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  • 1
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Lungenrundherde ; Amyloidose ; Bronchialcarcinom ; Computertomographie ; Lungenbiopsie ; Key words Lung nodule ; Amyloidosis ; Bronchial carcinoma ; Computed tomography ; Lung biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report a rare case of pulmonary nodular amyloidosis featuring all typical morphologic alterations associated with this disease; multiple amyloidomas, calcification and cavernous transformation were present. Definite diagnosis was established histologically with CT-guided biopsy. The different types of pulmonary amyloidosis and their radiological appearances are described and discussed.
    Notes: Zusammenfassung Wir berichten über einen seltenen Fall einer pulmonalen nodulären Amyloidose mit allen typischen Merkmalen dieser Erkrankung bei gleichzeitigem Vorliegen von multiplen Amyloidomen mit Verkalkungen und zentralen Einschmelzungen. Die definitive Diagnose wurde histologisch mit einer CT-gesteuerten Biopsie gesichert. Die verschiedenen Formen der pulmonalen Amyloidose und deren radiologische Erscheinungsbilder werden beschrieben und diskutiert.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 356 (1982), S. 141-149 
    ISSN: 1435-2451
    Keywords: Acute pancreatitis ; Computed tomography ; Ultrasound ; Operative treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die „stadiengerechte Therapie” der akuten Pankreatitis, die jedem Schweregrad der Erkrankung angemessen ist, besteht neben der konservativen Basistherapie und Intensivmedizin im richtigen Einsatz operativer Maßnahmen. Voraussetzung dafür ist die frühe Diagnose und Beurteilung des Schweregrades der akuten Pankreatitis. Neben klinischen und klinisch-chemischen Befunden und dem Verlauf unter konservativer Therapie ermöglichen die Sonographie und die Computer-Tomographie eine bessere Beurteilung der jeweiligen Verlaufsform. Die für die Klinik der Erkrankung so wichtigen morphologischen Veränderungen der Bauchspeicheldrüse und ihrer Umgebung werden durch diese neuartigen Untersuchungsmethoden transparenter. Wäh rend bei der leichten Pankreatitis die Sonographie als erstes morphologisches Untersuchungsverfahren eingesetzt wird, besteht bei den schweren Verlaufsformen eine klassische Indikation zur Computer-Tomographie. Durch Einsatz von Sonographie und Computer-Tomographie läßt sich die Indikation zur frühzeitigen oder verzögerten Operation der hämorrhagisch-nekrotisierenden Pankreatitis, die bisher nach klinischen Kriterien erfolgte, in den meisten Fällen exakter stellen.
    Notes: Summary Adequate stage-depending therapy of acute pancreatitis includes basic conservative treatment, intensive care measurements, and operative interventions depending on the grade of severity. Prerequisites are early diagnosis and accurate clinical assessment of the stage of severity. Beside clinical and laboratory findings, as well as the development of acute pancreatitis under conservative treatment, sonography and computed tomography allow a better prediction of the underlying morphological changes, thus leading to an exact staging of the patient's individual situation. Sonography is regarded a screening procedure of high accuracy in mild forms of acute pancreatitis. Computed tomography is the method of choice in all severe forms of this disease. The indication for immediate or delayed operative treatment of hemorrhagic necrotising pancreatitis, heretofore depending on clinical findings solely, is supported by these new-invasive diagnostic modalities.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 802-802 
    ISSN: 1435-2451
    Keywords: Computed tomography ; Crohn's disease ; Ulcerative colitis ; Differential diagnosis ; Computertomographie ; Morbus Crohn ; Colitis ulcerosa ; Differentialdiagnose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1981 wurden 109 Patienten mit Morbus Crohn und 31 Patienten mit Colitis ulcerosa prospektiv computertomographisch untersucht. Beim Nachweis colitis- und crohntypischer, extramucöser Befunde wie Fisteln, Abscesse, Darmwandverdickung und Mesenterialveränderungen war die CT der herkömmlichen radiologischen Diagnostik überlegen. Der hochfloriden Colitis ulcerosa und dem Colon-Crohn konnten computertomographisch typische Wandschichtungen zugeordnet werden, die in 4 von 6 unklaren Fällen mit reinem Colonbefall zur richtigen Diagnose führten. Der Stellenwert der CT in der präoperativen Abklärung und der Differentialdiagnose unklarer Colitiden wird unterstrichen.
    Notes: Summary Since 1981, 109 patients with Crohn's disease and 31 patients with ulcerative colitis have been investigated prospectively by computed tomography (CT). In the diagnosis of fistulas, abscesses, thickening of the bowel wall, and mesenteric pathology, CT was more sensitive than the usual radiological procedure. Pathognomonic layering of the bowel wall was demonstrated by CT in higly active ulcerative colitis and Crohn's disease of the colon. In 4 of 6 obscure cases of colitis, a clear distinction between Crohn's disease and ulcerative colitis was possible. The value of CT in preoperative assessment and differential diagnosis is to be emphasized.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 10 (1977), S. 151-156 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Acetylthioacetamides exist as different keto and enol isomers in chloroform solutions. The keto form with intramolecular hydrogen bonding between the NH and the carbonyl group is the dominant keto isomer. On the other hand the enol forms with intramolecular hydrogen bonding between the OH and the thioketo group are the dominant enol isomers in the temperature range 60°C to -60°C. The thermodynamic data of the keto-enol equilibria were obtained by measuring the intensities of appropriate high resolution proton signals as a function of temperature. At low temperatures all lines characteristic of the enol forms are doubled in the N-phenyl-substituted derivatives because the rotation of the NH—C6H5 group around the C—N bond becomes slow and the chemical shifts characteristic of the E and Z isomers are different. We estimated approximate thermodynamic data of the E/Z equilibrium in some of the compounds. The changes of the line shape as well as the chemical shifts as a function of temperature indicate the presence of various additional exchange processes. In order to obtain further information we performed curve fittings of the chemical shifts of one acetylthioacetanilide and of a series of monothio-β-diketones (studied in another paper) assuming a fast two site exchange process. On the basis of the results obtained a reaction scheme for N-substituted acylthioacetanilides in solution is proposed.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 18 (1983), S. 494-496 
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 19 (1982), S. 15-20 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: High resolution 1H NMR is applied to the study of hydrolysis and equilibria in the complex system of γ-[1-methyl-5-bis(β-chloroethyl)amino-2-benzimidazolyl]butyric acid and D2O. Kinetic data for the individual hydrolytic steps are obtained for the first time. The hydrolytic reactions are pseudo first order. The differences in the activation energies of the two hydrolysis steps are accounted for by different intermediates. Furthermore, equilibrium constants for the deuteration of the N mustard group in the individual products are quantitatively estimated. They show an increase of the basicity of N mustard with hydrolysis. The applicability of the 1H NMR method is restricted to a pD range of 0.5-4.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 18 (1983), S. 568-571 
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Unimolecular hydroxyl (OD·) loss from regio- and stereo-specifically labelled o-nitrostyrenes 1a, 1c and 1d results in the formation of an ion which upon collisional activation gives identical mass spectra. Suggestions are made which aim at explaining: (i) the loss of stereochemical integrity of the diastereotopic methylene hydrogens in the course of hydroxyl elimination; and (ii) to account for the collision induced losses of CO and HNC from the [M - hydroxyl]+ ion.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 31 (1993), S. 548-551 
    ISSN: 0749-1581
    Keywords: Mercury chlorides ; 199Hg chemical shifts ; Chemical exchange ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 119Hg NMR chemical shifts of the stable mercury species HgCln2 - n with n = 0-4 were determined by a least-squares algorithm from 199Hg chemical shifts measured in 50 mM aqueous mercury solution as a function of the chlorine concentration at 25°C. The concentrations of the corresponding mercury species in the solutions necessary in this special procedures were calculated by using published equilibrium constants. The results relative to dimethyl-mercury are -2256 ppm (Hg2+), -1897 ppm (HgCl+), -1560 ppm (HgCl2), -1436 ppm (HgCl3-) and -1152 ppm (HgCl42-) with maximum errors of ±5 ppm.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 7 (1978), S. 311-315 
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Previous vibrational assignments for Me4N+ are examined and in some respects revised. Frequency and intensity changes in the Raman spectra of Me4NCl solutions with variations of concentration and solvent (D2O and CD3OH) were observed mainly in the CH stretching and NC4 bending regions. These are interpreted in terms of cation-anion associations the extent of which is found to be much larger in methanolic than in aqueous solution. The effects of temperature on the Raman bands proved to be much smaller than those of concentration or solvent changes.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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