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  • Analytical Chemistry and Spectroscopy  (2)
  • Chemical Engineering  (2)
  • Down's syndrome  (2)
  • Drosophila melanogaster  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Evidence for multiple forms of the prothoracicotropic hormone in Drosophila melanogaster and indication of a new function
    Amsterdam : Elsevier
    Journal of Insect Physiology 38 (1992), S. 167-173+175-176 
    Details
    ISSN: 0022-1910
    Keywords: Drosophila melanogaster ; Prothoracicotropic hormone ; ecdysone synthesis ; heat-shock protein
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0022-1910(92)90065-L
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  • 2
    Electronic Resource
    Electronic Resource
    Presence of non-fibrillar amyloid b protein in skin biopsies of Alzheimer's disease (AD), Down's syndrome and non-AD normal persons (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 201-206 
    Details
    ISSN: 1432-0533
    Keywords: Key words Amyloid β protein ; Skin biopsy ; Alzheimer's disease ; Down's syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 66 skin biopsies from persons with Alzheimer's disease (AD) or Down's syndrome (DS) and from persons without AD were used in this study. The age range was from 7 to 89 years. Positive immunoreactivity of skin biopsies to monoclonal antibody 4G8, which is reactive to amino acid residue 17 – 24 of synthetic amyloid β protein (Aβ), and 4G8-Fab (the antigen-binding fragment of 4G8 IgG, reactive only to amyloid plaque) was observed in the epidermis-dermis junction or the basement membrane of the epidermis and in some blood vessels of the biopsy skins of 13/18 (72  %) AD, 9/10 (90  %) DS, and 14/38 (37  %) non-AD control cases. The Fisher exact probability test revealed a significant difference (P=0.0415 one-tailed) in immunoreactivity between AD and age-matched controls. There was also a significant difference (P=0.0152 one-tailed; P=0.0200 two-tailed) between DS and age-matched control in the same test. Immuno-gold electron microscopy examination of these cases with positive immunoreactivity revealed that the gold particles were deposited along the basement membrane of the epidermis. Amyloid fibrils were not observed in the regions with gold particles. Results of this study suggest that Aβ is associated with the basement membrane of skin and is present in amorphous, non-fibrillar form as soluble Aβ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293394
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Presence of non-fibrillar amyloid β protein in skin biopsies of Alzheimer's disease (AD), Down's syndrome and non-AD normal persons (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 201-206 
    Details
    ISSN: 1432-0533
    Keywords: Amyloid β protein ; Skin biopsy Alzheimer's disease ; Down's syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 66 skin biopsies from persons with Alzheimer's disease (AD) or Down's syndrome (DS) and from persons without AD were used in this study. The age range was from 7 to 89 years. Positive immunoreactivity of skin biopsies to monoclonal antibody 4G8, which is reactive to amino acid residue 17–24 of synthetic amyloid β protein (Aβ), and 4G8-Fab (the antigen-binding fragment of 4G8 IgG, reactive only to amyloid plaque) was observed in the epidermis-dermis junction or the basement membrane of the epidermis and in some blood vessels of the biopsy skins of 13/18 (72%) AD, 9/10 (90%) DS, and 14/38 (37%) non-AD control cases. The Fisher exact probability test revealed a significant difference (P=0.0415 one-tailed) in immunoreactivity between AD and age-matched controls. There was also a significant difference (P=0.0152 one-tailed; P=0.0200 two-tailed) between DS and age-matched control in the same test. Immuno-gold electron microscopy examination of these cases with positive immunoreactivity revealed that the gold particles were deposited along the basement membrane of the epidermis. Amyloid fibrils were not observed in the regions with gold particles. Results of this study suggest that Aβ is associated with the basement membrane of skin and is present in amorphous, non-fibrillar form as soluble Aβ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293394
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Identification of ovarian enhancer-binding factors which bind to ovarian enhancer 1 of theDrosophila genesyp1 andyp2 (1996)
    Springer
    Molecular genetics and genomics 251 (1996), S. 347-351 
    Details
    ISSN: 1617-4623
    Keywords: Yolk protein ; Ovarian enhancer 1 ; Enhancer-binding factors ; Drosophila melanogaster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract It has been reported that three different DNA regions — the fat body enhancer and ovarian enhancers 1 and 2 — direct the tissue-specific expression ofyp1 andyp2 inDrosophila melanogaster. In the present study, we identified ovarian enhancer 1-specific binding proteins. Electrophoretic mobility shift assay revealed that these proteins are present in the adult ovary, but not in adult testis or fat body. Southwestern blot analysis showed that about 130 kDa and 40 kDa proteins, designated OEF1 and OEF2, respectively, from ovarian nuclear or crude extracts bind specifically to the ovarian enhancer 1. The two proteins were partially purified by streptavidin/agarose-DNA affinity chromatography, and their binding activity was confirmed by electrophoretic mobility shift assay. These ovarian enhancer factors may play an important role in the regulation of transcription ofyp1 andyp2 in the ovary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02172525
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  • 5
    Electronic Resource
    Electronic Resource
    Capillary end-sealing for static coating (1982)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 5 (1982), S. 571-571 
    Details
    ISSN: 0935-6304
    Keywords: Capillary, Glass, Nylon, Teflon, Fused silica ; Static coating ; Sealing, In-place solidification ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240051013
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Gas chromatography of volatile fatty acids as tert-butyidimethylsilyl esters (1987)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 10 (1987), S. 522-523 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography ; Volatile fatty acids ; tert-Butyldimethylsilyl esters ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240100910
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  • 7
    Electronic Resource
    Electronic Resource
    Drop-size distributions from pneumatic atomizers (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 575-584 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A study was made of the atomizing characteristics of convergent-type pneumatic nozzles. Drop-size correlations were obtained for the following ranges: drop size, 6 to 350 μ, mass median diameter; mass flow ratio, 0.06 to 40; relative velocity, 250 ft./sec. to sonic velocity; and viscosity. 1 to 50 cp. The technique employed was to spray cool a molten wax, and melts of wax-polyethylene mixtures. The most important operating variables in pneumatic atomization are the dynamic force of the atomizing gas, and the mass flow ratio of air to liquid. The cumulative volume drop-size distribution of spray from a pneumatic nozzle was fitted by a modified logistic equation. Empirical correlations developed in the study can be used to design nozzles or to predict drop size for sprays produced by the types of nozzles studied. In particular, this study provides new experimental data on the performance of pneumatic atomizers in producing relatively large drops.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170318
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  • 8
    Electronic Resource
    Electronic Resource
    Diffusion in nickel oxide pellets-effects of sintering and reduction (1974)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 20 (1974), S. 670-678 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Diffusion rates were measured at 25°C and 1 atm by a steady state method in pellets of nonporous nickel oxide particles in order to determine the effects of sintering and chemical reduction. Sintering led to a striking decrease in diffusion flux; tortuosities above 100 were found for highly sintered (porosity 0.03) pellets. Reduction caused a sharp increase in diffusion rate when the original pellet was highly sintered. For an originally unsintered pellet the diffusion rate decreased with extent of reduction.These phenomena were explained quantitatively by using: (1) the random pore model to predict tortuosity factors for an unsintered, unreduced pellet, and (2) the extent of pore interconnections and the fractional reduction to treat the effects of sintering and reduction. In this way an approximate, predictive equation was derived which contained no arbitrary parameters and which required for application only data on porosity and extent of chemical reduction.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690200407
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