuberculoma ; Tuberculosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract MRI was performed on patients with miliary pulmonary tuberculosis to look for brain involvement and to study the features sequentially, during treatment. We studied seven patients with typical radiographic tuberculosis, and no symptoms or signs of central nervous system involvement. Conventional spin-echo (SE) imaging, including contrast enhanced images, was performed in all cases. All patients showed brain involvement: four patients showed lesions mainly less than 3 mm in diameter, better seen on contrast-enhanced images. These patients showed oedema around the lesions after 2 months of treatment, with subsequent regression on follow-up. The remaining three patients had multiple lesions, 3 mm or more in diameter, which showed a gradual decrease on follow-up. We conclude that the brain may commonly be involved in miliary pulmonary tuberculosis. The response to treatment depends on the stage of the granuloma and shows a definite pattern of healing on follow-up.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Geotechnical and geological engineering 7 (1989), S. 301-313 
    ISSN: 1573-1529
    Keywords: Blasting ; cast blasting ; dam construction ; caving blast
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Summary A proposal is under consideration to construct a dam on an experimental basis by a cast (or directional) blasting technique, ‘DBT’. The dam site is located at Bharari Khad, a tributary of the Sutlaz river in Himachal Pradesh. Site investigations have been completed and a large scale blast has been designed for construction of the experimental dam. The paper describes the basic design concept of DBT and application of ‘throw’ and ‘caving’ methods for construction of dams. The preliminary tests required to design the blasting pattern are detailed. The technique has a great potential because it reduces construction cost and time particularly in inaccessible mountain regions.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Geotechnical and geological engineering 7 (1989), S. 239-248 
    ISSN: 1573-1529
    Keywords: Blasting ; rock fragmentation ; rock discontinuities ; surface mining ; quarrying
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Geotechnical and geological engineering 7 (1989), S. 333-340 
    ISSN: 1573-1529
    Keywords: Blasting ; fragmentation ; natural blocks ; surface mining ; quarrying
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 3 (1980), S. 419-420 
    ISSN: 0935-6304
    Keywords: Meprobamate ; Overdose toxicology ; Plasma monitoring ; Gas chromatography ; High-pressure liquid chromatography ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0749-1581
    Keywords: 1H NMR ; 13C NMR monomethyl/dimethyl 5α-androstan-3-ones ; Steroid ; Ring A conformation ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Ring A proton shifts and couplings and 13C shifts of all carbons are given for 17β-acetoxy-2α-methyl- and 17β-methoxy-2β-methyl-5α-androstan-3-one and 2,2-dimethyl-17β-methoxy-5α-androstan-3-one. It was concluded that the 2β-methyl derivative exists with ring A in a regular chair conformation while the 2β-methyl derivative exists with ring A in an inverted boat conformation with C-2 and C-5 at the bow/stern positions. The data for 2,2-dimethyl-17β-methoxy-5α-androstan-3-one suggest an equilibrium of these two conformers.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0749-1581
    Keywords: steroids ; 1H NMR ; 13C NMR ; coupling constants ; conformational analysis ; 1D TOCSY ; NOE ; cyclosteroids ; cyclopropanosteroids ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Proton and carbon NMR data are provided for 21 ring A and ring B cyclosteroids and cyclopropano (or methylene) steroids. Shift assignments were made using standard 2D NMR techniques, while ring A proton subspectra were extracted with a 1D TOCSY experiment. Coupling constants were obtained from iterative spin system simulation of these sub-spectra. Ring A conformations were determined from the two- and three-bond proton-proton couplings and NOE measurements. The utility and limitations of extended Karplus-type equations, the effect of cyclopropyl groups on vicinal and geminal couplings and cyclopropane-induced chemical shifts are discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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